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All published articles 1167

Oral Acute & Sub-Chronic Toxicity Assessment of Ethanol Leaf Extract of Simarouba glauca

Sammydavies E. Osagie-Eweka, Noghayin E. J. Orhue, Eric K. I. Omogbai & Fabian O. Amaechina · International Journal of Biochemistry Research & Review · 2020

Traditional herbal medicine and their preparations have been widely used for thousands of years and are still in use in developing and developed countries owing to their medicinal values and their presumed relative safety. This belief that medicinal plants are not toxic or are wi...

Open access Research Article 10.9734/ijbcrr/2020/v29i830215

Correlation between Serum Sodium and Potassium Levels in Preeclampsia

Sneha Saha, Yanglem Ajitkumar Singh, Sangeeta Naorem, Racheal Sweet Marbaniang, Victoria Kshetrimayum, Tina Das, Potsangbam Jenny Devi & Medowelie Mathew · International Journal of Biochemistry Research & Review · 2020

Aims: The aim of this study was to find the correlation between serum sodium and serum potassium with preeclampsia. Study Design: This is a cross sectional study. Place and Duration of Study: Conducted in Department of Biochemistry in collaboration with the Department of Obstetri...

Open access Research Article 10.9734/ijbcrr/2020/v29i830214

The Proximate Composition and Anti-nutritive Content of Cnidoscolus aconitifolius Leaves

H. M. Adamu, Paidayi Gabriel Bara & O. A. Ushie · International Journal of Biochemistry Research & Review · 2020

The nutritional composition, mineral content as well as anti-nutritional of Tree spinach (Cnidoscolus aconitifolius) leaves were investigated using standard methods. The results of the investigation showed the presence of moisture to be 5.64±0.30%, ash- 9.27±0.16%, crude protein-...

Open access Research Article 10.9734/ijbcrr/2020/v29i830213

The Staining Interactions of Aqueous Extract of Skin Allium cepa (Red Onion) on Some Selected Histological Tissues

M. O. Mohammed, A. A. Hali, O. O. Okechi, A. T. Muhammad, R. I. Tsamiya, U. Abubakar, I. Mohammed, A. Umar, S. M. Sani, M. K. Dallatu, J. M. Bunza, H. Kabir, H. M. Tambuwal, A. Slisu, B. A. Bello, F. A. Dogondaji, N. Okorie, S. Y. Ma’aruf, D. Isah, A. A. Ngaski, N. A. Idris, A. S. Ajayi, M. Isah, M. Sirajo, A. Abdulazeez & H. Abullahi · International Journal of Biochemistry Research & Review · 2020

Introduction: Histological stains are biological dyes which colour tissue in order to aid optical differentiation of tissue component. Dyes are coloured substance which impact colour for material such as textile, cosmetic, food, drugs, rubber plastics, hair, fur and tissues. Ther...

Open access Research Article 10.9734/ijbcrr/2020/v29i830212

Characterisation and Hypolipidaemic Activity of Phenylquinoline, and Narceine Isolated from Ficus polita Leaf

A. Nasir, M. S. Sule, A. J. Alhassan, M. K. Atiku, Y. Y. Muhammad, A. Idi, I. U. Muhammad, A. I. Yaradua, K. I. Matazu & M. B. Isah · International Journal of Biochemistry Research & Review · 2020

Aim: To evaluate hypolipidaemic potentials of column chromatography fractions (F1 to F6) of the chloroform leaf extract of Ficus polita and to detect the bioactive compounds present in the most active fraction using spectroscopic techniques. Study Design:  Fourty-five (45) wistar...

Open access Research Article 10.9734/ijbcrr/2020/v29i830211

The Potential Use of Blood, Cerebrospinal Fluid, Saliva and Urine as Biological Samples for the Diagnosis of Alzheimer’s Disease

Adnan Awn Algarni, Abdulhadi I. Bima & Ayman Z. Elsamanoudy · International Journal of Biochemistry Research & Review · 2020

Background and Aim: Alzheimer’s disease (AD) is the most common cause of dementia. 80% of all dementia is due to AD. Diagnosis of AD is a difficult task, as the accurate diagnosis requires post-mortem examination of brain autopsy samples. Diagnosis of AD in living individuals can...

Open access Research Article 10.9734/ijbcrr/2020/v29i830210

Phenolic Content, Antioxidant Activity, 15-Lipoxygenase and Lipid Peroxidase Inhibitory Effects of two Medicinal Plants from Burkina Faso: Acacia macrostachya Reich. Ex Benth (Mimosaceae) and Lepidagathis anobrya NEES (Acanthaceae)

Adjaratou C. Coulibaly, W. L. M. Esther B. Kabre, Mariam N. Traoré, Tata K. Traore, Nouhoun Nignan, Noufou Ouedraogo, Martin Kiendrebeogo & Richard W. Sawadogo · International Journal of Biochemistry Research & Review · 2020

Acacia macrostachya (Mimosaceae) and Lepidagathis anobrya (Acanthaceae) are two medicinal plants used in Burkina Faso folk medicine for the treatment of inflammatory diseases. The purpose of this study was to assess the phenolic content, the antioxidant, lipoxygenase and lipid pe...

