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All published articles 373

Cytological Abnormalities in Sputum Samples of Sudanese Women Practicing Dukhan: A Descriptive Cross-Sectional Study in Shendi Town

Aamal Aabid Mohammed Ali, Mohammed Abdelgader Elsheikh, Abdalrhman Ali Alkhalifa Alhfyan, Ibrahim B Elemam, Asma Al-Ameer M. Zeen, Zeinab A Mohamed, Salwa Mohamed Abdelmajed Elmahjob & Ghanem Mohammed Mahjaf · Journal of Cancer and Tumor International · 2025

Background: Sputum cytology is a diagnostic technique used to examine sputum samples under a microscope to detect abnormal cellular changes. Dukhan, a traditional Sudanese smoke bath, is widely used by women, particularly in Shendi town, for therapeutic, cosmetic, and cultural pu...

Open access Research Article 10.9734/jcti/2025/v15i3315

Enhancing Cancer Treatment: Integrating Pharmacometrics and Personalized Medicine in Oncology

Krishnaveni Dharavath, Lavanya Pamarthi & P. Veeresh Babu · Journal of Cancer and Tumor International · 2025

This review article addresses the critical challenge of improving cancer treatment outcomes, with 19.3 million new diagnoses and 10 million deaths globally in 2020. It explores the integration of pharmacometrics and personalized medicine in oncology to enhance patient care. Pharm...

Open access Research Article 10.9734/jcti/2025/v15i3313

Role of CT Scan and MRI in Cancer Diagnosis: A Comparative Review of Imaging Modalities for Precision Medicine

Zeeshan Akram, Mohd Faraz, Urooj Fatima, Saqib Zameer, Zarrin Anwar, Shamsuddin, Safia Habib & Mohd Mustafa · Journal of Cancer and Tumor International · 2025

Cancer is one of the most lethal diseases in the current scenario all over the world. Early detection may lead to better treatment and recovery. Imaging modalities such as Magnetic resonance imaging (MRI) and Computed tomography (CT) are two modern diagnostic imaging techniques t...

Open access Research Article 10.9734/jcti/2025/v15i3312

Cancer Cachexia: The Interplay of Chronic Inflammation and Metabolic Wasting

Azeez M.O., Oyeleke B.T., Babatope S.A. & Adelakun A.A. · Journal of Cancer and Tumor International · 2025

Background: Cancer cachexia is a multifactorial syndrome characterized by involuntary weight loss, skeletal muscle wasting, and systemic inflammation. It significantly impairs patient quality of life, reduces tolerance to treatment, and contributes to poor prognosis. Objective: T...

Open access Research Article 10.9734/jcti/2025/v15i3310

Assessment of Vitamin A and D Status in Male Patients with Prostate Disorders in Lagos, Nigeria

Bart I. Ifionu, Chukwum J. Okafor, Ufuoma Ohwo, Nkem F. Obianagha, Emmanuel I. Obeagu, Omobolanle Abioye Ogundahunsi, E. N Adejumo & Seyi Samson Enitan · Journal of Cancer and Tumor International · 2025

Background: Vitamin A and D are both fat-soluble vitamins that are crucial for maintaining overall health and are highly indispensable, despite their minimal daily requirements. Their involvement in cell proliferation, differentiation, and apoptosis has linked them to the develop...

Open access Research Article 10.9734/jcti/2025/v15i3311

Value of Adjuvant Radiotherapy in Borderline and Malignant Phyllodes Tumors: Mansoura University Experience

Manal Mostafa S. Elghareeb, Nora Ahmed Shaband & Mohamed Saad Eldeen Elzahi · Journal of Cancer and Tumor International · 2025

Introduction: Phyllodes tumors are rare type of breast cancer. Surgery still the first option of treatment; post-operative treatment is a matter of debate specially when considering radiotherapy. Many risk factors could affect the incidence of local recurrence. Aim: Study the imp...

Open access Research Article 10.9734/jcti/2025/v15i3309

The Sudden Collapse of Cancer Cells: Exploring Tumor Lysis Syndrome through a Molecular and Therapeutic Lens

Ashik Anil Mathew, Ujwal H C, Diya Gibu, Aravind S Raj & Nijin Samuel Raju · Journal of Cancer and Tumor International · 2025

Tumor Lysis Syndrome (TLS) is an acute oncologic emergency triggered by the rapid destruction of malignant cells, resulting in a cascade of metabolic derangements including hyperuricemia, hyperkalemia, hyperphosphatemia, and hypocalcemia. This review synthesizes contemporary unde...

Open access Research Article 10.9734/jcti/2025/v15i3308

Why Cancer Immunotherapy Fails?: Mechanisms of Resistance and Emerging Reversal Strategies

Muhydeen Damilola Badru, Tobi Ayomide Lawal, Udeichi Nnenna Chidimma, Mayowa Josiah Badmus, Francis Esther Ene, Daniel Chinaza Anyirionye, Naomi Ngozichukwuka Ajoniloju, Adegbesan Abiodun Christopher & Comfort Mary Afolabi · Journal of Cancer and Tumor International · 2025

Cancer immunotherapy has revolutionized the field of oncology by enabling the immune system to target and destroy cancer cells. Therapies such as immune checkpoint inhibitors, including PD-1/PD-L1 and CTLA-4 blockade, and chimeric antigen receptor T (CAR-T) cells have shown unpre...

