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All published articles 1167

Ethanolic Extract of Solanum melongena Linn Fruit Mitigated Monosodium Glutamate-Induced Oxidative Stress

Uchendu O. Mbah & Anthony Cemaluk C. Egbuonu · International Journal of Biochemistry Research & Review · 2017

Background/Aim: Monosodium glutamate (MSG), a flavour enhancing food additive generally regarded as safe by food regulatory bodies at low concentration can induce oxidative stress at high concentration. The heightened search for underutilized plant-sourced food necessitated this...

Open access Research Article 10.9734/IJBCRR/2017/35055

Different Approaches for Quantification of the Bioactive Metastable Thiosulfinates in Garlic Using a Validated High Performance Liquid Chromatography Method

Florence A. Opondo, Were L. L. Munyendo, Patrick M. Shem & Raphael O. Nyayieka · International Journal of Biochemistry Research & Review · 2017

Aims: In this study Allium sativum extracts were evaluated for antibacterial activity, High Performance Liquid Chromatography method was developed and validated for direct quantification of alliin and indirect quantification of metastable bioactive thiosulfinates. Study Design: T...

Open access Research Article 10.9734/IJBCRR/2017/35180

The Proximate Composition and Essential Oils of Processed Pentaclethra macrophylla Seeds

U. C. Nwosu, W. B. Abbey, E. B. Essien & R. C. Ohiri · International Journal of Biochemistry Research & Review · 2017

The chemical composition of various stages of processed Pentaclethra macrophylla (PM) seeds were investigated using standard analytical procedures. The PM seeds were processed in different stages, of raw (uncooked), 1st cooking (cooked for 16-18 hours and dehulled), 2nd cooking (...

Open access Research Article 10.9734/IJBCRR/2017/35235

Thyroid Status, Renal Profile and Electrolytes in Postmenopausal Women

Usha Sachidananda Adiga · International Journal of Biochemistry Research & Review · 2017

Introduction: Diminished gonadal hormones after menopause are found to influence thyroid status, renal functions as well as electrolyte balance. There are a few published data in this area, to the best of our knowledge. Aim of our study was to compare thyroid status, renal profil...

Open access Research Article 10.9734/IJBCRR/2017/35254

HPLC Profile of Bioactive Compounds Present in Olea europeae, Myrtus communis and Monotheca buxifolia and their Antibacterial Activities

Muhammad Zahoor, Naveed Ahmad, Huma . & Farzana . · International Journal of Biochemistry Research & Review · 2017

Aims: In this study the aqueous extract of Olea europeae, Myrtus communis and Monotheca buxifolia were screened for antibacterial activity, total phenolic content, polyphenol, chlorophyll a, chlorophyll b, β-carotene and lycopene. Design of the Study: The study is composed of ide...

Open access Research Article 10.9734/IJBCRR/2017/34556

Effect of Aqueous Extract of Sphenostylis stenocarpa on Some Liver and Kidney Parameters of Wistar Rat

Okoye Ngozi Franca & Esiobise Ufuoma Monica · International Journal of Biochemistry Research & Review · 2017

Aim: Aqueous extract of the seed of African Yam Bean (Sphenostylis stenocarpa) is used in Nigerian alternative medicine for the treatment of hypertension. The objective of this study is to investigate the effect of Sphenostylis stenocarpa seed extract on the liver and kidney func...

Open access Research Article 10.9734/IJBCRR/2017/34274

Sensory Properties and Microbial Characteristics of Cookies Prepared from Refined Wheat Flour Supplemented with Sweet Potato Flour and Whey Protein Concentrate

Blessy Sagar Seelam, John David, Neha Singh & Sonia Morya · International Journal of Biochemistry Research & Review · 2017

A study was conducted for sensory analysis and microbial assay for the cookies supplemented with refined wheat flour, sweet potato flour and whey proteins concentrate (WPC-80). The cookies made were nutritious products for all peoples. The product on the whole composed of sweet p...