Open access Research Article 10.9734/ijbcrr/2020/v29i830209

In silico Anti-malaria Activity of Quinolone Compounds against Plasmodium falciparum Dihydrofolate Reductase (pfDHFR)

Toheeb A. Balogun, Damilola A. Omoboyowa & Oluwatosin A. Saibu · International Journal of Biochemistry Research & Review · 2020

Chemotherapy remains the kernel of malaria control and the available antimalarial drugs are not only expensive but also parade heterogeneous levels of toxicity and may invoke poor compliance in patients. The present study focuses on the screening of quinolone compounds against Pl...

Open access Research Article 10.9734/ijbcrr/2020/v29i830208

Therapeutic Effects of Aqueous and Ethanolic Extracts of Phyllanthus amarus on 1, 2 Dimethylhydrazine Induced Colon Carcinogenesis in Balb/C Mice

F. O. Omoregie, G. E. Eriyamremu & Suman Kapur · International Journal of Biochemistry Research & Review · 2020

Context: Phyllanthus amarus is traditionally used for various infections, inflammation and cancer. 1,2 Dimethylhydrazine is a potent colon cancer inducer in animals. Objective: The present study investigated the effects of aqueous and ethanolic extract of Phyllanthus amarus on 1,...

Open access Research Article 10.9734/ijbcrr/2020/v29i730206

Protective Effects of Aqueous and Hydroethanolic Extracts of Secamone afzelii (Asclepiadaceae) Leaves on Liver Transaminases, Serum Vitamin D and Zinc Levels against Carbon Tetrachloride (CCl4)- Induced Hepatotoxicity in Rats

Koné Djoudori Serge, Gnahoue Goueh, Djyh Bernard Nazaire, Bamba Abou & Yapi Houphouet Felix · International Journal of Biochemistry Research & Review · 2020

Purpose: This study was carried out to evaluate effect of aqueous and hydroethanolic extracts of Secamone afzelii leaves on Liver transaminases, serum vitamin D and Zinc levels in hepatotocixity induced by carbon tetrachloride (CCl4) in rats. Methods: The experiment was performed...

Open access Research Article 10.9734/ijbcrr/2020/v29i830207

Phytochemicals and Vitamin Properties of Smoothie Flavoured with Mint Leaves Extract

A. T. Victor- Aduloju, N. M. Nwanja, C. C. Ezegbe, K. S. Okocha & T. A. Aduloju · International Journal of Biochemistry Research & Review · 2020

This study was undertaken to assess the phytochemicals, vitamin A and vitamin C properties of different samples of smoothie produced from mixed tropical fruits flavoured with mint leaves extract. The smoothie was produced from three different fruits, (watermelon, apple and banana...

Open access Research Article 10.9734/ijbcrr/2020/v29i730203

Level of Some Mineral Elements in Zobo (Hibiscus sabdariffa) Drink Consumed within Gombe Metropolis

S. M. Umar, F. U. Maigari, J. J. Idi & J. Salome · International Journal of Biochemistry Research & Review · 2020

The study was conducted to determine the levels of magnesium, phosphorus, potassium and calcium present in Zobo Drink consumed in Gombe metropolis. Zobo (Hibiscus sabdariffa) drink has been consumed for decades as a non-alcoholic beverage, thus, the knowledge of its nutritional v...

Open access Research Article 10.9734/ijbcrr/2020/v29i730205

Serum Levels of Adenosine Deaminase and Insulin in Type 2 Diabetes Mellitus

Yengkhom Upen Singh, Sangeeta Noarem, Potsangbam Jenny Devi, Victoria Kshetrimayum, Racheal Sweet Marbaniang, Uma Debbarma, Ksh. Birendra Singh & Maisnam Amuba Singh · International Journal of Biochemistry Research & Review · 2020

Aim: To estimate the levels of serum adenosine deaminase and insulin in patients with type 2 diabetes mellitus and healthy subjects and to find the correlation between serum adenosine deaminase and serum insulin in type 2 diabetes mellitus. Study Design: Case-control study. Place...

Open access Research Article 10.9734/ijbcrr/2020/v29i730202

Evaluation of Serum Uric Acid, Serum Magnesium and Lipid Profiles in Type 2 Diabetes Mellitus Patients for the Risk Factor of Cardiovascular Disease

Sonal Sogani, Navendru Kumar Gupta & Suman Jain · International Journal of Biochemistry Research & Review · 2020

Background and Objective: Dyslipidemia is one of the common disorders which are seen in most of the diabetes patients, which causes cardio vascular diseases. However, serum uric acid and lipid profiles are considered as the potential risk factor for developing diabetes, hypertens...

Open access Research Article 10.9734/ijbcrr/2020/v29i730201

Comparative Analysis of the Phytochemicals, Proximate and Mineral Compositions of Scent Leaf (Ocimum gratissimum) and Bitter Leaf (Vernonia amygdalina) Leaves

Nkoli M. Mgbemena & Ngozi F. Amako · International Journal of Biochemistry Research & Review · 2020

Ocimum gratissimum (fam.Lamiaceae) ‘Scent leaf’ and Vernonia amygdalina (fam.Asteraceae) ‘Bitter leaf’ are commonly consumed vegetables in Southern Nigeria. O. gratissimum is used by the ‘Igbos’ of South East Nigeria to flavor soups and stews while it is popular with the ‘Yorubas...

Open access Research Article 10.9734/ijbcrr/2020/v29i730200