Open access Research Article 10.9734/jcti/2025/v15i3306

Artificial Intelligence and Machine Learning in Personalized Medicine: Emerging Technologies and Applications

Taiwo Oluwole FABIYI, Mary Oluwabunmi Oyebode, Kehinde Oluwafemi Fabiyi, Damilola Ayodeji Akinwale, Damilola Caroline Adeoye, Paul-Miki Raluchukwu Ibekwe, Olaitan Ololade Funke, Onyinye Henrietta Okolo & Irene Adjoa Anderson · Journal of Cancer and Tumor International · 2025

Personalized medicine is a revolutionary paradigm shift in the health sector, to customize medical decisions and initiatives to the distinct biological and contextual peculiarities of individual patients. This approach differs from the generalized strategies of traditional medici...

Open access Research Article 10.9734/jcti/2025/v15i3307

Decoding Tumor Heterogeneity through Multi Omics: Insights into Cancer Evolution, Microenvironment and Therapy Resistance

Paul-Miki Raluchukwu Ibekwe, Elizabeth Anuoluwa Akintayo, Cecilia Ndiuwem Okuku, Ismaila Muhammed, Fuhad Mayowa Jeje, Okun, Oseghale, Kemiki Olalekan Ademola, Muhydeen Damilola Badru & Lydia Amarachi Onwuemelem · Journal of Cancer and Tumor International · 2025

Background: The existence of genetically, epigenetically, and phenotypically distinct cell populations inside and between tumors is known as tumor heterogeneity, and it is one of the main barriers to effective cancer treatment. This intricacy affects the likelihood of metastasis,...

Open access Research Article 10.9734/jcti/2025/v15i3305

Minimally Invasive Management of Leukoplakia with Diode Laser: A Case Series

Himali Pun, Vibha Basavaraj Wodeyar, Peeyush Shivhare & Ajay Kumar · Journal of Cancer and Tumor International · 2025

Leukoplakia is a potentially malignant disorder affecting the oral cavity. Early detection and prompt treatment are the keys to prevent its malignant transformation. Various treatment modalities have been discussed in multiple literatures, broadly categorized into non-surgical an...

Open access Research Article 10.9734/jcti/2025/v15i3304

Rare Synchronous Colonic and Ovarian Carcinomas in a 26 Year Old Female Patient: A Case Report

Gbaa ZL, Ojo BA, Umobong E, Inienger DR, Unande HM, Kawen PT, Ugwu IV, Anenga RV, Ukaona SC & Gbaa FA · Journal of Cancer and Tumor International · 2025

Background: Synchronous primary malignancies, characterised by the diagnosis of two or more histologically distinct cancers within six months, are uncommon, and data from Sub-Saharan Africa is limited. Their occurrence in young individuals, particularly with colorectal and ovaria...

Open access Research Article 10.9734/jcti/2025/v15i3303

Astaxanthin's Role in Modulating Neuroinflammation and Oxidative Stress in Chemobrain

Udi Onoriode Andrew, OSAAT Roseline Sunday & Eduviere Anthony Taghogho · Journal of Cancer and Tumor International · 2025

Chemobrain, or chemotherapy-induced cognitive impairment (CICI), is a significant side effect affecting cancer survivors, characterized by neuroinflammation and oxidative stress. This review examines the potential role of astaxanthin, a potent antioxidant and anti-inflammatory ca...

Open access Research Article 10.9734/jcti/2025/v15i3302

Clinical Significance of CT and MR Perfusion Imaging in Cancer Diagnosis: Techniques, Parameters, and Diagnostic Implications

Zeeshan Akram, Mohd Faraz, Afshan Nigar, Rushda Parveen, Nimra Khan, Md Rashid Anwer, Adeeba Farooqui & Saqib Zameer · Journal of Cancer and Tumor International · 2025

Perfusion imaging is an advanced technique for evaluating the blood flow of the microvasculature of any tissue or pathology. It refers to the passing of blood from the arterial system to the vascular system through the microvasculature of tissues. It may be affected in abnormal t...

Open access Research Article 10.9734/jcti/2025/v15i3301

Binucleated Cells: A Comprehensive Review of Biological and Pathological Significance

Sajda Abdalraheem A. Abdalwahab, Asma Al-Ameer M. Zeen & Ghanem Mohammed Mahjaf · Journal of Cancer and Tumor International · 2025

Background: Binucleated cells are a type of cell that contains two nuclei within their cytoplasm and are commonly observed in both normal and pathological conditions. They play essential roles in physiological processes, such as tissue repair and adaptation, and are also implicat...

Open access Research Article 10.9734/jcti/2025/v15i3300