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All published articles 419

Development & Validation of RP-HPLC Method for the Estimation of Doravirine in Bulk and Pharmaceutical Dosage Form

A. Suneetha, G. I. Priyadarshini, V. Mounika & G. Aparna · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

A simple, accurate, rapid and precise isocratic reversed phase high-performance liquid chromatographic method has been developed and validated for determination of Doravirine in tablets. The chromatographic separation was carried out on Dionex C18 (250 x 4.6mm, 5µ) with a mixture...

Open access Research Article 10.9734/ajrimps/2021/v10i430174

Effects of Medical Drugs According to Sweating Localization in Primary Hyperhidrosis

Bayrakçi Onur · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Background: Primary hyperhidrosis is excessive sweating localized to different parts of the body, mostly on the hands. It is exact cause  unknown, negatively affects the psychosocial structure of the person and a clinically important health problem. Aims: In the study, it was aim...

Open access Research Article 10.9734/ajrimps/2021/v10i430173

Placebo effect unboxed: A Review

Sharique Ahmad, Tanish Baqar, Shivani Singh, Saeeda Wasim, Shivangi Shukla & Huma Parveen · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

As in our body, brain is the most powerful part and our mind could be excellent healing tool when any chance is provided. The idea that our brain can be one of the convincing parts in our body for the fake treatment is the real point this is called as placebo effect [1]. This eff...

Open access Research Article 10.9734/ajrimps/2021/v10i430172

Antioxidant Potentials of Aqueous Leaf Extract of Acalypha godseffiana on Hydrogen Peroxide-Induced Oxidative Stress in Wistar Rats

Samson Eruke Okoro, Stephen I. OMEODU & Favour Uzoma Iyke-David · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Aim: This study evaluated the efficacy of aqueous extract of Acalypha godseffiana leaves against H2O2-induced oxidative stress and organ damage in wistar rats by measuring hepatotoxic biomarkers, nephrotoxicity and status of the antioxidant defense system. Study Design: Twenty-fi...

Open access Research Article 10.9734/ajrimps/2021/v10i430170

Hepatic Enzyme Effects of an Imperata cylindrica Extract

M. O. Nwokike, S. I. Ghasi, E. C. Ogbuagu, M. N. Ezenwaeze & Akpotu E. Ajirioghene · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

This study was performed to investigate the effects of aqueous Imperata cylindrica root extract on hepatic enzyme levels of alloxan-induced diabetic male Wistar rats. Forty (48) male wistar rats were divided into six groups consisting of eight animals each. Diabetes mellitus was...

Open access Research Article 10.9734/ajrimps/2021/v10i330168

The Theoretical Investigations and Molecular Dynamic Stimulation of Isoniazid as a Corrosion Inhibitor

O. E. Obolo, D. T. Oloruntoba & J. O. Borode · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

API5L Steel is known as one of the most useful materials on earth which is also subject to corrosion in certain environments. Many methods have been used to minimize its corrosion, but the use of inhibitors is widely accepted. The use of green inhibitors has gained wide usage bec...

Open access Research Article 10.9734/ajrimps/2021/v10i330167

Zero Prevalence of HIV and HCV Coinfection in the Highly HIV-infected Population of Rivers State, Nigeria

Iheanyi O. Okonko, Tochi I. Cookey & Nnenna Frank-Peterside · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Background: Hepatitis C affects 5–15% of the 38 million people living with HIV globally. Africa which has the second highest prevalence of HIV/HCV co-infection following Asia. This alarming statistics has made it crucial that studies be done to also ascertain the HIV/HCV co-infec...

Open access Research Article 10.9734/ajrimps/2021/v10i330164

Evaluation of In vitro Antioxidant and Qualitative Phytochemical Analysis of Methanol Leaf Extract of Fadogia cienkowskii Scheinf Fam. Rubiaceae

Vincent O. Chukwube, Elejeje O. Okonta, Christopher O. Ezugwu & Uchenna E. Odoh · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Aim: Fadogia cienkowskii Scheinf has been used in ethno medicine for the treatment of pyrexia, convulsion in children, inflammation and malaria. The aim of this work is to ascertain the presence of some phytochemicals in the leaf of Fadogia cienkowskii Scheinf and to investigate...

