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All published articles 419

Neuroprotective Effect of Lycopene on the Prefrontal Cortex of a Lipopolysaccharide-Induced Rat Model of Alzheimer’s Disease

Bello Abubakar & Timileyin Adeyeye Adewumi · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Alzheimer's disease (AD), the most prevalent form of dementia, is characterized by a progressive decline in memory, thinking, and behavior. Given the absence of a definitive cure for AD, there is an urgent need for accessible therapeutic strategies that can halt or sl...

Open access Research Article 10.9734/ajrimps/2026/v15i2393

Ameliorative Effects of Tetracarpidium conophorum (African Walnut) on Mercury-Induced Pancreatic Dysfunction: A Toxicological, Molecular Docking and Pharmacokinetic Study

Elemuo, Chukwuebuka Stanley, Nwakanma, Agnes Akudo, Elemuo, Michelle Chidimma, Okeke, Jennifer Chioma, Osiagor, Henry Chibueze & Anyiam Kennedy Ekenedirichukwu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Mercury-induced pancreatic dysfunction is primarily driven by oxidative stress, inflammatory signaling, and metabolic dysregulation, underscoring the need for multi-target therapeutic candidates from natural sources. This study evaluated the therapeutic potential of bioactive com...

Open access Research Article 10.9734/ajrimps/2026/v15i2392

Isolation and Identification of Bacterial Contaminants in Selected Soup Thickeners: Achi (Brachystegia eurycoma) and Cocoyam Powder (Colocasia esculenta) from Markets in Enugu Metropolis, Nigeria

Ogechukwu Calista Dozie-Nwakile, Ferdinand Chinwetalu Onwuka, Oluchi Mary Okeh, Eze Anita Chiamaka, Aghatise Kevin Erhamwonyi & Seto Tunrayo Aladenika · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Traditional Nigerian soup thickeners Achi (Brachystegia eurycoma) and cocoyam powder (Colocasia esculenta) are widely consumed yet are often produced, processed, and marketed under conditions of limited hygiene control. Consumer complaints of gastrointestinal disturba...

Open access Research Article 10.9734/ajrimps/2026/v15i2391

Molecular Redesign of Phenylalanine-Arginine-β-Naphthylamide and Biocompatible Efflux Pump Inhibitors for Multidrug Resistant Bacteria: Current Trends and Future Prospects

Ugodi Gerald Walter & Nwachukwu Fortune Udochukwu · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

The escalating global crisis of antimicrobial resistance necessitates innovative therapeutic strategies, with efflux pump inhibitors emerging as a promising avenue to restore the efficacy of existing antibiotics. Multidrug-resistant Gram-negative bacteria pose a significant globa...

Open access Research Article 10.9734/ajrimps/2026/v15i2390

Simultaneous Estimation of Liraglutide and Preservative Phenol in Injectable Dosage Form by Validated Stability-indicating RP-HPLC Method

Shah Yesha Hitesh Kumar & Manisha Kotadiya · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Ensuring the quality and stability of pharmaceutical formulations, especially peptide-based drugs like Liraglutide, requires reliable analytical methods. The simultaneous estimation of active drugs and preservatives using Reverse Phase High Performance Liquid Chromato...

Open access Research Article 10.9734/ajrimps/2026/v15i2389

Phoenix Dactylifera Mitigates Fluoxetine-induced Testicular Toxicity in Rats: Dose-dependent Antioxidant and Anti-fibrotic Effects

Ebenezer Adeola ASHAMU, Adekunle Olabisi Muinat, Taiwo Oluseyi Adebayo, Babalola Abdulazeez Babatunde & Akinyemi Oluwatofunmi Deborah · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Fluoxetine, which is a selective serotonin reuptake inhibitor (SSRI), is commonly prescribed for the treatment of major depressive disorder, anxiety disorders and obsessive-compulsive disorder. Fluoxetine (FLX), a widely prescribed SSRI, induces testicular toxicity, r...

Open access Research Article 10.9734/ajrimps/2026/v15i2387

Assessment of Oxidative Stress Markers in COVID-19 Vaccinated Individuals in Port Harcourt, Rivers State, Nigeria

Uchechukwu Onyemaechi, Uchechukwu Achor Obisike, Onyemaechi Collins Micah & Edna Ogechi Nwachuku · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: The emergence of COVID-19 led to the rapid development and widespread use of vaccines to reduce disease severity and mortality. However, concerns persist regarding vaccine-induced immune responses and their potential effects on oxidative stress and overall health. Aim...

