Skip to content

All published articles 419

Evaluation of the Efficacy of Herbal Antidotes of Viper Snakes through In-silico Docking Analysis of their Bioactive Components Targeting Phospholipase A2

R. Sathish Adithya & S. Kanimozhi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2023

Introduction: Snake bite is common in Rural areas. Many toxic snakes produce neurotoxic, Myotoxic, and hemotoxic effects. Snake venom is rich in metalloproteinases and Phospholipases. PhospholipaseA2 accounts for most of the toxic effects of Viper snakes. Many herbal antidotes ha...

Open access Research Article 10.9734/ajrimps/2023/v12i1209

Phytochemical and Anti-ulcer Properties of Allophylus africanus P Beauv. (Sapindaceae) Leaf

Chikeokwu Ikenna, Mba Theodora C., Uche Estella Odoh & Christopher Ugwuoke · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2023

Introduction: Ulcer has remained a persistent discomforting illness commonly causes by the bacteria Helicobacter pylori and prolonged or excessive use of anti-inflammatory pain killers like aspirin. While existing cases are difficult to treat and ,treat new cases are being diagno...

Open access Research Article 10.9734/ajrimps/2023/v12i1208

Health Economic Evaluations for Alzheimer’s Disease: Pathophysiology, Diagnosis and Pharmacological Approaches

Rahul Raj, Prolay Paul, Yogesh Motwani, Aashutosh Sinwal & Ishu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2023

Alzheimer's disease (AD) was first described by Alois Alzheimer in 1907 as a slowly progressing form of dementia that affects cognition, behavior, and functional status. It may be identified by the extracellular amyloid b (Ab) plaques as well as neurofibrillary tangle (NFT) depos...

Open access Research Article 10.9734/ajrimps/2023/v12i1207

A Review on Benzothiazole Derivatives and Their Biological Significances

Rima Mahapatra & Kuntal Hazra · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2023

Benzothiazole is a molecule that has a wide range of pharmacological activities. The addition of a fluorine atom into the structure of benzothiazole enhances the various activities of the drug as the alteration of hydrogen or oxygen atom from a carbon bond by a fluorine atom impr...

Open access Research Article 10.9734/ajrimps/2023/v12i1206

The Best Time to Dental Implant Placement in Patients with Head and Neck Cancers: An Ever-going Debate

Efsun Somay, Busra Yilmaz & Erkan Topkan · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2023

With 500,000 new cases diagnosed each year, head and neck cancers (HNC) are among the most prevalent cancers in the world. The most effective organ-sparing therapy for patients with locally advanced HNC is concurrent chemoradiotherapy (C-CRT). Many HNC patients lose multiple teet...

Open access Research Article 10.9734/ajrimps/2023/v12i1205

Mature Wistar Rats' Spleen and Liver Histomorphological Changes Related to the Duration of Atrazine Exposure

Praise Ajiri Odi, Onoriode Andrew Udi, Lilia Ebeye Chris-Ozoko & Mega Obukohwo Oyovwi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background: Spleen and liver is secondary lymphoid organ that is highly sensitive to different chemicals. Widespread use of pesticides in agriculture has always been a matter of concern.  And surprisingly, atrazine distinguishes out for being used more frequently among numerous h...

Open access Research Article 10.9734/ajrimps/2022/v11i4204

Pumpkin (Cucurbita pepo) Fruit Extract Attenuates Paraquat-induced Toxicity in Wister Rats

Bawa Y. Muhammad, Sulaiman A. Barau, Moses Z. Zaruwa, Rabiu M. Modibbo & Saidu B. Ibrahim · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Introduction: Paraquat is a bipyridil herbicide commonly used in modern agriculture for weed and pest control. Paraquat poisoning usually occurs through direct ingestion for suicidal intent, causing mortality as a consequence to oxidative damage, inflammation and multi-organ fail...

Open access Research Article 10.9734/ajrimps/2022/v11i4203

Ascaris lumbricoides Infestation of Bile Ducts: Case Report

Mohammad Saeed Sarwar, Ashraf ALakkad & Hossam Aldin Fawzy · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background: Ascariasis is a common helminthic disease that affects the gastrointestinal tract of human beings and is caused by the Ascaris lumbricoid worm. Most of the time, this parasite resides in the intestinal lumen, but it can occasionally travel to the biliary tract through...