Open access Research Article 10.9734/ajrimps/2021/v10i330165

Assessment of Health Risk of Daily Fluoride Intake of Some Selected Dentifrices used in Port Harcourt, Nigeria

Kpalap, Pretty Tonubari, Bartimaeus, Ebirien-Agana Samuel & Brown, Holy · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Background: Several dentifrices are marketed and used by individuals for the purposes of cleaning and maintaining the aesthetic and health of the teeth, promote oral hygiene and aid in removal of dental plaque and food materials from the teeth. This study was thus designed to ass...

Open access Research Article 10.9734/ajrimps/2021/v10i330163

Predictors of Severe Perineal Tear during Delivery in Yenagoa, Southern Nigeria

Ikobho Ebenezer Howells & Isaac Joel Abasi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Background:Perineal tear is a very common complication of vaginal delivery, and it is often mild. However, when severe, it could result in torrential life threatening hemorrhage and anal sphincter injury, with fecal incontinence. Objective: The objective of this study is to deter...

Open access Research Article 10.9734/ajrimps/2021/v10i230162

Orodispersible Films as a Solution to Drug Acceptability Issues: A Short Review

Mohamed Yafout, Hicham Elhorr, Amine Ousaid, Ibrahim Sbai El Otmani & Youssef Khayati · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Despite the fact that the tablets are the most widely used dosage form, they are not suitable for young children and patients with swallowing difficulties, especially the elderly. Orodispersible films (ODFs) dissolve rapidly in the mouth and deliver an accurate amount of the acti...

Open access Research Article 10.9734/ajrimps/2021/v10i230161

Telemedicine in Covid-19: Challenges and Opportunities

Imrana Masood, Ummul Baneen & . Nivedita · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

The pandemic of COVID -19 is a healthcare emergency of International concern. It originated in Wuhan, China in December 2019 and was declared as pandemic by WHO on 12 March 2020. Since then it is raging relentlessly across the world with staggering more than 60 lakh cases in Indi...

Open access Research Article 10.9734/ajrimps/2021/v10i230160

Evaluation of the Binding Properties of a Polymer Obtained from Modification of Triticum aestivum Starch in Metronidazole Tablets Formulation

Nkemakolam Nwachukwu, Kenneth Chinedu Ugoeze & Azuka Ijoma Alumona · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Aim: The binding properties of a polymer obtained from modification of Triticum aestivum (TA) starch in metronidazole tablets formulation were evaluated. Study Design: Experimental design. Place and Duration of Study: Department of Pharmaceutics and Pharmaceutical Technology, Uni...

Open access Research Article 10.9734/ajrimps/2021/v10i230159

Factors Associated with Prognosis of Non-Alcoholic Fatty Liver Disease

Muamar M. A. Shaheen, Mohanad Saleh, Deema Sider, Reem Al Natsheh & Raghad Dweik · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

Background: At the junction between obesity, metabolic syndrome and liver failure, lies Non-alcoholic fatty liver disease. Recent studies elaborated on role of metformin in patients with non-alcoholic fatty liver disease. This observation has not been studied at a global scale, n...

Open access Research Article 10.9734/ajrimps/2021/v10i230158

Changes in Antioxidants in the Brain of Fluoride-Treated Rats

Abdulrahman Abdullateef, Rasheed Abiola Olajide, Ekpa Emmanuel, Muhibat Komolafe Bolanle & Khadijah Umaru · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2021

In recent times, fluorosis is gradually becoming a severe problem throughout the globe due to toxic effects of fluoride (F) on plants and animals. Natural geological sources and increased industrialization have contributed greatly to the increasing incidence of fluoride-induced h...

Open access Research Article 10.9734/ajrimps/2021/v10i130157