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All published articles 1167

Efficacy of Securidaca longipedunculata Fresen (Polygalaceae) against Two Standard Isolates of Neisseria gonorrhoeae

Wekesa Euginia Makinia, Michaiah Ojunga & Z. Ngalo Otieno- Ayayo · International Journal of Biochemistry Research & Review · 2020

Aim: A study was carried out to determine the in vitro antibacterial activity of ethanol extract of root and bark of Securidaca longipedunculata against two standard isolates of Neisseria gonorrhoeae NO.0296 and WHO- K. Materials and Methods: Plant materials were collected and dr...

Open access Research Article 10.9734/ijbcrr/2020/v29i630199

Serum Melatonin with Respect to Mental Health (Anxiety & Depression) Status of First Year M.B.B.S Students

Vinita H. Belsare, Arun Tadas, Sanjay Agrawal & Hrishikesh Belsare · International Journal of Biochemistry Research & Review · 2020

Introduction: Melatonin is a pineal hormone secreted in circadian manner, with a peak during evening and night. Night-time light exposure is a powerful suppressor of nocturnal melatonin secretion. Dopamine and serotonin have complex relationship in melatonin synthesis and secreti...

Open access Research Article 10.9734/ijbcrr/2020/v29i630198

Inhibitory Potential and Antidiabetic Activity of Leaf Extracts of Justicia carnea

Onuabuchi Nnenna Ani, Stanley Chidi Udedi, Kelechi Kingsley Asogwa, Michael Okey Enemali, Chigozie Michael Onwelumadu & Kenneth Segun Ikedife · International Journal of Biochemistry Research & Review · 2020

The aim of this study was to evaluate the in-vitro inhibitory potential of various leaf extracts of Justicia carnea on alpha-amylase and alpha-glucosidase activities and the anti-diabetic activity of the ethanol leaf extract using albino wistar rats. The analyses were carried out...

Open access Research Article 10.9734/ijbcrr/2020/v29i630194

Impact of Illegal Crude Oil Refining in Jike-ama River of Bille Kingdom, Rivers State, Nigeria

Nwachoko, Ndidi, Davies, Bekinbo & Tetam, Jack Gbenenee · International Journal of Biochemistry Research & Review · 2020

Oil exploration and exploitation is a lucrative business and one of the major sources of revenue in Nigeria. Each year, hundreds of post-impact assessment (PIA) studies are conducted to assess the impact of the hazards generated by the oil industry on social environment and on hu...

Open access Research Article 10.9734/ijbcrr/2020/v29i630195

Study of Staining Capability of Alcoholic and Aqueous Hibiscus sabdariffa Extract in Demonstration of Selected Fungal Moulds in Some Selected Tissue Section of Wistar Rat

S. Y. Ma’aruf, M. O. Mohammed, O. G. Avwioro, A. T. Muhammad, R. I. Tsamiya, U. Abubakar, I. Mohammed, A. Umar, S. M. Sani, H. Kabir, B. A. Bello, S. D. Abubakar, F. A. Dogondaji, N. Okorie & S. Garba · International Journal of Biochemistry Research & Review · 2020

Introduction: Hibiscus sabdariifa is a natural dye, generally called roselle. Most of Synthetic dye  have been established to cause toxicity. The aim of this research was to determine the staining effect of different concentration of Hibiscus sabdariffa extracts at various pH, du...

Open access Research Article 10.9734/ijbcrr/2020/v29i630193

Analyses of Homing Endonucleases and Mechanism of Action of CRISPR-Cas9 HNH Endonucleases

Peramachi Palanivelu · International Journal of Biochemistry Research & Review · 2020

Aim: To analyze different HNH endonucleases from various sources including the HNH endonuclease regions of CRISPR-Cas9 proteins for their conserved motifs, metal-binding sites and catalytic amino acids and propose a plausible mechanism of action for HNH endonucleases, using CRISP...

Open access Research Article 10.9734/ijbcrr/2020/v29i630192

Assessment of Antiplasmodial and Antioxidant Activities, Total Phenolics and Flavonoids Content, and Toxicological Profile of Cola millenii K. shum (Malvaceae)

Gerard Hodeve Tiko, Abdou Madjid O. Amoussa, Rafiou Adamou, Adande A. Medjigbodo, Luc S. Djogbenou & Latifou Lagnika · International Journal of Biochemistry Research & Review · 2020

Aims: This study was designed to assess antiplasmodial and antioxidant activities in relation to phytochemical contents and toxicological profile of crude extracts of Cola millenii leaves. Place and Duration of Study: The study was carried out from April 2015 to November 2018 at...

