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All published articles 419

Comparative Assessment of Phostoxin-Induced Biochemical and Histopathological Renal Toxicity in Male and Female Wistar Rats

Etu Esther Ifeyinwa, Peter Uwadiegwu Achukwu, Nyejirime Young Wike, Azubuike Nkiruka & Onyemelukwe Anulika · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Phostoxin, an aluminium phosphide–based pesticide, is widely used as a fumigant but poses significant health risks due to its potential to cause oxidative and organ toxicity. Aim: This study conducted a comparative assessment of phostoxin-induced biochemical and histo...

Open access Research Article 10.9734/ajrimps/2026/v15i4423

Comparative Effects of Atracurium and Rocuronium on Perioperative Blood Glucose in Non-Diabetic Patients Undergoing Appendectomy under General Anesthesia

Hayder Hasan Khudhiar & Alaa Alsafi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Aims: To compare perioperative capillary blood glucose levels between non-diabetic patients receiving atracurium or rocuronium during general anaesthesia for appendectomy. Study Design: A prospective, randomised, two-group clinical study. Place and Duration of Study: The study wa...

Open access Research Article 10.9734/ajrimps/2026/v15i4424

Neuropathological Changes Induced by Microplastics Associated with Sachet Water in Wistar Rats: Implications for Human Neurological Health

Victor C. Chibueze & Raphael C. Anakwue · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: The widespread consumption of sachet water in Nigeria has raised concerns about microplastic contamination and associated health risks, particularly after environmental exposure during storage. Although microplastics have been associated with oxidative stress and neur...

Open access Research Article 10.9734/ajrimps/2026/v15i4422

Prospective Evaluation of a Structured Management Protocol for Adhesive Small Bowel Obstruction: Gastrografin and Initial Severity Stratification

Mehdi Karami, Amine Maazouz, Srir Leila, Hind Hablaj, Ihab Lechhab, Walid Chair, Mohamed Bouzroud, Hakim EL Kaoui, Mountassir Moujahid, Ahmed Bounaim & Sidi Mohammed Bouchentouf · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Adhesive small bowel obstruction (ASBO) is a frequent surgical emergency, and identifying patients who require early operative intervention remains challenging. Aim: This study evaluated outcomes under a structured management protocol incorporating initial severity st...

Open access Research Article 10.9734/ajrimps/2026/v15i4421

Distribution of Sorbic Acid Tube Precipitation and Leukocyte Adherence Inhibition Results in Two Clinically Selected Patient Cohorts: A Retrospective Descriptive Study

Celso Eduardo Olivier, Daiana Guedes Pinto, Ana Paula Monezzi Teixeira, Cibele Silva Miguel, Nicole Sartoreto Rocha, Alessandra Vieira de Oliveira, Luciana Sacilotto Carvalho & Raquel Acácia Pereira Gonçalves Santos · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Hypersensitivity has been reported in association with sorbic acid and sorbate salts in susceptible individuals. Objective: This retrospective descriptive analysis characterised the distribution of Tube Titration of Precipitins (TTP) and Leukocyte Adherence Inhibition...

Open access Research Article 10.9734/ajrimps/2026/v15i4420

Utilization, Correlates and Predictors of Contraceptive Use among Married Women in Amassoma, Bayelsa State, Nigeria

Timi Fiekumo Buseri, Success Tamunoibi Gwembe, Ibegi, Ibegi Saviour, Keme Kelvin Yenagoa, Goodluck Cross & Buseri, Oyintokoni Beauty · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Nigeria's national modern contraceptive prevalence rate among married women remains low, at roughly 12% to 20%, with wide sub-national variation, and a recurring explanation is that awareness of contraceptives does not reliably translate into use. This study determine...

Open access Research Article 10.9734/ajrimps/2026/v15i4419

Haloperidol as a Novel Augmentation Strategy in Treatment-Resistant Depression: A Clinical Practice Perspective with Case Series

Giovanna Azevedo Rodrigues, Fernando Martins Castanheira Júnior, Luiz Costa & Marcelo Caixeta · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Treatment-resistant depression (TRD) remains a major clinical challenge when adequate antidepressant trials fail to achieve remission. This clinical practice perspective examines low-dose haloperidol as a potential augmentation strategy in carefully selected, treatment-refractory...

Open access Research Article 10.9734/ajrimps/2026/v15i4418

Hyperbaric Oxygen Therapy in Non-Healing Wounds: A Critical Narrative Review of Mechanisms, Clinical Applications and Outcomes

Ketan Vagholkar · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Non-healing wounds impose a substantial and rising clinical and economic burden, and hyperbaric oxygen therapy remains one of the most contested adjuncts in their management. Half a century of mechanistic work has established that intermittent hyperoxia raises dissolved plasma ox...

