Aim: To determine the relationship between folate status and CBC parameters in SCA patients at steady state. Study Design: Comparative cross-sectional study. Setting: Departments of Haematology and Blood Transfusion and Paediatrics, Aminu Kano Teaching Hospital, Kano, Nigeria bet...
Background: Methemoglobin (Hi) is a metaloprotein in which the iron in the haem group is in ferric state. Sulphaemoglobin (SHb) is a stable, green- pigmented molecule, which is made by the oxidation of the iron in haemoglobin to a ferric state by drugs and chemicals that contain...
This review discusses the implication of sugar intake in haemorrhoid and menstruation. Haemorrhoid is the clustering of veins in the rectum leading to swollen anus. This occurs due to pressure exerted on the rectum. When these veins swell, they expand outward into the membranes a...
Introduction/Aim: Haemophilia is a rare X chromosome linked inherited bleeding disorder, characterized by deficiency of coagulation factor VIII in Haemophilia A or factor IX in Haemophilia B. Patients deficient of either of these coagulation factors are prone to fracture as a res...
Reportedly transmitted through unprotected sexual intercourse with infected person(s), experts have estimated new cases of hepatitis B virus (HBV) infections to be over 70,000 per year in the United States. With little or no records of such in Nigeria, this study investigated the...
Herbal preparations continue to be the mainstay of treatments for diverse medical conditions worldwide especially in sub-Saharan Africa and other resource-constrained areas. The preparations are often taken for a prolonged period due to the chronic nature of some of the medical c...
Background: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm (MPN) that originates in an abnormal pluripotent stem cell [1]. At diagnosis, all cases of CML have the characteristic t(9;22) translocation that results in the Ph chromosome [2]. Marked bone marrow (BM)...
Background: Sickle cell disease is a condition in which an individual inherit two abnormal haemoglobin genes from both parents βs/βs (HbSS) resulting in pathological state which is attributed to the sickling phenomenon, vaso-occlusion crises, infection and other complications. Ab...
This study investigated the effects of ethanolic extract of Anacardium occidentale on paracetamol induced liver toxicity in Wistar rats. Twenty (20) Wistar rats were randomly divided into four (4) groups of five (5) rats each. The groups were designated as follows; A, B, C and D....
In medical practice, examination of blood for the presence of metabolites and other constituents is vital to the prediction of the physiological, nutritional and pathological status of any individual prior to prognosis. This study investigated the effect of crude n-hexane stem ex...
Introduction: Iron deficiency anemia is a common disease prevalent mostly in developing countries Replenishing iron stores via oral route supplementation takes longer time, however for safety reasons it is considered as the most convenient route. There is always search of better...
Ibrahim Alkasoum, Maman Daou, Mahamadou Doutchi, Samaila Boubacar, Mansour Maman Anou, Mahamane Moustapha Lamine, Ramatoulaye Hamidou Lazoumar, Kamayé Moumouni, Djibo Yacouba Hamadou & Ibrahim Maman Laminou·International Journal of Research and Reports in Hematology·2019
Summary: Problem: Malnutrition and malaria are responsible for high mortality rate in Niger. The interaction between malnutrition and malaria remains controversial. Methodology: We analyzed the retrospective data (2014 and 2015) of malarious children referred to the pediatric dep...
Background: Advanced liver disease is commonly associated with complex haemostatic defects that include impaired synthesis of clotting factors and coagulation inhibitors in association with thrombocytopenia and platelets defects. Aim of the Study: It was designed to determine whe...
Iron deficiency anaemia is commonly associated with thrombocytosis, however cases of thrombocytopenia have been reported. Recurrent cases of iron deficiency with thrombocytopenia are even more unusual; therefore, we present a patient with recurrent thrombocytopenia in the setting...
Aim: To assess the serum levels of pro-inflammatory cytokines in children with sickle cell disease in steady- state and vaso-occlusive crises in comparison to healthy children of the genotype HbAA. Study Design: Case-Control study Place and Duration of Study: University of Port H...