Aims: The aim of this study is to explore the expression pattern of LIGHT and FGF-BP at the different stages of liver injury including acute injury, fibrosis and cirrhosis. Study Design: Controlled experiment. Place and Duration of Study: Department of Biochemistry and Departmen...
Open access
Research Article10.9734/IJBCRR/2016/26029
Increase in prevalence of resistant microorganisms especially to synthetic drugs, has necessitated the need to search for new bioactive compounds having natural origin. Thus it was essential to determine the antibacterial activity of hexane, dichloromethane, ethyl acetate and met...
Open access
Research Article10.9734/IJBCRR/2016/25863
Aims: The present study demonstrated a comparative evaluation of RNA isolation from pigeonpea by using conventional or modified laboratory based methods as well as optimizing the existing well known protocol to extract a satisfactory amount of purified and reproducible RNA requir...
Open access
Research Article10.9734/IJBCRR/2016/25978
Background: Serum tumor markers are widely used clinically for monitoring response to therapy and detecting cancer recurrence. However, only a limited number of them have been effectively used for the early detection of cancer. Objective: To review serum tumor markers used clinic...
Open access
Research Article10.9734/IJBCRR/2016/24832
This research work was carried out to determine the concentration of Cu, Mn, Pb and Fe in maize flour milled by different types of milling plates in Samaru, Zaria, Nigeria. Three different types of milling plates with the trade names GUK (Gibraltar upgrade kit), Parpela and Premi...
Open access
Research Article10.9734/IJBCRR/2016/21681
Aims: This study is a preliminary step in investigating the anti-diabetic effect of the methanolic extract of the leaf of Axonopus compressus (P. Beauv) in alloxan-induced diabetic rats. Study Design/Methodology: Intraperitoneal (i.p.) injection of alloxan monohydrate at the dose...
Open access
Research Article10.9734/IJBCRR/2016/25425
Since the techniques employed in refining can alter the chemical composition of edible oils, the phytosterol and vitamins A and E composition of branded vegetable oils sold in Nigeria were determined. The result showed that sitosterol, campesterol, stigmasterol and 5-Avenasterol...
Open access
Research Article10.9734/IJBCRR/2016/22920
Aim: This research work set to investigate the effect of feeding a mixture of two functional foods with a view to ascertain their therapeutic effect against Trypanosoma brucei brucei in challenged rats. Experimental Design: Complete randomized clinical trial design was used in th...
Open access
Research Article10.9734/IJBCRR/2016/24356
Aims: The aim of this study is to investigate the carbonic anhydrase inhibitory potential of Cadaba farinosa leaf extract. Methodology: Cadaba farinosa leaves were extracted using soxhlet apparatus by n-Hexane, followed by Ethyl acetate and then Methanol. The extracts were tested...
Open access
Research Article10.9734/IJBCRR/2016/24604
Background: Diabetic nephropathy is the major micro-vascular complication of type 2 diabetes mellitus (T2DM) and is the main cause for end-stage kidney disease. In view of metabolic derangements of T2DM, we went further to investigate the role played by oxidized low density lipop...
Open access
Research Article10.9734/IJBCRR/2016/25286
Herbal medicine also known as botanical medicine refers to using plants seeds, flowers, roots for medicinal purpose. Nyctanthes arbor-tristis Linn is a large shrub or small tree, found throughout in India as well as chitrakoot region. It is commonly known as Harshingar, night ja...
Open access
Research Article10.9734/IJBCRR/2016/25118
Background: The process of inflammation induces hepatic synthesis of various acute phase proteins such as high sensitivity C-reactive protein (hs-CRP) which is believed to play a role in insulin resistance. Higher incidence of type-2 diabetes mellitus has been observed with high...
Open access
Research Article10.9734/IJBCRR/2016/25305
Many theories have been put forward to explain insulin resistance in DM2. The cause of insulin resistance still remained an enigma till date. Defect in insulin signaling pathway is one such possibility considered for insulin resistance in DM2. For insulin signal transduction to o...
Open access
Research Article10.9734/IJBCRR/2016/24489
Background: Methionine is a sulfur-containing amino acid that is synthesized via a branch point in the aspartate metabolic pathway. S-adenosyl methionine is subsequently synthesized from methionine, and plays a critical role in the transfer of methyl groups to various biomolecule...
Open access
Research Article10.9734/IJBCRR/2016/25074
Typhoid fever is still a major public health problem in developing countries, where it remains endemic. With a view to searching for new antityphoid substances, Curcuma longa rhizome extracts and fractions were assessed for their antisalmonellal and antioxidant activities. The an...
Open access
Research Article10.9734/IJBCRR/2016/25106