Hiba Ahmed Fadlallah Ahmed, Safa Habiballa Mohammed Ahmed, Saja Daffallah Abosara Mohamed, Salma Hashim Awadalkharim Alamain, Shaza Abulgasim Osman Alhaj bakheet, Zohal Kamal Dafallah Shams Aldeen, May Awad Mohammed Ashmeig, Muslih Haroun Elhussein Gamea & Ehab Mohammed Elmadenah Mohammed Ahmed·Journal of Cancer and Tumor International·2025
Introduction: Breast cancer is the most common malignancy among women worldwide, including in Sudan. Chemotherapy, a primary treatment modality, often results in hematological toxicity, impacting patients' overall health and treatment efficacy. This study aims to evaluate the cha...
Open access
Research Article10.9734/jcti/2025/v15i1284
Introduction: Keratoacanthoma Centrifugum Marginatum (KCM) is a rare variant of keratoacanthoma that closely mimics squamous cell carcinoma (SCC), posing significant diagnostic challenges. Case Report: A 45-year-old male presented with a progressively enlarging hyperkeratotic les...
Open access
Research Article10.9734/jcti/2025/v15i1283
Rauwolfia vomitoria fruits has been claimed to be used traditionally in treating cancer related diseases. However, this activity has not yet been scientifically proven. This study focused on investigating the cytotoxicity activity of this plant on Tadpoles (Raniceps raninus). The...
Open access
Research Article10.9734/jcti/2025/v15i1282
Md. Rubel Akanda, Sadia Jafrin, Shah Ashadul Islam, Shakir Hosen, Md. Mariful Islam, Nazmul Islam & Habibul Bari Shozib·Journal of Cancer and Tumor International·2025
There is mounting evidence linking certain lifestyle factors such as food, weight, and physical activity to an increased risk of breast cancer. Flavonoids are commonly used in traditional medicine. Plenty of studies have investigated the relationship between flavonoid consumption...
Open access
Research Article10.9734/jcti/2025/v15i1281
Lawrence John AJutor, Fatima Bello Sani, Elijah Nehemiah Kama, Kingsley Ugonna Ugoagwu, Adegbesan Abiodun Christopher, Daniel Temiloluwa Oyedemi, Peter Bemigho Adewoyin, Olayinka Esther Agbetanmije, Adepeju Matilda Adekoya & Erere Godsent Onyeugbo·Journal of Cancer and Tumor International·2025
Bioelectrical signals which are directed by ion channels and membrane potential (V_mem), play a crucial role in many cellular processes including proliferation and differentiation. It has also been known to influence processes such as gene expression, epigenetics, and tumor progr...
Open access
Research Article10.9734/jcti/2025/v15i1280
Glomerular filtration Rate (GFR) measured in steady state is the best marker of kidney function. Glomerular filtration rate can be determined using exogenous markers like inulin, iothalamate, or iohexol (mGFR), or estimated using endogenous markers like creatinine and cystatin C...
Open access
Research Article10.9734/jcti/2025/v15i1279
Inverted papillomas are benign tumours known for their locally aggressive behaviour, characterised by local tissue destruction, a high tendency to recur if resection is incomplete, and a risk of carcinomatous evolution into squamous cell carcinoma. Although most cases arise from...
Open access
Research Article10.9734/jcti/2025/v15i1278
Tumadir Mohamed Adam Ali, Mohamed Mahgoub Hassan Khalifa, Ahmed Abdalla Agab Eldour, Sirelkhatim Merghani Elkheir Mohammed & Hussain Gadelkarim Ahmed·Journal of Cancer and Tumor International·2024
Background: Tumor markers are crucial indicators for breast cancer treatment and follow-up. Thus, this study attempted to explore the expression patterns of ER, PR, Her2/neu, and Ki67 in Sudanese breast cancer patients. Methodology: This study was a retrospective descriptive anal...
Open access
Research Article10.9734/jcti/2024/v14i4277
The COVID-19 pandemic now had a broad impact on the health care system since its start. Cancer patients, specifically lung cancer patients, are undergoing a more vulnerable group due to their complex pathophysiological and immunological characteristics. Therefore, they need more...
Open access
Research Article10.9734/jcti/2024/v14i4276
Adamantinoma-like Ewing sarcoma (ALES), an extremely rare variant of Ewings sarcoma occurs primarily in the head and neck sites. ALES is characterized by basaloid cytomorphology, immunohistochemically expresses keratins, p63, p40, CD99, and harbors t (11; 22) EWSR1::FLI1 transloc...
Open access
Research Article10.9734/jcti/2024/v14i4275
Walter Lim Yung Chwen, Asmah Hanim Bt Hamdan, Nurul Aifa Binti Zahari, Intan Bazilah Binti Abu Bakar & Azwan Halim Abdul Wahab·Journal of Cancer and Tumor International·2024
Osteosarcoma is one of the most common types of malignant bone tumors, typically involving long bones such as the femur, tibia, and humerus. However, osteosarcomas occurring in the jaws are exceptionally rare, accounting for approximately 7% of all osteosarcoma cases and just 1%...
Open access
Research Article10.9734/jcti/2024/v14i4274
Introduction: Gastric carcinoma is the fifth most frequently diagnosed tumor and the fourth leading cause of death. They represent a heterogenous group of tumors with multifactorial etiologies, both environmental and genetic. PD-L1 is a transmembrane protein, and a positive PD-L1...
Open access
Research Article10.9734/jcti/2024/v14i4273
Nephroblastoma (Wilm’s Tumour) is the commonest paediatric renal cancer worldwide. It is uncommon in infants less than six months of age and very rarely seen in neonates. The uncommon presentation of nephroblastoma in the newborn period of this two month old, depicts the possibi...
Open access
Research Article10.9734/jcti/2024/v14i4272
Aims: This study aims to provide a comprehensive review of the epidemiology, genetic underpinnings, clinical presentation, and management strategies of congenital mesoblastic nephroma (CMN), with a focus on the diagnostic and therapeutic challenges that distinguish it from other...
Open access
Research Article10.9734/jcti/2024/v14i4271
Dewa Ayu Made Adnyaswari, Agung Wiwiek Indrayani, IGusti Ayu Artini, Desak Ketut Ernawati, I. Gusti Made Gede Surya Candra Trapika, Ni Putu Sriwidyani & I Gusti Kamasan Nyoman Arijana·Journal of Cancer and Tumor International·2024
Aims: Hepatocellular carcinoma accounts for approximately 90% of all primary liver malignancies and poses a major global health challenge. The initiation of hepatocellular carcinoma (HCC) is marked by a progressive accumulation of molecular alterations, the origins of which remai...
Open access
Research Article10.9734/jcti/2024/v14i4269