Background: Traditionally, the use of Xylopia aethiopica fruit for therapeutic purposes is on the increase without any consideration of its safety and toxicity. Aim: This study was therefore designed to examine its effect on coagulation factors of Wistar rats. Methodology: The fr...
Chronic myeloid leukaemia (CML) is now more than ever the model for targeted treatment in human cancers. The success of imatinib and second-generation tyrosine kinase inhibitors (TKIs) has significantly improved the prognosis of CML patients. Because TKI-treated CML patients have...
Maintenance of hemostasis is enabled by the presence of nonnucleated blood cell type known as platelets, produced by the cellular fragments of megakaryocytes. Platelet count below <150,000×103/mm3 can pave way for the occurrence of thrombocytopenia. Occurrence of thrombocytope...
Sickle cell anaemia (SCA) is the most common genetic disease in the world, with Sub-Saharan Africa bearing the heaviest burden. Despite the availability and known benefits of hydroxyurea, its use in low- and middle-income countries has been limited. The purpose of this study was...
The aim of this study was to determine the effect of consumption of Campus Buka Diets on some health indicators of apparently healthy students of Abia State University, Uturu. A total of 350 students were randomly selected from the various faculties that constitute the university...
Hypertension is a major health issue that affects people all over the world. It can cause cardiovascular illness as well as functional issues, such as alterations in haematological parameters. At the Federal Medical Centre in Owo, Ondo State, the goal of this study was to analyse...
Background: Citrus aurantium L. (Rutaceae), commonly known as bitter orange is widely consumed owing to its numerous therapeutic potentials. Purpose: This study evaluated the impact of Citrus aurantium fruit (bitter orange) juice on bodyweight and haematological parameters of wis...
Aims: Knowledge of Rh phenotype frequencies guides in assessing the probability of Rh alloantibody formation and finding Rh-negative antigen donors. There is limited information on the RhCE phenotypes and probable genotype frequencies among D negative Omani population, hence thi...
Obu Sylvia Ifeoma, Asiodu Anthony Uchenna, Osiatuma Victor Azubuike, Ojimba, Anastacia Okwudili, Oburo Ngozichukwuka Andrew, Iyasele Anthony Chukwuemeka, Nnanna Tochi Praise, Aigbokhaode Adesuwa, Dibigbo-Ibeaji Ndudi, Jisieike Obianuju Nkemjika, Edet Samuel Eno & Sadoh Odion Rosemary·International Journal of Research and Reports in Hematology·2022
Aims: To assess some haematological parameters and indices of hospitalized COVID-19 infected patients treated during the first wave of the pandemic in the Centre for Communicable Disease Control and Research (CCDCR) Federal Medical Centre Asaba, Delta State, Nigeria. Study Design...
Introduction: Pregnancy is associated with alterations in haematological and oxidative stress parameters as physiological adjustments are made to accommodate the increasing demand from the fetus and the maintenance of maternal wellbeing. No study has evaluated the interaction bet...
Aims: RHD gene analysis performed directly from repeatedly extracted DNA on FTA card disc has not been studied. Here we demonstrate a direct real-time PCR of RHD gene exon 10 by reusing FTA card. Study Design: This is an experimental pilot study to observe the RHD exon 10 amplifi...
Anti-pyretic effect of aqueous leaf extract of Alchornea cordifolia on Wistar rats were investigated. Twenty Wistar rats of both genders weighing between 110-178g were used for this study. Baker’s yeast was used for induction of pyrexia. The rats were grouped into five groups of...
Introduction: Sickle cell disease (SCD) is caused by mutation in the β-globin, which results in gene substitution of Valine for Glutamic acid. SCD is prevalent in Plasmodium falciparum endemic regions such as Nigeria. Thus, haematological parameter of SCD patients during malaria...
Rituximab is a monoclonal antibody against CD20 a leucocyte cell marker expressed on normal and neoplastic B lymphocytes .Although first used for treatment of CD20 positive non-hodgkin’s lymphoma it’s use has expanded to include a varied spectrum of diseases mostly autoimmune dis...
COVID-19 is a viral infectious disease that is thought to have emerged from an animal market in Wuhan, People's Republic of China, in December 2019, and subsequently caused a pandemic. Despite the fact that one year has passed since the onset of the epidemic and many treatment ag...