Open access Research Article 10.9734/ajrimps/2026/v15i4417

Safe Medicine Storage and Disposal among Pharmacy and Engineering Students: A Kap Study with Pre-Post Knowledge Assessment

R. Nayana, Lalruatfeli, Lalnunsiami, V. S. Sowmya & A. M. Shobha · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Improper storage and disposal of unused, unwanted, and expired medicines can compromise medication safety and contribute to environmental contamination. University students are an important group for promoting responsible medicine-handling practices. Objective: To ass...

Open access Research Article 10.9734/ajrimps/2026/v15i3415

Knowledge and Utilization of the WHO Surgical Safety Checklist among Perioperative Nurses in Two Nigerian Teaching Hospitals: A Comparative Cross-Sectional Study

Bolatito Temitope ONIFADE, Olusola O. Akanbi, Rafiat Omotayo Ishola, Johnson Adewale Akinoso, Adetunmise Oluseyi OLAJIDE & Ganiyat Odunola ADENIRAN · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background and Objective: The World Health Organization Surgical Safety Checklist (WHO SSC) reduces preventable perioperative harm when implemented with fidelity, yet knowledge may not translate into consistent use. This study compared knowledge and utilisation of the WHO SSC amo...

Open access Research Article 10.9734/ajrimps/2026/v15i3414

Late-Onset Multiple Acyl-CoA Dehydrogenase Deficiency (MADD / Glutaric Acidemia Type IIC) Presenting as Chronic Sensory Ataxic Ganglionopathy, Bilateral Sensorineural Hearing Loss, and Vocal Cord Dysfunction Associated with a Novel ETFDH Variant

B. B. Likhitha, Akshata N. Chavadi & Shashank N. Pastay · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Multiple acyl-CoA dehydrogenase deficiency (MADD), also known as glutaric acidaemia type II (GA II), is a rare inherited autosomal recessive disorder involving the metabolic pathways of fatty acid and amino acid oxidation. Catastrophic metabolic crises are observed in...

Open access Research Article 10.9734/ajrimps/2026/v15i3412

Scoliosis in Adults Aged 50 Years and Older: Prevalence, Patterns, Associated Factors, and Evidence Gaps with Special Emphasis on Enugu Metropolis, Nigeria

Chukwu, Chidera Victoria · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Scoliosis identified in later adulthood is increasingly recognised as an age-related spinal health problem, but its epidemiology remains difficult to quantify because adult scoliosis combines different aetiologies and because prevalence estimates are highly sensitive to sampling...

Open access Research Article 10.9734/ajrimps/2026/v15i3413

Neuroprotective Effects of Eleveted Dose Vitamin A on the Hippocampus of Adult Male Wistar Rats Exposed to Toxic Doses of Methamphetamine

Ezejindu Damian NNABUIHE, Joshua Izuchukwu ABUGU, Enemuo IJEOMA, Okeke Somadina Nnamdi, K. Ogbuokiri Doris, Okeke Henry Kachikwuru, Ekoh Augustine Alobu, Benedict Nzube Obinwa, Chinyere Elizabeth Eze, Nwaefulu Kester Eluemunor, Sobanke A. Omolara, Chidinma Ifeyinwa Mmaju, Okafor Anulika Jacinta, Chuka-Onwuokwu Ngozi Cynthia, Ejiogu Ikedichukwu Chibueze, Nwoko Sebastine Okechukwu, Wuraola Serah Nnaemeka, Ebi Victory Chinecherem, Agu Augustine Uchenna, Ugwu Augustus Uchenna, Nwodo Ndubuisi Francis, Elemuo Chukwuebuka Stanley, Agbai Johnson Ukwa, Muorah Chinecherem Onyekachi & Ozoemena Chiadikobi Lawrence · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Methamphetamine overstimulates brain regions such as the striatum and hippocampus by increasing neurotransmitter activity, thereby causing neurotoxicity, whereas vitamin A may help protect neurons through anti-inflammatory and neuroprotective effects. This study investigated the...

Open access Research Article 10.9734/ajrimps/2026/v15i3410

Bioactive Evaluation and Antimicrobial Activities of Nigerian Mistletoe (Phragmanthera incana) Leaf Extracts

L. E. Gambo, D. A. Dashak & A. M. Lohdip · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Mistletoe is a hemiparasitic medicinal plant traditionally used for several human and animal ailments. This study evaluated the phytochemical constituents and antibacterial activity of aqueous and methanolic leaf extracts of Nigerian mistletoe parasitic on Stereospermum kunthianu...

Open access Research Article 10.9734/ajrimps/2026/v15i3411

Proximate Analysis and Antioxidant Activity Studies on Santalaceae (Viscum album) Leaf Extract

L. E. Gambo, D. A. Dashak & A. M. Lohdip · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

This study characterised the methanolic leaf extract of mistletoe (Viscum album) parasitic on Moringa oleifera by assessing its phytochemical constituents, trace elements, extract yield, and in vitro DPPH radical-scavenging activity. Leaves collected in Nasarawa State, Nigeria, w...

Open access Research Article 10.9734/ajrimps/2026/v15i3409