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All published articles 419

Advanced Glycation Endproducts, (AGEs): Formation, Complication and Pharmacological Evaluation to Its Inhibition

Mohammad Nadeem Khan & Ragini Gothawal · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Glycation commonly known as non-enzymatic glycosylation is the result of sugar molecules binding with a protein or lipid molecule without controlling the action of an enzyme. During the process of glycation, early stage glycation compounds are formed first, which subsequently rea...

Open access Research Article 10.9734/AJRIMPS/2018/40927

Preliminary Assessments and Renoprotective Effects of Methanol Extract of Parquetina nigrescens (African Parquetina) in Diabetic Wistar Rats

O. I. Adeyomoye & E. O. Adewoye · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aim: Phytochemical screening, toxicity and renoprotective effects of methanol extract of Parquetina nigrescens (MEPN) in diabetic Wistar rats were investigated. Methods: Twenty-five rats divided into five groups (n=5) were used for this study. Groups 1 and 2 served as normal cont...

Open access Research Article 10.9734/AJRIMPS/2018/41737

The Assessment of Muscle Relaxation and Anesthesia Depth in Morbidly Obese Patients: Should We Determine Drug doses According to Lean Body Weight (LBW)?

Naciye Ceyda Demir, Nilgün Kavrut Ozturk, Ilkay Bayar, Bilge Karsli & Kerem Inanoğlu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: To give a good planned anesthesia to a morbidly obese patient, it is better to have knowledge about morbid obesity’s interaction and impact on drug dosages. For safe drug dosing, not only increased body weight and changed body composition but also physiological change...

Open access Research Article 10.9734/AJRIMPS/2018/41734

A Comparative Analysis of Patients’ Medicine Price in a Public Tertiary Hospital and Private Retail Community Pharmacy in a Rural Nigerian Community

Roland Nnaemeka Okoro & Chijioke Nmeka · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: One-third of the world’s population lacks access to essential medicines and price of medicine is considered one of the most important obstacles to access. Improving access to quality medicines and treatment is currently the most important strategy to reduce disability...

Open access Research Article 10.9734/AJRIMPS/2018/41764

Assessment Role of Dehydroepiandrosterone (DHEA) and Melatonin or Their Mixture on Physiological and Biochemical Parameters in Alzheimer's Rats Induced by Aluminium Chloride

Mona, I. M. Shahin · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Alzheimer’s disease is progressing neuronal degeneration disease leads to impairment of memory and cognitive ability. It is the most common cause of dementia and its increases with age. the present study was to investigate whether the Dehydroepiandrosterone (DHEA) and Melatonin o...

Open access Research Article 10.9734/AJRIMPS/2018/40465

Infrared Spectroscopy and Microorganisms Associated with African Nutmeg (Monodora myristica) Seeds Sold in a Municipal Market in Imo State, Nigeria

Eberechukwu M. Maduike & Nkiruka C. Anuna · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

This work evaluated the infra-red (IR) spectra of the oil extract from African nutmeg (Monodora myristica) seeds, popularly called ‘ehuru’ in the eastern part of Nigeria – among the Igbos. The microbial analysis of the dried ‘ehuru’ seeds was also carried out in order to ascertai...

Open access Research Article 10.9734/AJRIMPS/2018/40661

Evaluation of Insulin, Malondialdehyde and Blood Pressure in Male Obese Individuals in Nnewi and Subsequent Effect of Green Tea Supplementation

Meludu Samuel Chukwuemeka, Onuora Ifeoma Joy, Dioka Chudi Emmanuel, Obi-Ezeani Chikaodili Nwando & Usman Saheed Opeyemi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: Obesity is a major public health issue worldwide, contributing to increased cardiovascular diseases, diabetes, insulin resistance and oxidative stress. This is due to sedentary lifestyles; poor dieting and low consumption of antioxidant supplement (example green tea)....

Open access Research Article 10.9734/AJRIMPS/2018/41153

Hepatic, Renal, and Anti-oxidant Function Markers Can Improve in Dose-dependent Administration of Fresh Coconut Oil

E. M. Aisuodionoe, O. M. Odigie, A. O. Naiho, M. O. Oyovwi & J. C. Igweh · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Overtime, Oxidative stress has been implicated in the progression of diabetes mellitus (DM) and its related disorders. To this point, several studies posit that antioxidant constituents of virgin coconut oil among others might have a helpful effect in ameliorating diseases. In th...

