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All published articles 1167

Sildenafil Determination by Using UPLC in Different Italian Viagra Tablets

Nicola Giarretta, Maria C. Mezzacapo, Antonella M. A. Di Giuseppe, Nicola Landi, Martina Lippert & Antimo Di Maro · International Journal of Biochemistry Research & Review · 2014

Aims: The introduction of generics drugs has brought the need for more control of their quality and purity. In Italy from June 23, 2013 the Pfizer® has no longer the patent for the Viagra’s production and other industries produce equivalent products containing Sildenafil citrate....

Open access Research Article 10.9734/IJBCRR/2014/12821

Alterations in Calcium-Binding Properties of Sarcoplasmic Reticulum Membrane Proteins Following Cardiac Injury

Artashes G. Guevorgyan · International Journal of Biochemistry Research & Review · 2014

Aims: The objective of present work is to investigate metabolic alterations associated with heart failure, particularly one of its manifestations, a sustained hypocalcemia that causes hemodynamic changes contributed to subsequent myocardial injury. Comparative study was carried o...

Open access Research Article 10.9734/IJBCRR/2014/9708

Phytochemical and in vitro Antibacterial Evaluation of the Ethanolic Extract of the Stem Bark of Entada africana Guill. & Perr and Sarcocephalus latifolus

J. C. Ifemeje, C. Egbuna, S. C. Udedi & H. I. Iheukwumere · International Journal of Biochemistry Research & Review · 2014

Aims: The phytochemical composition and the in vitro antibacterial activity of the ethanolic extract of the stem bark of Entada africana Guill. & Perr. and Sarcocephalus latifolus, on Staphylococcus aureus, Salmonella typhi, Escherichia coli and Bacillus subtilis were investi...

Open access Research Article 10.9734/IJBCRR/2014/11554

Comparative Study of the Physicochemical Properties of Vegetable Oil from Irvigna gabonesis and Citrullus colocynthis Dried Seeds Samples

I. O. Igwenyi · International Journal of Biochemistry Research & Review · 2014

Aim: Extraction and analysis of the physicochemical properties of vegetable oil from Irvigna gabonesis and Citrullus colocynthis were carried out to predict possible applications. Study Design:  It was designed to extract oil from the seeds and investigate the properties to indic...

Open access Research Article 10.9734/IJBCRR/2014/5863

Alcohol Induced Lipid DYS-homeostasis in the Prefrontal Cortex of Diabetic Rats

Shallie Philemon Dauda, Adebukola Adenuga, Adejumo Esther Ngozi, Ihyar Alamun Clement, Shotunde Damilola Faith & Esegbue Peters · International Journal of Biochemistry Research & Review · 2014

Aim: To investigate the potential importance of the association between alcohol consumption, diabetes andlipid homeostasisin the prefrontal cortex. Study Design: Twenty-four adult rats were randomly divided into four groups of six rats each viz; Group 1- Control, given rat pellet...

Open access Research Article 10.9734/IJBCRR/2014/6380

Antioxidant Activity Phenolics Flavonoids and Proanthocyanidins Content of Senecio anteuphorbium

Fatima Azzahra Lahlou, Fouzia Hmimid, Mohammed Loutfi & Noureddine Bourhim · International Journal of Biochemistry Research & Review · 2014

Aims: The present study aimed to evaluate the antioxidant activity of methanolic and aqueous extracts of Senecio anteuphorbium and to determine total phenolics, flavonoids and proanthocyanidins content of this plant from Southern Anti-Atlas of Morocco. Moreover the effect of solv...

Open access Research Article 10.9734/IJBCRR/2014/8179

Comparative Effects of Antidiabetic Drug, Metformin and Deferoxamine, on Serum Lipids, Serum Ferritin and Endocrine Indicators of Diabetes Mellitus Complications in Sreptozotocin Diabetic Rats

P. O. Okonkwo & ZSC Okoye · International Journal of Biochemistry Research & Review · 2014

Aims: Increasing evidence has indicated that iron overload not only increases risks of insulin resistance and diabetes, but also causes cardiovascular diseases in non-diabetic and diabetic subjects. The present study compared the effects of metformin (met) and deferoxamine (DFX)...

Open access Research Article 10.9734/IJBCRR/2014/11811

GC-MS Analysis of Phytocompounds of Leaf and Stem of Marsilea quadrifolia (L.)

Karikalan Gopalakrishnan & Rajangam Udayakumar · International Journal of Biochemistry Research & Review · 2014

Objective: To investigate the phytochemical constituents of methanolic extracts of leaf and stem of Marsilea quadrifolia (Linn.). Methods: The methanolic leaf and stem extracts of M. quadrifolia were prepared by standard procedure and concentrated at 40ºC using hot air oven. The...

