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All published articles 1167

N-Acetylcysteine Inhibits Lipids Production in Mature Adipocytes through the Inhibition of Peroxisome Proliferator-Activated Receptor 

Daniela Soto, Claudia Martini, Evelyn Frontera, Laura Montaldo, Maria C. Vila, Juan C. Calvo & Liliana N. Guerra · International Journal of Biochemistry Research & Review · 2020

Aims: Reports regarding the effects of antioxidants in obesity have been contradictory. Antioxidant N-acetylcysteine is usually considered a nutritional supplement. Our aim is to evaluate bioactivity of N-acetylcysteine (NAC) on mature adipocytes, which is a close model to in viv...

Open access Research Article 10.9734/ijbcrr/2020/v29i430182

Effect of Methanol Extract of Unripe Carica papaya Pulp on Lipid Profile and Liver Function of Alloxan-Induced Diabetic Rats

Henry N. Ogbonna, Ugonna D. Nwankpa, Godwin S. Aloh & Raymond C. Ibeh · International Journal of Biochemistry Research & Review · 2020

Background: Carica papaya is commonly used in the treatment of various diseases like constipation, piles, hypertension and malaria. The ameliorative effect of Carica papaya on alloxan-induced diabetic rats has been suggested by several studies. Aim: The present study aims to inve...

Open access Research Article 10.9734/ijbcrr/2020/v29i430180

Estimation of Urinary Delta Aminolevulinic Acid (δ-ALA) Levels in Students of Age Group 15 to 25 Years as an Index of Lead Exposure

Sachin A. Patharkar, Suraj H. Jain, Alka V. Nerurkar, Neelam J. Patil & Pradeep N. Surve · International Journal of Biochemistry Research & Review · 2020

Background: Lead poisoning is a serious and sometimes fatal condition. It occurs when lead builds up in the body. Students exposed to lead by eating junk foods wrapped in newspaper, the licking of fingers for turning the photocopies, book pages, printout etc. and use of same fing...

Open access Research Article 10.9734/ijbcrr/2020/v29i430181

Molecular Docking in Drug Discovery: A Review on Anti-snake Venom Development

Adewunmi Rofiat Funmilola, Gidado Abubakar & Zanna Hassan · International Journal of Biochemistry Research & Review · 2020

Snakebite is a frequent accident faced by rural community's dwellers, and it has remained a neglected public health problem in many countries. Snake venom is a complex mixture of proteins, and they participate to envenomation through a diverse array of bioactivities, such as blee...

Open access Research Article 10.9734/ijbcrr/2020/v29i330179

Screening Out the Phytochemicals and Colour Values in White and Black Rice Lines and Its Interrelationship

T. Vasantha Theiventhiran, S. Amutha, J. Ramalingam, G. Hemalatha & T. Umamaheswari · International Journal of Biochemistry Research & Review · 2020

Problem: Kavuni is a traditional black rice variety of Tamil Nadu, India it rich in nutritional and therapeutic properties.  These traits it is not being cultivated widely, due to long duration, poor tillering and low yielding agronomic characters. Objectives: In the  study, twen...

Open access Research Article 10.9734/ijbcrr/2020/v29i330178

Physiological Basis of Nonmemory Cognition in Alzheimers Disease-An Overview

A. S. V. Prasad · International Journal of Biochemistry Research & Review · 2020

Alzheimer's (AD) disease is foremost of the neurodegenerative diseases affecting cognition. Though memory, out of all cognitive functions of the brain, received much attention, the nonmemory cognitive functions including the higher brain functions, are equally important. In fact...

Open access Research Article 10.9734/ijbcrr/2020/v29i330177

Antidiabetic Activity of Aqueous and Ethanolic Extracts of Stem Barks from Trichilia emetica (Meliaceae) in Alloxan-Induced Diabeticalbinos Rats

Djoupo Agnon Prisca, Dere Kwadjo Anicet Luc, Manhan Kahissié, Yapi Houphouet Felix & Tiahou Gnomblesson Georges · International Journal of Biochemistry Research & Review · 2020

Aims: This study was designed to evaluate the antidiabetic effects of aqueous and ethanolic extracts of Trichilia emetica (TE) stem bark in albinos rats. Methodology: 24 rats of comparable weight were divided into 2 lots, including a control lot of 3 rats and a test lot of 21 rat...

