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All published articles 245

Total and Differential White Blood Cell Counts among Women Using Oral Contraceptives in Owerri, Southeastern Nigeria: A Comparative Cross-sectional Study

O. Nwaiwu Divine, Aloy-Amadi Oluchi Chinwe & Tamunonengiye-Ofori Lenox-Prince · International Journal of Research and Reports in Hematology · 2026

Background: Oral contraceptives are widely used for family planning, yet their relationship with                circulating leukocyte patterns is not fully understood and may differ according to population and hormonal formulation. Objective: To compare total and differential whi...

Open access Research Article 10.9734/ijr2h/2026/v9i2247

C-Reactive Protein and Routine Coagulation Studies in Obstetric Patients with and without Recorded Clinical Complications in Ibadan, Nigeria

Olajumoke Gbemisola Ajayi, Festus Olatubosun Amusan, Tolani Jamiu Ojo, Beatrice Ebun Adesina, Bukunmi Kehinde Bamidele & Wemimo Taiwo Bamidele · International Journal of Research and Reports in Hematology · 2026

Background: Pregnancy alters inflammatory and haemostatic profiles, complicating the interpretation of routine laboratory measurements. Aim: This study compared C-reactive protein (CRP), prothrombin time (PT) and activated partial thromboplastin time with kaolin (aPTTK) in obstet...

Open access Research Article 10.9734/ijr2h/2026/v9i2246

Neurobehavioral and Hematological Effects of Zapoteca portoricensis (Jacq.) H.M.Hern Root Ethylacetate Fraction against Scopolamine Induced Cognitive Impairment in Rats

Felix Keneolisa Asogwa, Augustine Oluchukwu Asogwa, Daniel Lotanna Ajaghaku, Jude Ibeabuchi Ali, Faustina Chidiebere Udeozo & Sylvia Amarachi Ojobor · International Journal of Research and Reports in Hematology · 2026

Background: Alzheimer’s disease (AD) is a neurodegenerative disorder characterised by progressive dementia, neuroinflammation, and the accumulation of intracellular neurofibrillary tangles and extracellular amyloid plaques. Oxidative stress and cholinergic dysfunction are key con...

Open access Research Article 10.9734/ijr2h/2026/v9i2244

Evaluation of Selected Hematological and Biochemical Parameters among Hypertensive Subjects Attending the Federal Medical Centre, Yenagoa, Nigeria

Ogechi Orluowhor, Benjamin Eledo & Richard Eze · International Journal of Research and Reports in Hematology · 2026

Background: Hypertension is a major cardiovascular risk factor that may be associated with alterations in cardiac biomarkers, haematological parameters, lipid metabolism, vascular function, and inflammatory responses. Assessing haematological and biochemical parameters may theref...

Open access Research Article 10.9734/ijr2h/2026/v9i2245

Haematological and Peripheral Blood Smear Response to Two Months of Oral Iron Therapy in Anaemic Adult Females: A Paired Study from West Tripura, India

Anchal Saha, Suman Kalyan Nath & Prabal Krishna Majumder · International Journal of Research and Reports in Hematology · 2026

Background: Anaemia is a common health problem among women of reproductive age. Local studies from Tripura have reported anaemia in young women and have highlighted the possible contribution of menstrual and nutritional factors. This study evaluated haematological parameters and...

Open access Research Article 10.9734/ijr2h/2026/v9i2243

Chronic Haemolytic–inflammatory Activation Persists beyond Clinical Crisis in Adults with Sickle Cell Anaemia: A Comparative Cross-sectional Study

Adeyanju Oluwaseyi Adeteju, Festus Olatubosun Amusan, Beatrice Ebun Adesina, Richard Peter Akpan, Akanbi Mitchelle, Adewale Adetunji Oladapo, Adeyanju Adebukola Temilade & Olusegun Taiwo Oke · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell anaemia is characterised by chronic haemolysis and inflammation. Whether these processes persist during clinically stable periods or are mainly associated with painful crises remains unclear in the local literature. Objective: To compare lactate dehydrogen...

Open access Research Article 10.9734/ijr2h/2026/v9i2242

Prevalence of B-Thalassemia Trait among Individuals Undergoing Premarital Screening in Anbar Province

Mohammed Sabah Dawood, Rafi Khaleel Al-Ani & Ismail Khaleefah Nawaf · International Journal of Research and Reports in Hematology · 2026

Background: β-thalassemia is a significant hereditary haematological disorder with a high prevalence in Iraq. Premarital screening is a critical preventive strategy for identifying couples at risk of having children with thalassemia major. This is the first study conducted in Anb...

Open access Research Article 10.9734/ijr2h/2026/v9i2241

Oxidative Stress, Antioxidant Defense and Trace Element Alterations in Sickle Cell Disease during Vaso-Occlusive Crisis and Steady State

Temitope Oyewole Olusanya, Samuel Oluwatamilore Osubu, Toluwani Sikemioluwa Oyewo, Ayomide Motunrayo Banjo, Kamsiyochukwu Victoria Ife, Owokalade Princess Adekunbi & Abiodun Oluwasegun Adetola · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell disease (SCD) is associated with chronic haemolysis, inflammation and recurrent vaso-occlusive crises (VOC), with oxidative stress contributing to its pathophysiology. However, the interplay among oxidative stress, antioxidant defences and trace element st...