Open access Research Article 10.9734/IJBCRR/2014/11350

Assessment of Serum Iron, Manganese and Cu/Zn Ratio in the Course of falciparum Malaria among Ivorian Patients (Côte d’Ivoire)

Kolia K. Innocent, M’boh G. Melaine, Bagré Issa & Djaman A. Joseph · International Journal of Biochemistry Research & Review · 2014

Objectives: The question of interaction between endemic malaria infection and nutritional status of the host is always controversial and their relationship remains difficult to establish. Furthermore, the nutritional requirements of the host include some trace elements that are a...

Open access Research Article 10.9734/IJBCRR/2014/10256

Adenosine Triphosphatase Activities of Zea Mays and Vigna unguiculata Exposed to Different Crude Oil Fractions

O. Olubodun Stella & E. Eriyamremu George · International Journal of Biochemistry Research & Review · 2014

This study was carried out to investigate the activities of some adenosine triphosphatases (ATPases) in the radicle of maize and cowpea grown in soils contaminated with crude oil and its fractions. Total ATPase, Ca2+ ATPase, Na+/K+ ATPase and Mg2+ ATPase activities were evaluated...

Open access Research Article 10.9734/IJBCRR/2014/7118

Role of Serum Adiponectin, IL-6 and Hs CRP in Nonalcoholic Fatty Liver Egyptian Patients

Amal Ahmed Mohamed, Wafaa Gh. Shousha, Olfat Shaker, Mohamed El-Sayed Mahdy, Eman M. A. Ibrahim, Seham Mohmoud & Ahmed khairalla · International Journal of Biochemistry Research & Review · 2014

Scientific Background: Non alcoholic fatty liver (NAFLD) is accumulation of fat in the liver cells of peoples who drink little or no alcohol causing mild steatosis with mostly no signs, symptoms or complication but this may progress to steatohepatitis (NASH) and may liver cirrhos...

Open access Research Article 10.9734/IJBCRR/2014/10240

Effects of Dietary Supplementation of Turmeric (Curcuma longa) and Black Cumin Seed (Nigella sativa) in Streptozotocin Induced Diabetic Rats

S. M. El-Bahr & A. A. Al-Azraqi · International Journal of Biochemistry Research & Review · 2014

Aim: The objective of the present study was to investigate the antidiabetic effects of Turmeric (Curcuma longa) and Black cumin seed (Nigella sativa) either alone or in combination on blood glucose concentration, body weight, water and food intake and selected biochemical paramet...

Open access Research Article 10.9734/IJBCRR/2014/11120

Anti-venom Activity of Mucuna pruriens Leaves Extract Against Cobra Snake (Naja hannah) Venom

Okere O. Shekins, Gabriel O. Anyanwu, Philip M. Nmadu & Olufunsho D. Olowoniyi · International Journal of Biochemistry Research & Review · 2014

Aim: The study was done to investigate the anti-venom activity of Mucuna pruriens leaves extract against cobra snake (Naja hannah) venom. Study Design: The mice were randomly grouped into six groups (A, B, C, D, E, and F) of five rats each. Group A served as the normal control (n...

Open access Research Article 10.9734/IJBCRR/2014/10394

Comparative Analysis of Cardio Metabolic Risk Factors in Context of Insulin Resistance among South Indian Obese and Non-obese Adolescents

Mahendra Bhauraoji Gandhe, Bhupendra Marotrao Gathe & Swapnali Mahendra Gandhe · International Journal of Biochemistry Research & Review · 2014

Background: Presently, it is of an utmost importance to know the prevalence of cardio metabolic risk factors and insulin resistance among obese adolescents in south Indian population, where genetic predisposition to obesity is high. This knowledge would enable us to take preventi...

Open access Research Article 10.9734/IJBCRR/2014/10131

Maternal Obesity and Malnutrition in Rats Differentially Affect Glucose Sensing in the Muscles and Adipose Tissues in the Offspring

Maher A. Kamel, Madiha H. Helmy, Mervat Y. Hanafi, Shimaa A. Mahmoud, Hanan Abo Elfetooh & Mahmoud S. Badr · International Journal of Biochemistry Research & Review · 2014

Background: The altered maternal/fetal metabolism appears to be associated with a diabetogenic effect in the adult offspring even in the absence of genetic predisposition. Aim: The study aimed to investigate the effect of maternal obesity and malnutrition on the peripheral glucos...

Open access Research Article 10.9734/IJBCRR/2014/10649