Open access Research Article 10.9734/ijbcrr/2020/v29i530191

Preliminary Antidiabetic Potential of Ugandan- Matooke (Musa paradisiaca) Peels

Adaku Vivien Iwueke, Nnamdi John Ejekwumadu, Roland Kiiza, Kenneth Iceland Kasozi & Swafia Khambari · International Journal of Biochemistry Research & Review · 2020

Background: Diabetes mellitus is a metabolic disease characterized by hyperglycaemia over a prolonged period. In Uganda, unripe Musa paradisiaca (banana) is a staple food which is deskinned before cooking. In West Africa, however, the unpeeled banana is cooked for diabetics. Aim:...

Open access Research Article 10.9734/ijbcrr/2020/v29i530190

Antimicrobial Efficacy of Methanolic and Aqueous Extracts of Partially Purified Protein from Young and Matured Root of Guiera senegalensis (Moshi Medicine)

M. K. Jiyil, M. I. Shago, C. E. Mafuyai, M. Silas & O. A. Olorunyomi · International Journal of Biochemistry Research & Review · 2020

Background: Antibiotic resistance among pathogenic bacteria is increasing at an alarming rate leading to the need for traditional medicine as an alternative. Aim of the Study: The study aimed to evaluate the antimicrobial activity of methanolic and, aqueous extracts of partial pu...

Open access Research Article 10.9734/ijbcrr/2020/v29i530189

Evaluation of Anti-oxidant Enzymes, Lipid Peroxidation, Lipid Profile and Liver Function in Albino Rats Orally Administered Tartrazine

Uyota Anthony Adele, Geraldine Iroh, Ojoye Ngoye Briggs, Helen Anthony Waribo & Ibioku Elekima · International Journal of Biochemistry Research & Review · 2020

Aim: To evaluate the anti-oxidant enzymes, lipid peroxidation, lipid profile and liver function in albino rats orally administered tartrazine. Study Design: A total number of 63 female albino rats weighing approximately 0.2 kg were used for this study. The study was divided into...

Open access Research Article 10.9734/ijbcrr/2020/v29i530188

Biochemical and Microbiological Evaluation of the Effect of Processing on Cucumeropsis mannii Seed

A. O. Ileola, T. R. Omodara & O. A. Awoyinka · International Journal of Biochemistry Research & Review · 2020

The determination of the effect of processing on nutritional composition and level of undigested oligosaccharide in Cucumeropsis mannii seeds was carried out. The dried melon seeds were sorted, cleaned, soaked in 60mL water for 15 min for easy removal and de-hulled to get the cot...

Open access Research Article 10.9734/ijbcrr/2020/v29i530187

In-vitro and In-vivo Antioxidant Activity of Ethanol Leaf Extract of Justicia carnea

Udedi Stanley Chidi, Ani Onuabuchi Nnenna, Asogwa Kingsley Kelechi, Maduji Fitzcharles Chijindu & Okafor Clinton Nebolisa · International Journal of Biochemistry Research & Review · 2020

This study investigated the in-vitro antioxidant activity of ethanol leaf extract of Justicia carnea and its effect on antioxidant status of alloxan-induced diabetic albino rats. The in-vitro antioxidant activity was assayed by determining the total phenol, flavonoids, ascorbic a...

Open access Research Article 10.9734/ijbcrr/2020/v29i430185

Optimization of the Process Parameters for Extraction of Millet Milk

K. Shunmugapriya, S. Kanchana, T. Uma Maheswari, R. Saravanakumar & C. Vanniarajan · International Journal of Biochemistry Research & Review · 2020

This study was undertaken to evaluate the effect of different processing methods on extraction of millet milk viz., germinated millet milk extraction, germinated and roasted millet milk extraction; enzyme assisted millet milk extraction and ultrasonicated millet milk extraction....

Open access Research Article 10.9734/ijbcrr/2020/v29i430184

Hibiscus sabdariffa Aqueous Leaf Extract Reverses Hematological Alterations in Phenylhydrazine Anemic Wistar Rats

E. B. Umoren, T. A. Kolawole, I. Wopara, O. G. Adebayo, B. Ben-Azu, J. I. Uzokwe & A. O. Obembe · International Journal of Biochemistry Research & Review · 2020

Background: The extract of Hibiscus sabdariffa commonly known as Sobo is widely consumed for its nutritional and health benefits. This study investigated the effect of aqueous leaf extract of  H. sabdariffa on anemic condition caused by phenylhydrazine in rats. Materials and Meth...

Open access Research Article 10.9734/ijbcrr/2020/v29i430183