Circulating tumor DNA (ctDNA) is a type of cell-free DNA that originates from the shedding of tumor cells to the bloodstream and has recently been considered as a potential biomarker in colorectal cancer (CRC). This review covers the general features of ctDNA in terms of their bi...
Open access
Research Article10.9734/jcti/2025/v15i4329
Chukwum J. Okafor, Bart I. Ifionu, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan·Journal of Cancer and Tumor International·2025
Introduction: Prostatic diseases, including prostate cancer (CAP) and benign prostatic hyperplasia (BPH), are prevalent pathologies in ageing men. While prostate-specific antigen (PSA) is a well-established diagnostic marker, the role of serum testosterone in distinguishing betwe...
Open access
Research Article10.9734/jcti/2025/v15i4328
Prostate cancer remains the second most common malignancy among men worldwide and a leading cause of cancer-related mortality. MicroRNAs (miRNAs) and genomic signatures are critical regulators of oncogenic processes and represent promising biomarkers for cancer diagnosis and prog...
Open access
Research Article10.9734/jcti/2025/v15i4327
Ahoma Victor Mbanuzuru, Samuel I. Udobi, Christian Chibuzor Ibeh, Chinyere Mbanuzuru & Chukwuemeka Chukwubuikem Okoro·Journal of Cancer and Tumor International·2025
There is rapid growth and expansion of Telecommunication industry and infrastructures worldwide. In sub-Sahara Africa this has led to increased erection of base transceiver stations (BTS) often close to residential areas. The siting of telecommunication masts around residential b...
Open access
Research Article10.9734/jcti/2025/v15i4326
Background: Ovarian cancer is frequently diagnosed at advanced stages, requiring reliable and minimally invasive diagnostic tools. Fine Needle Aspiration Cytology (FNAC) has been proposed as a rapid and cost-effective method, but institutional data are essential to validate its r...
Open access
Research Article10.9734/jcti/2025/v15i4325
Obianujunwa Mercy Ubah, Michael Oshen Ogar, Safiyyah Temitope Ismaeel, Tobiloba Philip Olatokun, Rachel Adejoke Ojo & Lessly Kyei Poku·Journal of Cancer and Tumor International·2025
Non-smoker lung cancer represents a distinctive clinical and pathological entity, comprising 10-25 percent of all lung cancer cases globally. It possesses a unique epidemiology, histopathology, and molecular profile that fundamentally diverges from smoking-related diseases. This...
Open access
Research Article10.9734/jcti/2025/v15i4324
A 38-year-old Chinese gentleman presented to a private healthcare facility with a chief complaint of unilateral epistaxis, persisting for 2 months. An endoscopic examination revealed a polyp-like structure in the left nasal cavity, which bled upon contact. The patient underwent e...
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Research Article10.9734/jcti/2025/v15i4323
Onitsha, Enebrayi Nelson, Ezeiruaku, Ferdinand Chukwuma, Gborienemi George Simeon, Okutu, Jackson Borobuebi, Daniel Samuel, Lokoja Ebiweni James & Abiodun Funmilayo Tosin·Journal of Cancer and Tumor International·2025
Introduction: Shisha smoking has gained popularity globally and has become an emerging public health concern among adolescents and young adults. Unlike cigarette smoking, it is perceived as less harmful, yet emerging evidences indicate that it poses a serious risk to human health...
Open access
Research Article10.9734/jcti/2025/v15i4321
Gastric cancer remains a significant global health burden, with survival rates showing limited improvement despite advances in surgery and chemotherapy. It remains one of the most challenging malignancies for researchers and clinicians, with a poor prognosis and low five-year sur...
Open access
Research Article10.9734/jcti/2025/v15i4322
The pursuit of precision in oncologic surgery remains a critical challenge, as conventional resection techniques often face limitations in achieving tumour-free margins while minimising collateral tissue damage. In recent years, energy-based surgical modalities such as laser and...
Open access
Research Article10.9734/jcti/2025/v15i4320
Paxman Dandyson Uku, Emmanuel Wobo, Christine Abaiayam Dangana, Amarachi Faith Mbonu, Blessing Edna Amuah, Ayomide Wachuku, Doreen Obugheni Arugu & Chimankpam Edison Okechukwu Omeodu·Journal of Cancer and Tumor International·2025
Background: Treatment of haematologic malignancies with chemotherapy is associated with side effects. Chemotherapy-induced thrombocytopaenia, a recognized side effect, have been defined by nadir platelet counts, at different cycles of chemotherapy. A lot more studies describe thi...
Open access
Research Article10.9734/jcti/2025/v15i4319
Background: Cancer-related fatigue is one of the most prevalent and distressing symptoms experienced by cancer patients, often persisting beyond the completion of active treatment. Nutritional deficiencies during cancer treatment may contribute to fatigue and decreased physical f...
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Research Article10.9734/jcti/2025/v15i4318
Fortune Itoje Ebiala, Jumoke Ologun, John Kelenna Iregbu, Ogochi Blessing Chukwuneke, Aliaa Mohammed Mahmoud Soliman, Ayo Ebunolorun Ibukunoluwa, Rasheedat A. Busari MD, Oluwatobiloba Kehinde Adedokun & Lawrence John AJutor·Journal of Cancer and Tumor International·2025
Background: Oncogene addiction occurs in most tumour cells it is a phenomenon capable of driving colorectal cancer (CRC) growth, where tumour cells rely on genes like KRAS, BRAF, or MYC to survive. This has been so far seen as an exploitable target for precision therapies. Aim: T...
Open access
Research Article10.9734/jcti/2025/v15i3316
Fortune Itoje Ebiala, Cecilia Chika Unegbu, Precious Oluwamosope OKUNOLA, Ogochi Blessing Chukwuneke, Ololade Funke Olaitan, Ndubisi Ubaka Edebeatu & Damilola Ayodele Ojo·Journal of Cancer and Tumor International·2025
Beyond the human genetic codes, epigenetics also plays a key role in regulating how genes are expressed. While mutations or genes are known to be major causes of cancer, Epigenetic alterations, including DNA methylation, histone modifications, and non-coding RNAs, play critical r...
Open access
Research Article10.9734/jcti/2025/v15i3317
Medullary breast carcinoma (MBC) is a rare histological subtype of invasive breast cancer, accounting for less than 5% of all breast malignancies, and presents with a unique clinical paradox. Despite its aggressive histopathological features such as high-grade nuclei, prominent l...
Open access
Research Article10.9734/jcti/2025/v15i3314