Open access Research Article 10.9734/ajrimps/2022/v11i4202

Identification and Antibiotic Resistance Profile of Biofilm-forming Methicillin Resistant Staphylococcus aureus (MRSA) Causing Infection among Orthopedic Wound Patients

Ikemesit Udeme Peter, Ijeoma Onyinye Okolo, Henrietta Onyinye Uzoeto, Christiana Inuaesiet Edemekong, Mandu Daniel Thompson, Ezinwanne Blessing Chukwu, Ismaila Danjuma Mohammed, Idongesit Joseph Ubom, Ofonmbuk Victor Joseph, Agabus Chidiebube Nwuzo, Peace Oluchi Akpu & Ifeanyichukwu Romanus Iroha · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background and Objectives: The biofilm-forming ability of Methicillin-Resistant Staphylococcus aureus(MRSA) strains have demonstrated the involvement of MRSA biofilm in antibiotic resistance, recalcitrant and persistent infections in humans. Despite a deeper understanding of the...

Open access Research Article 10.9734/ajrimps/2022/v11i4201

Effect of Ethanolic Leaf Extract of Vernonia amygdalina on Haematological Parameters in Albino Rats

Immaculata O. Uduchi, Jacinta C. Elo-Ilo, Emmanuel C. Ogbodo, Stella N. Kanu & Eric E. Okereke · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

It has been demonstrated that Vernonia amygdalina, often known as the bitter leaf, offers a range of medical benefits that can improve human health. This study was designed to investigatethe effects of V. amygdalina (VA) ethanolic leaf extracts on some haematological parameters i...

Open access Research Article 10.9734/ajrimps/2022/v11i4200

Hepatocellular Injury Ameliorated by a Common African Food, Parkia biglobosa

O. I. N. Onyekachi, S. F. Orji, C. N. Ugwu, C. Igwenyi, C. L. Uche, I. O. Abali, M. U. Nwobodo, C. E. Iwuoha, N. M. Chika-Igwenyi, C. A. Onyeaghala, F. U. Agu & A. I. Airaodion · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Background: Parkia biglobosa seed has been reported to possess hepatoperotective potential. Therefore, this study sought to investigate its ability in ameliorating KBrO3-induced hepatotoxicity. Methodology: P. biglobosa was extracted with soxhlet extractor with 95% ethanol as the...

Open access Research Article 10.9734/ajrimps/2022/v11i4199

Pregnancy and COVID-19: A Systematic Review

Dipu Das, Namita Rani Sinha, Shahina Akhter, Tahmina Sharmin & Sandip Kanungo · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

In Bangladesh, the 2019 coronavirus disease (COVID-19) pandemic has already resulted in 1.52 million cases of sickness and 26,794 deaths by 2021-09-09. As a result of hormonal and physiological shifts, pregnant women may be more vulnerable to life-threatening lung infections. Dur...

Open access Research Article 10.9734/ajrimps/2022/v11i430195

Effect of Different Drying Methods and Storage Time on Quality of Roselle Calyxes (Hibiscus sabdariffa L.) Plants

Hanem, A. Abd Elghany, Zeinab A. El Swaify & Zeinab A. Abd Elhafez · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

This research was conducted during the 2018 and 2019 seasons, and the aim of the research was to study the effect of each of the different drying methods (drying in the shade, direct sunlight, electric ovens, and solar dryer) and the different storage periods (0, 2, 4 and 6 month...

Open access Research Article 10.9734/ajrimps/2022/v11i430194

Antihyperlipidemic Studies of Methanolic Extract of Gossypium herbaceum: An In silico and In vivo Approach

N. V. L. Suvarchala Reddy V, M. Ganga Raju, M. Mamatha & Shabnam Kumari Thakur · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

Aim: To evaluate anti-hyperlipidemic activity of the whole plant of Gossypium herbaceum extract in Wistar Albino Rats. Methods: The whole plant of Gossypium herbaceum were collected and extracted with methanol by soxhlation. It was tested in Triton and Propylthiouracil (PTU) indu...

Open access Research Article 10.9734/ajrimps/2022/v11i330193

Different Areas of Carica papaya Linn Display Antifungal and Antimicrobial Activity

Ram Vighne, Gaurav Mude, Chaitali Dangore, Mona Kapse & Sudarshan Behere · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2022

The plants of Carica papaya are utilised for nutritional and therapeutic purposes. The phytochemical examination of the leaf extract of Carica papaya reveals all phytochemical elements, including saponin, flavonoid, glycoside, alkaloid, carbohydrates, tannins, and steroids. A sys...

Open access Research Article 10.9734/ajrimps/2022/v11i330192