Structural changes in the gonads and liver of Oreochromis niloticus fed sub-lethal concentration of crude extract of Azadirachta indica leaf was investigated. The sub-lethal concentrations were earlier reported to inhibit reproduction in the fish species. Oreochromis niloticus of...
Open access
Research Article10.9734/IJBCRR/2014/7140
Aims: This study aimed to evaluate the degree of oxidative stress in gestational diabetes mellitus when compared to non-diabetic pregnant women. Methodology: This cross-sectional study included 73 participants (29 gestational diabetic women and 44 control pregnant women) attendin...
Open access
Research Article10.9734/IJBCRR/2014/10138
Aims: In this review, we bring further evidence in support of the hypothesis on the so-called respiratory and pH imbalance (RpHI) as a cause of long standing hypoxia within the whole organism, characteristic to the preneoplastic stage. Background: Carcinogenesis is a process by...
Open access
Research Article10.9734/IJBCRR/2014/8617
Aims: Proteins are targets for photodegradation due to absorption of incident light by endogenous chromophores, e.g aromatic side chains. In this work we study the role of Trp-disulfide triads in the light induced loss of immunoglobulin activity. Study Design: We investigated a s...
Open access
Research Article10.9734/IJBCRR/2014/8453
Aim: The aim of this study was to determine the effect of plant spices (Thymus vulgaris, Murraya koenigii, Ocimum gratissimum and Piper guineense) on hemoglobin glycation (HbA1c), lactate dehydrogenase (LDH), glucose-6-phosphate dehydrogenase (G6PD) and red blood cell (RBC) indic...
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Research Article10.9734/IJBCRR/2014/7202
Examination of endocrine disruption in tilapia fish (Oreochromis spp.) after exposure to sub-lethal concentrations of endosulfan, lindane, diazinon and malathion was evaluated by the quantification of 17-β-estradiol, progesterone and testosterone in fish. Female tilapia (96-110 g...
Open access
Research Article10.9734/IJBCRR/2014/9006
Background: Alcohol consumption accelerates the progression and worsens the outcomes of hepatitis C viral (HCV) infection in heavy and moderate drinkers. Our aim was to investigate the effects of two modes of oral ethanol feeding on induction of oxidative stress, impaired methyl...
Open access
Research Article10.9734/IJBCRR/2014/9689
Background: An estimated 2 million children die of malaria yearly, primarily because of Plasmodium falciparum and its complications. Plasmodium falciparum infection could lead to imbalance in micronutrient levels. Micronutrients such as zinc and copper are essential for immune fu...
Open access
Research Article10.9734/IJBCRR/2014/7827
Aims: This study was carried out to investigate the ulcero–protective activity of methanolic extract of Acacia ataxacantha leaves (MEAAL) against indomethacin and stress induced gastric ulcer in experimental rats. Study Design: Administration of MEAAL at the dose of 100mg/kg body...
Open access
Research Article10.9734/IJBCRR/2014/8747
Aim: Comparing cord blood levels of total Creatine kinase (CK) and Creatine kinase MB isoenzyme (CK-MB) in newborns delivered by vaginal delivery and cesarean section. Study Design: Descriptive prospective study. Place and Duration of Study: All neonates delivered from Septemb...
Open access
Research Article10.9734/IJBCRR/2014/8394
Aims: To characterize the serum complement innate immune system in three species of crocodilians native to southeast Mexico. Methodology: Plasma collected from three wild crocodilian species native to southeast Mexico were exposed to sheep red blood cells (SRBCs) to measure hemol...
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Research Article10.9734/IJBCRR/2014/7825
Aims: Extracellular heat shock protein 70 (Hsp70) is an adjuvant molecule that stimulates the immune system. The C-terminal domain of Hsp70 (C70), without the ATPase domain, is sufficient for antigen cross-presentation. However, the mechanism by which the receptor mediates the u...
Open access
Research Article10.9734/IJBCRR/2014/8699
Aims: Despite of intensive investigation of alcoholism consequences for nervous system, the full complex of such metabolic alterations in brain remains unknown. The aim of present work was to study the influence of chronic ethanol consumption on rats’ brain contents of free amino...
Open access
Research Article10.9734/IJBCRR/2014/8809
Periwinkles (Tympanotonus fuscatus) handpicked from the New Calabar River were acclimated to laboratory conditions in the research laboratory of the Chemistry Department of the Ignatius Ajuru University of Education, Rumuolumeni, Port Harcourt. They were subjected to concentratio...
Open access
Research Article10.9734/IJBCRR/2014/8079
Objectives: The aim of the present study was to assess Apolipoprotein B (Apo-B) and Triglyceride/High Density Lipoprotein Cholesterol (TG/HDL-C) ratio as indicators of insulin resistance (IR) with Homeostasis Model of assessment of insulin resistance (HOMA IR)) in metabolic syn...
Open access
Research Article10.9734/IJBCRR/2014/7590