Open access Research Article 10.9734/ajrimps/2026/v15i2388

Recovery after Myocarditis: A Contemporary Literature Review

D. Bennani, B. Lahkim, A. Zouad, M. Joubair, L. Afendi, M. HABOUB & A. DRIGHIL · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Myocarditis is one of the most varied syndromes seen in cardiovascular medicine, being diagnosed as a self-limited inflammatory injury with rapid resolution of symptoms, to fulminant cardiogenic shock, malignant arrhythmias and chronic inflammatory cardiomyopathy, as well as sign...

Open access Research Article 10.9734/ajrimps/2026/v15i2386

Recurrent Cutaneous Lupus Flare with Photosensitivity, Palmar Plantar Hyperpigmented Papules, and Mild Proteinuria Following Abrupt Medication Cessation in a 10 Years Old Boy: A Case of Juvenile Systemic Lupus Erythematosus

Luqman Bin Fahad & Ayesha Mahreen · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Juvenile systemic lupus erythematosus (JSLE) is a rare but aggressive autoimmune disease in children, with boys comprising only 10–20% of cases. Cutaneous manifestations are often the initial or predominant feature, yet atypical palmar-plantar lesions and flares triggered by medi...

Open access Research Article 10.9734/ajrimps/2026/v15i2385

Evaluation of the Effects of Platelet-rich Plasma on Histological Changes Following Experimental Spinal Cord Injury in Wistar Rats

A. Umar, I. Mohammed, J. O. Adisa, M. S. Abubakar, U. F. Abdullahi, F. O. Emetumah, M. S. Sani, M. O. Mohammed, U. Abubakar & J. Noam · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Spinal cord injury (SCI) is a devastating central nervous system disorder that disrupts the structural integrity of the spinal cord causing motor, sensory and autonomic dysfunction leading to permanent paralysis. The aim of this study was to evaluate the effects of platelet-rich...

Open access Research Article 10.9734/ajrimps/2026/v15i2384

Polycystic Ovarian Syndrome: A Leading Cause of Female Infertility

Prakash Chandra Gupta · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

In India, infertility has traditionally been linked to women; though, interestingly, infertility impacts both genders almost equally. The aim of the current study is to explore Polycystic Ovary Syndrome (PCOS) as a significant contributor to female infertility, focusing on its cl...

Open access Research Article 10.9734/ajrimps/2026/v15i2383

Optimising Electrocautery Use in General Surgery: Comparative Performance of Monopolar and Bipolar Systems with Emphasis on Smoke Safety

G. Deivadharani, B. Bharathi & Deepa C. Philip · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Electrocautery remains one of the most ubiquitous and indispensable instruments in the contemporary operating theatre, enabling surgeons to achieve precise tissue dissection and reliable haemostasis across virtually every subspeciality of general surgery. The two principal modali...

Open access Research Article 10.9734/ajrimps/2026/v15i2380

Hypertension-Mediated Left Ventricular Hypertrophy: From Hemodynamic Load to Myocardial Disease

D. Bennani, B. Lahkim, A. Zouad, M. Joubair, L. Afendi, M. HABOUB & A. DRIGHIL · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background: Left ventricular hypertrophy due to hypertension (LVH) is one of the most important cardiac manifestations of chronic hypertension and is strongly associated with heart failure, atrial fibrillation, stroke, and death. While traditionally thought of as an adaptive resp...

Open access Research Article 10.9734/ajrimps/2026/v15i2381

Evaluation of the Management of Drug-Resistant Pulmonary Tuberculosis at the Matam Tuberculosis Center, Conakry, Guinea

Bilengbe Delamou, Ahmadou Sadio Diallo, Bernadette Goualie & Demba Magassouba · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Background and Aims: Tuberculosis remains a major public health problem, and the emergence of drug-resistant forms significantly complicates its management, particularly in resource-limited countries such as the Republic of Guinea. Thus, this study is to assess the management of...

Open access Research Article 10.9734/ajrimps/2026/v15i2382

Hormonal Contraception and the Risk of Pulmonary Embolism in Women of Reproductive Age: A Narrative Review with Clinical Perspectives

D. Bennani, B. Lahkim, L. Afendi, F. Essadqi, A. El Bouazizi, M. HABOUB, M. BOUZIANE & A. DRIGHIL · Asian Journal of Research in Medical and Pharmaceutical Sciences · 2026

Pulmonary Embolism (PE) remains a relevant source of morbidity in women of reproductive age, although it is often unrecognized. Hormonal contraception is a well-established acquired risk factor for PE because of its association with venous thromboembolic events; however, it has v...

Open access Research Article 10.9734/ajrimps/2026/v15i2379