Open access Research Article 10.9734/AJRIMPS/2018/40811

Questionable International Pediatric Studies in the United States and Russia Triggered by Regulatory Authorities

Klaus Rose & Jane M. Grant-Kels · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: The concept of children as "therapeutic orphans" claims that children were/are denied the use of many modern drugs. Both the United States (US) and the European Union (EU) enacted laws based on this concept. Their regulatory authorities promote industry-sponsored pedi...

Open access Research Article 10.9734/AJRIMPS/2018/40776

Potent Antibiotic to Treat Typhoid Fever in Patients of Pediatric Age-group

Aneeqa Nawaz, Arifa Aslam & Ghina Haq · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aims: To evaluate the safety and effectiveness of Cefixime and chloramphenicol taken orally in the treatment of typhoid fever in pediatric patients. Study Design:  Randomized Clinical Trial. Place and Duration of Study: Department of Pediatric Medicine, DHQ Teaching Hospital, Sah...

Open access Research Article 10.9734/AJRIMPS/2018/41328

Comparative Cost Analysis of Treatment of Bacterial Opportunistic Infections in Patients Living with HIV/AIDS in Two Public Hospitals in Abuja, Nigeria

Paul Otor Onah, Siyaka Abdul Lateef & Ahmed Abdulmalik · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: Bacterial opportunistic infections are the most frequently encountered cause of morbidity and mortality among patients living with HIV/AIDS. There has been a dramatic reduction in mortality related to HIV/AIDS infection following the introduction of highly active anti...

Open access Research Article 10.9734/AJRIMPS/2018/40477

Descriptive Cytological Statistics of Fine Needle Aspiration Cases of Breast Lesions- The Unique Kasr El-Aini Hospital (Cairo University Hospital) Experience

Raba M. Abdalkarim & Tarek R. S. Al Aga · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Background: This study aimed at registering the fine needle aspiration cytology (FNAC) of breast lesion cases received by the pathology department in Kasr El-Aini Hospital (Cairo University Hospital)  in the last 3 years ( Jan 2010 – dec 2012 ). one hundred and three cases were c...

Open access Research Article 10.9734/AJRIMPS/2018/40236

Oral versus Parenteral Iron Supplements: Which is better in Postpartum Iron Deficiency Anemia?

Aneeqa Nawaz, Arifa Aslam & Qurat-Ul-Ain . · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aims: To assess the safety and effectiveness of iron sucrose complex given intravenously versus ferrous sulphate taken orally in the treatment of iron deficiency anemia in the postpartum period. Study Design: Randomized Clinical Trial. Place and Duration of Study: Sahiwal Medical...

Open access Research Article 10.9734/AJRIMPS/2018/40206

Evaluation of Anti-stress Activity of Orthosiphon stamineus Benth. Lamiaceae Aqueous Leaves Extract on Wistar Albino Rats

Krupavaram Bethala, Ragaventhiran Mohan, Shopana Paramasivam, Rama Supriya Veeralla & Anandarajagopal Kalusalingam · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aim: The present study was aimed to determine the in-vivo anti-stress activity of Orthosiphon stamineus aqueous leaves extracts using Wistar albino rats. Methodology: In anoxia stress tolerance test and noise induced stress test Wistar albino rats of either sex was randomly divid...

Open access Research Article 10.9734/AJRIMPS/2018/38132

Antimicrobial Susceptibility Profiles of Pseudomonas aeruginosa Isolates from Patients Attending Health Care Facilities, Ebonyi State, Nigeria

V. U. Olugbue, V. O. Nwaugo, M. O. Okata, M. C. Korie, I. Oko & N. U. Okoro · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2018

Aim: To investigate the antibiotic susceptibility profile of Pseudomonas aeruginosa isolates from wounds of patients and to determine the age group commonly infected with the bacteria. Study Design: This is a cross-sectional study conducted among patients suspected of having woun...

Open access Research Article 10.9734/AJRIMPS/2018/39732