Phenylalanine hydroxylase deficiency, historically described as phenylketonuria, occupies an unusual position in medicine. It was the first inherited metabolic disorder for which dietary intervention prevented intellectual disability, the first to be detected through population n...
Open access
Research Article10.9734/jammr/2026/v38i106221
Background: Rational use of broad-spectrum antimicrobials and appropriate post-discharge de-escalation are important components of antimicrobial stewardship. Objectives: The study aims to evaluate the clinical use of Cefoperazone/Sulbactam in hospitalised patients with infectious...
Open access
Research Article10.9734/jammr/2026/v38i106219
Harmony Uchenna Ibezim, Imesidayo Omua Eboreime-Oikeh, Chukwudalu Emmanuel Orji, Osarumwense Precious Otote, Gabriel Pelumi Ikusika & Helen Kwipnchep Njoya·Journal of Advances in Medicine and Medical Research·2026
Background: Metabolic syndrome is a major public health concern because the clustering of cardiometabolic risk factors, particularly hypertension and impaired glucose metabolism, substantially increases the risk of cardiovascular disease and type 2 diabetes. Aim: This study evalu...
Open access
Research Article10.9734/jammr/2026/v38i106220
Background: Nasolabial-fold correction can be achieved with hyaluronic acid (HA) fillers or autologous platelet-rich fibrin-based materials, but post-treatment tissue thickness may reflect different structural effects. Aims: To determine whether repeated autologous albumin platel...
Open access
Research Article10.9734/jammr/2026/v38i106215
Aims: This study assessed the diagnostic agreement between manual liquid-based cervical cytology (MLBC) and histopathology among HIV-positive women attending Machakos Level 5 Hospital, Kenya. Study Design: A prospective comparative cross-sectional study. Place and Duration of Stu...
Open access
Research Article10.9734/jammr/2026/v38i106217
Blessing Gerald Ibokette, Uyoyou Winners Efi, Efe Joseph Oni, Mohammed Eltaif Ali Mohammed, Luis Fernando Jimenez Cepeda, Sorrentina Awala, Ome Valentina Akpughe, Ediomo Ekabua, Sami Ahmed Ishag Salih, Claudiane Mouafo Madzoom, Onaolapo Oluwatayo, Huma Irfan, Abobaker Mohammed, Chijioke Okonkwo & Esan Folashade Janet·Journal of Advances in Medicine and Medical Research·2026
Cannabis and cannabinoid-based products are increasingly used by people with cancer, yet the term “cancer treatment” encompasses two fundamentally different questions: whether cannabinoids can relieve cancer- or treatment-related symptoms, and whether they can modify tumour biolo...
Open access
Research Article10.9734/jammr/2026/v38i106212
Background: Prostate cancer is the most common malignancy among Nigerian men, with the majority presenting late with high-grade disease. Objectives: This study aimed to evaluate the utility of p53 and Ki-67 biomarkers in Nigerian men with prostate cancer by determining their expr...
Open access
Research Article10.9734/jammr/2026/v38i106213
Background: Ultra-processed foods constitute a substantial proportion of dietary intake among U.S. adults and have been associated with several chronic diseases. Evidence regarding their relationship with colorectal cancer remains limited and inconsistent, particularly in nationa...
Open access
Research Article10.9734/jammr/2026/v38i106214
Background: Urinary tract infections (UTIs) contribute substantially to infectious disease morbidity, while locally derived antimicrobial resistance data remain limited in many semi-urban Nigerian settings. This study assessed uropathogen prevalence and antimicrobial susceptibili...
Open access
Research Article10.9734/jammr/2026/v38i106210
Background: Children with sickle cell anaemia (SCA) are at increased risk of invasive pneumococcal disease, making pneumococcal vaccination an important preventive measure. However, vaccine hesitancy may reduce uptake, particularly in resource-limited settings where access to vac...
Open access
Research Article10.9734/jammr/2026/v38i106211
Irene Gomes Ferreira De Oliveira, Karen Caroline Sousa Santos, Francilene Silva Santos, Ana Beatriz Acioli Faria, Bianca Abreu Pantoja, Carlos Eduardo Santos De Sousa, Denise Sena Maués, Felipe Valino Dos Santos, Fernanda Menezes Correa, João Antônio Carvalho Corrêa, Caio Vieira Pires, Leonardo Magalhães Santos, Maylane Cristina BARROS Sousa, Maytê Figueira Coimbra, Naiá Estrela Pinheiro, Nicholas Russo Amanajás, Richelly Cristine Queiroz Martins, Verena Salim Ramos De Almeida, Walter Lopes Neto, Wiliane Freire Pinheiro & Camila Carvalho do Vale·Journal of Advances in Medicine and Medical Research·2026
Objective: To synthesise current evidence on the recognition of signs and symptoms of pre-eclampsia and to examine how this recognition supports safe nursing care in primary health care. Methods: A narrative review with a structured literature search was undertaken. PubMed/MEDLIN...
Open access
Research Article10.9734/jammr/2026/v38i106209
Background: Blood storage is associated with progressive biochemical and cellular changes that may alter the concentrations of soluble adhesion molecules. Vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin (SELP) are important m...
Open access
Research Article10.9734/jammr/2026/v38i106208
Background: Artificial intelligence (AI) and machine learning (ML) are increasingly used to support earlier diagnosis, risk stratification, clinical decision-making, and personalised care. However, an operational gap persists between algorithmic performance and safe bedside imple...
Open access
Research Article10.9734/jammr/2026/v38i96207
High-risk human papillomavirus (hrHPV) DNA testing has transformed cervical cancer screening because it detects infection with substantially greater sensitivity than morphology-based approaches. Its principal limitation is biological: most hrHPV infections do not progress to canc...
Open access
Research Article10.9734/jammr/2026/v38i96205
Background: Artificial intelligence (AI)-based decision-support systems are increasingly used in perioperative care to support risk assessment, resource allocation, and surgical planning. However, these systems may not capture qualitative clinical information or “soft data” recog...
Open access
Research Article10.9734/jammr/2026/v38i96206