Open access Research Article 10.9734/ijbcrr/2020/v29i330176

Toxicological Study of Leaf Extracts of Loranthus micranthus Linn Using Albino Wistar Rats

Ani Onuabuchi Nnenna, Ani Okwudili & Okwuosa Chukwugozie Nwachukwu · International Journal of Biochemistry Research & Review · 2020

This study was aimed to investigate the effect of high sub-chronic doses of the aqueous and methanol leaf extracts of Loranthus micranthus on biochemical parameters of albino rats. Acute toxicity studies were performed according to standard methods. The animals were divided into...

Open access Research Article 10.9734/ijbcrr/2020/v29i330175

Relation of Iron, TIBC and Oxidative Stress with Glycosylated Haemoglobin in Diabetes Mellitus

Nida Afreen Qureshi, Kavita More & Sandeep Rai · International Journal of Biochemistry Research & Review · 2020

Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycaemia with disturbances of carbohydrate, fat and protein metabolism. Scientific evidences suggest that high iron storage may play a role in pathogenesis of type 2 diabetes. Excess iron accumulation induces o...

Open access Research Article 10.9734/ijbcrr/2020/v29i330173

Effect of Time Interval between Collection, Plasma Separation and Analysis and the Effect of Temperature on the Laboratory Results of Plasma Glucose Estimation

Ashish Agarwal, Poornima Ajay Manjrekar, Afzal Ahmad & Charu Yadav · International Journal of Biochemistry Research & Review · 2020

Introduction: In a clinical laboratory, consistency of test results cannot be solely achieved by controlling the accuracy in the analytical phase of glucose estimation alone. Considering the high chances of pre-analytical errors, due consideration has to be given for storage crit...

Open access Research Article 10.9734/ijbcrr/2020/v29i230172

Nutrient and Bioactive Components of Annona muricata and Fagara zanthoxyloide of South-Southern Nigeria

O. U. Ekere, C. C. Monago-Ighorodje & C. U. Ogunka-Nnoka · International Journal of Biochemistry Research & Review · 2020

This study was aimed at investigating the nutrient and bioactive components of Annona muricata and Fagara zanthxoyloide from south-southern Nigeria. The roots and leaves of these plants were collected from communities within this region and an analysis of the phytochemical, miner...

Open access Research Article 10.9734/ijbcrr/2020/v29i230171

Phytochemical and Phytomineral Status of Spigelia anthelmia Linn Leaves

O. L. Awotedu, P. O. Ogunbamowo, O. S. Ariwoola & E. P. Chukwudebe · International Journal of Biochemistry Research & Review · 2020

Aims: Spigelia anthelmia is a medicinal plant used in the treatment of diverse diseases and contain plant-based natural bio-active constituents. Study Design: Phytochemical and mineral analysis of Spigelia anthelmia leaves using standard analytical procedures. Place and Duration...

Open access Research Article 10.9734/ijbcrr/2020/v29i230170

Physiological Basis of Memory Dysfunction in Alzheimer’s Disease – An Overview

A. S. V. Prasad · International Journal of Biochemistry Research & Review · 2020

Alzheimer’s disease (AD) is a neuro-degenerative disease, causing gradual decline in memory function in the affected patients. The loss of memory makes their existence miserable. It is first noticed and reported by the patient’s care takers. The clinicians objectively assess the...

Open access Research Article 10.9734/ijbcrr/2020/v29i230168

Effect of the Garcinia kola Seed on Glycemia, Creatininemia and Aminotransferases in Adult Subjects

Moutawakilou Gomina, Tarik Salifou, Gilbert Djidonou & Stanislas Zinsou · International Journal of Biochemistry Research & Review · 2020

Background: The administration of extracts of Garcinia kola seed to experimental rats has a hypoglycemic and hepatoprotective effect. Objective: Assess the effect of daily consumption of Garcinia kola seed on glycemia, creatinine and serum aminotransferases among adult subjects....

Open access Research Article 10.9734/ijbcrr/2020/v29i230169

Assessment of Cardiovascular Disease Risk in Prediabetes

Ashish Agarwal, Anupama Hegde, Afzal Ahmad, Charu Yadav, Poornima A. Manjrekar & M. S. Rukmini · International Journal of Biochemistry Research & Review · 2020

Introduction: Prediabetes is associated with dysglycemia, endothelial dysfunction, obesity and inflammation, placing them at an increased risk of cardiovascular events. Aims: The present study aimed to investigate the risk of cardiovascular disease associated with prediabetes by...

Open access Research Article 10.9734/ijbcrr/2020/v29i230166