The KRAS G12V mutation is a formidable oncogenic driver implicated in the pathogenesis of several aggressive cancers, including pancreatic ductal adenocarcinoma, non-small cell lung cancer, and colorectal cancer. Overcoming the historical challenges associated with targeting KRAS...
Open access
Research Article10.9734/ijbcrr/2025/v34i2978
Quinoxalines are nitrogen-rich heterocyclic compounds that have attracted a lot of attention in scientific research because of their important biological activities and multifaceted functionalization capabilities. The study's scope includes their use as powerful antiviral agents,...
Open access
Research Article10.9734/ijbcrr/2025/v34i3979
Background and Objectives: Sesame (Sesamum indicum) is one of the earliest human production and consumptioncrops in the family of Pedaliaceae. It is also an erect annual herb that grows 60–150 cm tall, having simple or branched stem, andwith leave oppositeor alternately at each n...
Open access
Research Article10.9734/ijbcrr/2025/v34i2977
Chantal Yah Kouamé-Dia, Carine Yao-Yapo, Kadio Morel Kouacou, Jean Louis Konan, Bénédicte Koné-Dakouri, Akissi Joelle Koffi, Minhibo Pohosson, Otchoumou Bétina, Fatou Koné-Koné, Eric Sagou Yayo, Angèle Edjème-Aké, Hugues Ahiboh & ML Hauhouot-Attoungbré·International Journal of Biochemistry Research & Review·2025
Background: Long known for its role in phosphocalcic metabolism, vitamin D has been attracting growing interest in recent years for its involvement in numerous physiological processes, including its essential role in reproductive health. According to many authors, vitamin D is in...
Open access
Research Article10.9734/ijbcrr/2025/v34i2976
Arsenic toxicity has been linked to liver cancer and medicinal plants are possible sources of antidote to arsenicosis. Andrographis paniculata (AP), generally known as king of bitters has various pharmacological as well as medicinal properties. In the present study, the protectiv...
Open access
Research Article10.9734/ijbcrr/2025/v34i2974
Introduction: Sphenostylis marginata is a plant in the family Fabaceae and native to many parts of Africa. It is used as a wild vegetable, in folk medicine, as a fetish plant, food additive, and for harvesting fish. Small-scale fishermen in selected parts of Zambia use the crushe...
Open access
Research Article10.9734/ijbcrr/2025/v34i2975
Piliostigma thonningii (Schumach Mile-Redh) is a species of the Fabaceae family. In Côte d'Ivoire, the young, unopened leaves of this species are used to treat certain pathologies. The aim of this study was to determine the compounds present in the ethyl acetate fraction of young...
Open access
Research Article10.9734/ijbcrr/2025/v34i2973
AMP-activated protein kinase (AMPK) is an important enzyme that plays a critical role in cellular energy metabolism. By activating AMPK through diet, lifestyle, and supplement strategies, individuals can improve their glucose and lipid metabolism, promote mitochondrial function a...
Open access
Research Article10.9734/ijbcrr/2025/v34i2972
A survey for the rot of apple fruits sold in two markets of Mubi North Local Government, Adamawa State (Mubi Main Markets and Mubi New Markets) was conducted between June and September 2023. Also, the in vitro effect of ginger (Zingiber officinale) aqueous and ethanolic root extr...
Open access
Research Article10.9734/ijbcrr/2025/v34i2971
This study carried out the mathematical evaluation of heavy metals and polycyclic aromatic hydrocarbons in selected commonly consumed seafood and health risk implications in akipelai town, Ogbia, Bayelsa State. Seafood were collected from Akepelai River. Heavy metals, PAHs, estim...
Open access
Research Article10.9734/ijbcrr/2025/v34i2970
The selection of appropriate mutant and immunodeficient mouse strains is paramount in biomedical research, significantly impacting the validity and translatability of experimental findings. This systematic review examines key mouse strains frequently employed in immunological and...
Open access
Research Article10.9734/ijbcrr/2025/v34i2968
Vegetables are fresh parts of plants which either raw, cooked, canned or processed in any other form, provide suitable human nutrition. This study was aimed at evaluating the nutrient composition of some red vegetables. Radish, Rhubarb, Strawberry, Beetroot and Red cabbage sample...
Open access
Research Article10.9734/ijbcrr/2025/v34i2969
Introduction: Potentially harmful substances contaminating agricultural soil and crops pose a risk to human health and food safety. One of the main elements causing pollution in agriculture is heavy metals. Heavy metals can be found in cereal grains including rice, which absorb a...
Open access
Research Article10.9734/ijbcrr/2025/v34i2967
Oniye Adesola Helen, Ariwoola Bright Shariah, Adesina Beatrice Ebun, Amusan Festus Olatunbosun, Inegbenebor Sylvester Ehilenbalu, Akpan Richard Peter & Alabi Raphael·International Journal of Biochemistry Research & Review·2025
Introduction: A leading cause of cardiovascular disorders and metabolic dysregulation, hypertension continues to pose a serious threat to global health. Urbanization, dietary changes, and sedentary lifestyles are some of the factors contributing to the rising prevalence of hypert...
Open access
Research Article10.9734/ijbcrr/2025/v34i2966
The Ivorian flora is rich in plants of interest, some of which are used to treat neurodegenerative diseases. Among them, Nauclea latifolia (NL), Bombax costatum (BC) and Vernonia cinerea(VC) were studied for their potential. This qualitative research focuses on the phytochemical ...
Open access
Research Article10.9734/ijbcrr/2025/v34i2965