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All published articles 419

Laxative Effects of Aqueous Extract of Sida acuta Leaves in Loperamide- Induced Constipation in Wistar Rats

Nweje- Anyalowu Paul Chukwuemeka, Idakwoji Precious Adejoh, Iserhienrhien Lucky Osafanme, Sheneni Victor Duniya & Momoh Theophilus Boniface · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: To investigate the laxative potentials of aqueous leaf extract of Sida acuta in loperamide-induced constipation in Wistar rats. Methods: Constipation was induced by oral administration of loperamide (3 mg/kg b.wt.). The constipated rats were orally treated daily either with...

Open access Research Article 10.9734/ajrimps/2019/v6i130093

A Study of Correlation of Anthropometric Data with Atherogenic Indices of Students of Rivers State University, Port Harcourt, Nigeria

Ibioku Elekima & Aniekan Inokon · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: The aim of the study was to correlate anthropometric data with atherogenic indices of students in Rivers State University, Port Harcourt as a means of assessing their cardiovascular health. Study Design: A pilot study was carried out in Rivers State University, Port Harcourt...

Open access Research Article 10.9734/ajrimps/2019/v6i130092

Determination of Shelf Life of Picralima nitida, Ciprofloxacin and Pefloxacin Using Bio-Based Concentration-activity Relationship Technique

Kenechukwu Keluo Onyechi & Chinenye Adaobi Igwegbe · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: The shelf-life of Picralima nitida (herbal drug) and two orthodox drugs (ciprofloxacin, and pefloxacin) has been examined. Methodology: The stability studies were carried out using the bio-based concentration-activity relationship technique. Accelerated stability studies wer...

Open access Research Article 10.9734/AJRIMPS/2019/46309

Long-term Consumption of Kola-nut (Cola nitida) Diet Does Not Increase Anxiety Related Behaviour in Mice

S. A. Bisong, C. C. Mfem, C. O. Nku, I. O. Ajiwhen & E. E. Osim · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Following long-term consumption of kola nut (Cola nitida) diet, anxiety related behaviour were studied in 16 Swiss white mice (18-28g body weight). The open field (OF) test, elevated plus maze EPM) and the light/light transition box (LD) tests were used. Swiss white mice were fed...

Open access Research Article 10.9734/AJRIMPS/2019/45797

The Effect of Ethanolic Extract of Tridax procumbens on Potassium Bromate Induced Toxicity in the Kidney of Wistar Rats

J. K. Opara, F. C. Akpuaka & G. U. Ndukwe · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: To investigate the histological effect of ethanolic extract of Tridax procumbens leaf commonly used as medicinal plant, on potassium bromate induced nephrotoxicity in adult Wistar rats. Place and Duration of Study: Department of Anatomy, Faculty of Basic Medical Sciences, Ab...

Open access Research Article 10.9734/AJRIMPS/2018/46121

In vitro Antioxidant and Antimicrobial Activity of Ethanolic Extract of Egg Plant (Solanum melongena Linn) Fruit

Uchendu O. Mbah, Anthony Cemaluk C. Egbuonu, Olorunshola D. Omodamiro, Obinna Jeremiah & Ijere D. Nwanne · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Ethnomedicinal use of plant has been effective in the amelioration of oxidative stress and in the inhibition of pathogenic microorganism. The ethanolic extract of Solanum melongena Linn fruit as a potent in vitro antioxidant and antimicrobial agent was investigated using standard...

Open access Research Article 10.9734/AJRIMPS/2018/45933

Street Children in Port Harcourt Metropolis: Contributory Factors and Challenges They Face

Randy Andy Nsasak, Eme Asuquo & Ibidabo, David Alabere · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Background: Children being on the street for various reasons is a worldwide problem with the phenomenon being more prominent in low- and middle-income countries. Street children exist in categories known as street living children, street working children and street family childre...

Open access Research Article 10.9734/AJRIMPS/2018/46103

Antimicrobial Resistance Profile of Escherichia coli Isolated from Urine of Patients in Nagari Allah Magani Hospital, Keffi, Nigeria

K. O. Eko, S. M. Jodi, I. H. Nkene, R. H. Abimiku, T. Ibrahim & Y. B. Ngwai · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2019

Aim: This study investigated antimicrobial resistance in E. coli recovered from urine of patients attending Nagari Allah Magani Hospital, Keffi, Nigeria. Place and Duration of Study: Department of Microbiology, Nasarawa State University, P.M.B. 1022, Keffi, Nasarawa State, Nigeri...