Open access Research Article 10.9734/IJBCRR/2017/33992

Interleukin 10 Gene Polymorphisms and Susceptibility to Nephropathy in Egyptian Diabetic Patients

Mohammad Sayyed Bakheet · International Journal of Biochemistry Research & Review · 2017

Background: Type 2 diabetes mellitus (T2DM) is recognized as one of the most common causes of end-stage renal disease. In T2DM patients, a certain cytokine genotype is associated with an increased susceptibility to diabetic nephropathy. Aim: In this study we clarify the relation...

Open access Research Article 10.9734/IJBCRR/2017/34735

The Phosphocreatine-ATP Energy Shuttle and Muscle Action: Misconceptions, Oversights and Insights

Sosale Chandrasekhar · International Journal of Biochemistry Research & Review · 2017

The role of phosphocreatine (PC) as an ‘energy buffer’ in muscular contraction needs to be reassessed from several viewpoints. In particular, the view that the hydrolysis of PC is more exergonic than that of ATP is erroneous, as the enthalpy and Gibbs free energy changes (respect...

Open access Research Article 10.9734/IJBCRR/2017/34643

Resistin Inhibits the Synthesis of Insulin by miR-494 through Traget on CREB1

Fengyun Wen, Yi Yang, Hubin Fang, Leitong Nie, Lei Li, Yi Chen, Yu Liang, Qing Wang & Zaiqing Yang · International Journal of Biochemistry Research & Review · 2017

Resistin was first described as an adipokine and found to impair the pancreatic beta cells. The reason that it was named “resistin” is because it related with insulin resistance. Our previous study showed that miR-494 were significantly downregulated by resistin, while it is unkn...

Open access Research Article 10.9734/IJBCRR/2017/33384

25 (OH) Vitamin D level and Calcium/Phosphorus Metabolism Disorders in Patients Living with HIV in Abidjan

Lydie Boyvin, Jeanne Armande Aké, Kipré Laurent Séri, Gervais Melaine M’boh, Adou Francis Yapo & Joseph Allico Djaman · International Journal of Biochemistry Research & Review · 2017

Aims: The present study was to evaluate the serum calcium level, phosphorus and 25 (OH) vitamin D subjects during HIV infection; precisely in patients living with HIV (PLHIV). Study Design: Prospective and experimental study, involving a cohort of blood samples from HIV-negative...

Open access Research Article 10.9734/IJBCRR/2017/34351

Toxicity Assessment of Sub Lethal Doses of Chlorpyrifos on the Kidney and Liver Organs of Male Wistar Rats

O. O. Fayinminnu, S. O. Tijani & O. O. Fadina · International Journal of Biochemistry Research & Review · 2017

Chlorpyrifos, an organophosphate pesticide is an important neurotoxic and tissue damage agent. It is one of the most heavily used pesticides in domestic and agricultural applications globally. Repeated doses of chlorpyrifos have been able to cause significant disturbances on the...

Open access Research Article 10.9734/IJBCRR/2017/31349

Quantitation of TLR-2 mRNA Expression in Bovine Mastitis Caused by E. coli

R. Lakshmi & K. K. Jayavardhanan · International Journal of Biochemistry Research & Review · 2017

Aims: This study aim was to assay the expression of an important TLR2 gene in naturally infected cows with sub-clinical and clinical mastitis caused by E. coli. Methodology: cDNA from E. coli infected samples were obtained from hind quarters of three animals with sub-clinical mas...

Open access Research Article 10.9734/IJBCRR/2017/33367

Identification, Characterization and Purification of MSC_0265, a Potential Immunogenic Antigen Homologue of Mycoplasma mycoides subsp. mycoides in Mycoplasma capricolum subsp. capripneumoniae

M. Orwe, J. Kinyua, J. Ngaira, H. Wesonga & J. Naessens · International Journal of Biochemistry Research & Review · 2017

In silico identification and characterization of vaccine antigens has opened up new frontiers in the field of reverse vaccinology to mitigate the effects of livestock diseases by development of new subunit vaccines. This study aims to characterize, express and purify MSC_0265 for...

Open access Research Article 10.9734/IJBCRR/2017/34125