Open access Research Article 10.9734/ijr2h/2026/v9i2240

Leukocyte Differential Distribution and Creatine Kinase Elevations as Indicators of Tissue Stress and Inflammation in Sickle Cell Disease

M. M. Akanbi, R. P. Akpan, F. O. Amusan, B. E. Adesina, A. O. Adewale, O. A. Adeyanju & Akanbi Kayode · International Journal of Research and Reports in Hematology · 2026

Aims: To evaluate leukocyte subset distribution and serum creatine kinase (CK) activity, considered jointly, as indicators of tissue stress and low-grade inflammation in Nigerian patients with sickle cell anaemia. Study Design: A hospital-based, cross-sectional comparative study....

Open access Research Article 10.9734/ijr2h/2026/v9i2239

Evaluation of Some Inflammatory Markers of Malaria Infected Subjects in Port Harcourt, Nigeria

Sarah Ibinye Wilcox, Evelyn Mgbeoma Eze & Stella Urekweru Ken-Ezihuo · International Journal of Research and Reports in Hematology · 2026

Malaria is a highly inflammatory disease characterised by periodic fever, headache, and nausea, which correspond to the rupture of infected erythrocytes and the release of merozoites that replicate within the host to produce newly formed daughter parasites. The aim of this study...

Open access Research Article 10.9734/ijr2h/2026/v9i2238

Serum Vitamin B12 and Creatine Kinase Status and Their Relationships with Haematological Parameters in Nigerian Sickle Cell Anaemia Patients

M.M. Akanbi, R.P. Akpan, F.O. Amusan, B.E. Adesina, A.O. Adewale, O.A. Adeyanju & Akanbi Kayode · International Journal of Research and Reports in Hematology · 2026

Aims: To determine serum vitamin B12 and creatine kinase levels and to establish their relationships with selected haematological parameters among patients with sickle cell anaemia attending a tertiary hospital in southwestern Nigeria. Study Design: A cross-sectional comparative...

Open access Research Article 10.9734/ijr2h/2026/v9i2237

Bilateral Peripheral Ulcerative Keratitis with Corneal Perforation Revealing Acute Myeloid Leukaemia in a Young Adult: A Case Report

Lotfi Chaabani, Ines Bouallegui, Mohamed Said & Yosra Hamdi · International Journal of Research and Reports in Hematology · 2026

Background: Peripheral ulcerative keratitis (PUK) is a destructive corneal disorder that may progress rapidly to perforation and can occasionally indicate serious systemic disease. Aim: To report a rare and clinically important case of bilateral peripheral ulcerative keratitis (P...

Open access Research Article 10.9734/ijr2h/2026/v9i2236

Full Blood Count Platelet Parameters in Sickle Cell Disease: A Systematic Review of Thrombocytosis, Thrombocytopenia, and Clinical Implications

Jacques Forwah Ndeh, Edung Emen Samuel, Ofonime Benjamin Essien, Bassey Okon Bassey, Mansurat Oluwasshola Alabi, Ihuoma Fidelia Onunaku, Joy Oyemwen Aikpitanyi, Diderot Tiemen Charles, Ewa Anthony Obi, Idiege Idiege Omang, Edomaruse Maxwell Joseph, Alu Owere Emmanuel, Prince-Nnabugwu Ruth Amarachukwu, Adegboyega Akintola, Asuquo Ukemeobong Michael, Maduka Ekene Ekezie, Gbeminiyi Ebenezer Adekanmbi, Ike-Ogbonna Ginikachi Valerie, Agbayewa Ademola, Chioma Kenis Onyejekwe, Oluwatobiloba Akinwale, Egwowa M. Elo-Oghene, Bushirat Mulero, Sally Tsagli, Abdullah Damilare Shonola, Oyibo Basil Eze, Princess Adebanwi, Akaba Kingsley Onoridea, Nnaji Chimuanya Joseph, Ushie Godwin Abua, Immaculate Ihuoma Ekeagba, Tams Isaac Tamunobelema & Abeshi Sylvester Etenikang · International Journal of Research and Reports in Hematology · 2026

Background: Sickle cell disease (SCD) is characterized by chronic hemolysis, endothelial dysfunction, and systemic inflammation, each of which disrupts platelet homeostasis. The full blood count (FBC), the most universally available hematological test, remains underutilized in ro...

Open access Research Article 10.9734/ijr2h/2026/v9i2235

Automated Haematology in Infectious Disease Diagnosis and Management: A Critical Review with Special Reference to Nigeria

Erens Spiff Ekprikpo · International Journal of Research and Reports in Hematology · 2026

Automated haematology analysers have transformed the way clinicians detect, monitor, and manage infectious diseases, moving the complete blood count from a slow manual procedure into a rapid, multi-parameter diagnostic platform. This review examines the technological evolution of...

Open access Research Article 10.9734/ijr2h/2026/v9i2234

Effect of Methanolic Leaf Extract of Ficus capensis on Iron Status Biomarkers in Phenylhydrazine-induced Anaemic Wistar Rats

Isaiah Audu, I. K. Kwaifa, F. U. Onuigwe, H. M. Alhassan & U. Abubakar · International Journal of Research and Reports in Hematology · 2026

Iron deficiency anaemia (IDA) is a condition characterised by a decrease in the number and size of red blood cells, leading to inadequate oxygen delivery to tissues and organs. It is the most common nutritional disorder worldwide, affecting approximately 1.6 billion people global...

Open access Research Article 10.9734/ijr2h/2026/v9i2232