Paracetamol is one of the most widely used analgesics and antipyretics but can cause severe liver damage at high doses. This study explores the potential protective effects of ascorbic acid (vitamin C) against paracetamol-induced hepatotoxicity in Wistar rats. For this experiment...
Open access
Research Article10.9734/ajrimps/2024/v13i4269
Aim: To achieve systemic availability of an oral dosage form of gentamicin sulfate (GS), typically impermeable via the gastrointestinal tract. Study Design: Formulation and physical characterization of GS nanoemulsion. Stability studies and ex vivo bioavailability evaluation of t...
Open access
Research Article10.9734/ajrimps/2024/v13i3268
Introduction: The proliferation of fake drugs and the multiple resistance seen in conventional fungicidal drugs has led to the use of medicinal plants to treat fungal infections. There are claims that Jatropha tanjorensis and Adansonia digitata have fungicidal potentials, hence t...
Open access
Research Article10.9734/ajrimps/2024/v13i3267
In the domain of vaccination, DNA antibodies have transformed into a striking methodology that appreciates different high grounds over ordinary vaccination modalities. A design of the vital considerations behind DNA vaccinations, their technique for action, and energy upgrades in...
Open access
Research Article10.9734/ajrimps/2024/v13i3265
Introduction: Liver injury can result from various causes, including alcohol consumption, viral infections (such as hepatitis), autoimmune diseases, metabolic disorders, and exposure to certain chemicals, drugs or toxins. It can manifest as inflammation, fatty liver disease, cirr...
Open access
Research Article10.9734/ajrimps/2024/v13i3266
Aims: To do a comparative study of the anti-elastase activity of the extract, extract-loaded gelatin nanoparticles, and serum gels of Indonesian Bilberry leaves. Methods: Extraction of the leaves used the maceration method with 70% ethanol at a pH of 2 and dried using a rotavapo...
Open access
Research Article10.9734/ajrimps/2024/v13i3264
America's healthcare system faces a critical juncture marked by escalating costs, disparities in access, and systemic inefficiencies. This paper explores the imminent crisis, analyzing factors contributing to its complexity and urgency. Through examination of current trends and p...
Open access
Research Article10.9734/ajrimps/2024/v13i3263
Evaristus Chinonso Odoh, Shadrach Chinecherem Eze, Ugomma Loveth Anyaji, Kingsley Chinemerem Eze, Emmanuel Chijiekwu Nwachukwu, Gerald Obinna Ozota, Kenneth Chukwuebuka Egwu, Caleb Chijindu Ugorji, Joy Chekwube Onyesoro, Chimaobi Jude Nwiyi, Njoku Chukwuemeka Chidindu, Victor Chukwuebuka Akwu, Wisdom Enyinnaya Arugo & Chioma Chikezie Igu·Asian Journal of Research in Medical and Pharmaceutical Sciences·2024
Background: The prevalence of self-medication is increasing, not only among the general public but also among college and university students in the health field. Aim: This study aims to assess the knowledge, perception and practice of self-medication among pharmacy students in t...
Open access
Research Article10.9734/ajrimps/2024/v13i3262
Breast cancer is one of the most prevalent and fatal forms of cancer in India. It ranks the second most common cancer in rural areas and the most common in urban areas. According to a report by the International Agency for Research on Cancer, there were over 2.26 million new brea...
Open access
Research Article10.9734/ajrimps/2024/v13i3261
Atiba Kehinde Peter, Onyemeh Linda Oluchi, Sunday Kolawole Akomolede, Paul Obaloluwa Ojetayo, Patricia Okwuchi Nneji, Aniekwensi Obinna Patrick, Gemadi Kwasi Shine, Adedoyin Tinuade Buari, Olajide Sarah Olulana & Manawa Oghenevware·Asian Journal of Research in Medical and Pharmaceutical Sciences·2024
Introduction: Datura stramonium (DS) is a medicinal plant widely distributed across the globe, including in Nigeria and West Africa. Pharmacological, physiological, and histological studies have demonstrated the neurotoxicity of the plant in animals and humans. Ascorbic acid is a...
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Research Article10.9734/ajrimps/2024/v13i3260
Active components in medicinal plants possess therapeutic indications in disease states. Aim: The present investigation evaluated the activity of fraction from Dryopteris dilatata leaves modulating diabetogenic and oxidative stress activity in alloxan-induced diabetic Rats. Metho...
Open access
Research Article10.9734/ajrimps/2024/v13i3259
The study examines the relationship between self-medication and patronage of orthodox medical facilities in Yakurr Local Government Area, Cross River State, Nigeria. Three research objectives were drawn which guided the formulation of three null hypotheses from the independent va...
Open access
Research Article10.9734/ajrimps/2024/v13i3258
This study aimed to investigate the effect of increased iron concentration in water and the potential protective efficacy of ginger (Zingiber officinale Roscoe) against hematological disturbances. A cohort of 24 Wistar rats, aged 6-8 weeks before dosage with an average weight of...
Open access
Research Article10.9734/ajrimps/2024/v13i2257
Aims: Diabetes mellitus, a condition characterized by glucose receptor abnormalities affecting glucose uptake, affects approximately 600 million individuals globally as of 2021. This study aimed to assess the antilipidemic and renal effects of aqueous extracts from the root bark...
Open access
Research Article10.9734/ajrimps/2024/v13i2256
Eugene Ohams Ohanme, Ogbonnaya Nnabuike Iganga, Casimir Chijioke Ofor, Uzochukwu Ofonakara, Amucheukwu Veronica Nwafor, Clementina, Nkiru Eze, Kenneth Eze Etu, Benjamin Nwafocha Nwakelu & Chiazor Prince Unekwe·Asian Journal of Research in Medical and Pharmaceutical Sciences·2024
The primary goal of drug metabolism, sometimes referred to as pharmacokinetic process, is to change a medication's chemical structure to make it more readily excretable. Typically, phase I and phase II reactions involve this mechanism. Xenobiotics can stimulate or inhibit the act...
Open access
Research Article10.9734/ajrimps/2024/v13i2255