Open access Research Article 10.9734/AJRIMPS/2018/45728

The Effects of Concomitant Alcohol and Benzodiazepines on the Excitatory and Inhibitory Neurotransmitters and Its Implication in Neuronal Disorders

Antônio José Rocha, Renan Rhonalty Rocha, Francisco Leandro Laurindo de Moraes, Maria Vitória Laurindo & Soraya Lília da Rocha · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Concomitant consumption of ethanol and benzodiazepines (BZDs) play a significant role in the development of tolerance and physical dependence of BZDs. Adaptations within the glutamatergic system in response to prolonged ethanol exposure may in some respects, stimulate the physiol...

Open access Research Article 10.9734/AJRIMPS/2018/45963

The Efficacy and Safety of Primalan (Mequitasine) in the Treatment of Chronic Recurrent Urticaria

Fathi Al-Ballali, Omran Bugrein & Iman Amghaiab · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Objective: To assess the effect of Primalan (mequitazine) in the treatment of chronic recurrent urticaria. Patients and Methods: Twenty four males (57%) and eighteen females (43%) (between ages 22-64 years) were selected, the mean age was 38 years. The disease duration was (4-12...

Open access Research Article 10.9734/AJRIMPS/2018/41871

Reasons for Missed Immunisation among Caregivers of Infants in Rural Communities of Abakaliki in Southeast Nigeria

N. C. Eze · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: Missed immunisation against vaccine preventable diseases is a significant public health problem especially in rural areas of Nigeria. The reasons for missed immunisation are poorly understood. This study, therefore, identified the reasons for missed immunisation in th...

Open access Research Article 10.9734/AJRIMPS/2018/44950

Antihyperglycemic Potential of Ethanolic Extract of Couroupita guianensis on Streptozocin Induced Experimental Diabetic Rat Model

Md. Mynul Hassan, Md. Mahmodul Islam, Shihab Uddin, Amrita Bhowmik & Begum Rokeya · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: The present study was performed to investigate the effect of oral feeding of 50% ethanolic (v/v) extract of Couroupita guianensis leaves in streptozotocin induced type 2 diabetic model rats for the possible anti-diabetic mechanism. Materials and Methods: Water, gliben...

Open access Research Article 10.9734/AJRIMPS/2018/44332

Clinical Outcome Pattern in Diabetic Patients with Complicated Urinary Tract Infections Treated with Ceftriaxone-Sulbactam-EDTA. A Retrospective Study

Mandip Singh Bhatia & Ritu Attri · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Objective: In general, infectious diseases are more frequent and/or serious in patients with diabetes mellitus, complicated further by antimicrobial resistance which potentially increases their morbi-mortality. The objective of this study was to determine the clinical utility of...

Open access Research Article 10.9734/AJRIMPS/2018/44753

Effects of Aqueous Stem Bark Extract of Citrus aurantifolia on the Gastrointestinal Tract of Wistar Rats

Idakwoji Precious Adejoh, Ajima Judith Nnedimkpa, Anosike Joy Chizoba, Amadi Emenike Benjamin & Nweje-Anyalowu Paul Chukwuemeka · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Objective: The anti-diarrhoea activity of the aqueous extract of the stem bark of C. aurantifolia was investigated in this study. Materials and Methods: Acute toxicity evaluation of the aqueous extract of C. aurantifolia stem bark was carried out using rats according to Lorke’s m...

Open access Research Article 10.9734/AJRIMPS/2018/45419

Efficacy of Quadriceps Muscle Strengthening Exercises and Infrared Radiation Therapy in the Management of Symptomatic Knee Osteoarthritis in a South- Eastern Nigerian Population: A Randomised Clinical Study

Ebere Yvonne Ihegihu, Chima Collins Ihegihu, Egwuonwu Afamefuna Victor, Okonkwo Uchenna Prosper & Ativie Rita Nkechi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: Quadriceps strengthening exercises and infrared radiation therapy had been shown to be effective in improving pain, function and quality of life in subjects with knee osteoarthritis (OA). The aim of this study was to determine the efficacy of these modalities of treat...

Open access Research Article 10.9734/AJRIMPS/2018/43999