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All published articles 6159

The Potential of Differentiation-Related Gene-1 (DRG1) as a Biomarker for Metastasis of Estrogen Receptor-Positive Breast Cancer

Hillary Bor, Esther N. Maina, Benson Nyambega, Kirtika Tushar Patel, Charles Ochieng’ Olwal, Walter Nalyanya & Yahaya Gavamukulya · Journal of Advances in Medicine and Medical Research · 2021

Introduction: Breast cancer is major burden worldwide and the majority of breast cancers express estrogen receptors (ER) suggesting a high dependence on estrogen hormone. Age is among the major determinants of breast cancer development, however, although Western Kenya is one of t...

Open access Research Article 10.9734/jammr/2021/v33i2031118

Diabetes Mellitus as a Risk Factor for Drug Resistance Tuberculosis: A Retrospective Cohort Study at King Abdul Aziz University, Jeddah

Sumyia Mehrin M. D. Abulkalam, Mai Kadi, Mahmoud A. Gaddoury & Wallaa Khalid Albishi · Journal of Advances in Medicine and Medical Research · 2021

Background: The association between tuberculosis (TB) and diabetes mellitus (DM) is re-emerging with the epidemic of type II diabetes. Both TB and DM were of the top 10 causes of death.[1] This study explores diabetes mellitus as a risk factor for developing the different antitub...

Open access Research Article 10.9734/jammr/2021/v33i2031115

Comparison between Laparoscopic and Open Repair of Umbilical and Paraumbilical Hernia: A Randomized Controlled Trial Study

Arti Mitra, Unmed Chandak, Shiv Kumar Sahu, Yuvraj Pawaskar & Akanksha Waldia · Journal of Advances in Medicine and Medical Research · 2021

Background: Laparoscopic repair of umbilical and paraumbilical hernia has largely replaced conventional (Open) repair. The purpose of the study was to compare the effectiveness of laparoscopic vs. open repair of umbilical & para umbilical hernia in a tertiary care government...

Open access Research Article 10.9734/jammr/2021/v33i2031114

The Relation between Iron and Vitamin B12 Status with Coronary Artery Disease

Kholoud M. Shamallakh, Ohood M. Shamallakh, Heba M. Arafat & Mazen M. Alzaharna · Journal of Advances in Medicine and Medical Research · 2021

Aims: To investigate the association of iron and vitamin B12 status with coronary artery disease in Gaza city. Study Design: A Case control study Place and Duration of Study: Samples were collected from the cardiac unit at Al-Shifa hospital, Gaza Strip. Methodology: Case-control...

Open access Research Article 10.9734/jammr/2021/v33i2031112

Early Uterine and Umbilical Artery Doppler Indices as Predictor for Preeclampsia and Intrauterine Growth Restriction

Sara E. Khalil, Mohammed M. Elnamory, Mona K. Omar & Hesham M. Eltokhy · Journal of Advances in Medicine and Medical Research · 2021

Background: Preeclampsia (PE) is a disorder that causes hypertension and proteinuria after week 20 of pregnancy. Several Uterine Artery (UtAs) Doppler characteristics have been investigated for their ability to predict PE. The purpose of this research is to look into the uterine...

Open access Research Article 10.9734/jammr/2021/v33i2031113

Mean Sac Diameter Minus Crown Rump Length as a Predector of Early Pregnancy Outcome

Hasnaa M. Mosbah, Mona K. Omar, Manal F. Hemisa & Elsayed F. Rakha · Journal of Advances in Medicine and Medical Research · 2021

Background: Mean sac diameter (MSD) is a sonographic measurement of the gestational sac which is usually first seen at around 5 weeks, when it measures about 2-3 mm, It's the average of measurements taken in three dimensions.Crown rump length (CRL) defined as the length of the em...

Open access Research Article 10.9734/jammr/2021/v33i2031110

Recent Advances in Drugs and Vaccines for COVID-19

Meiqin Tang, Xinhuang Yao, Faqing Tian, Man Jiang & Jianshe Yang · Journal of Advances in Medicine and Medical Research · 2021

Several potential COVID-19 therapeutic approaches and SARS-CoV-2 vaccines have been investigated, and final clinical reports are gradually becoming available. In this mini-review, we discussed the history of selected potential therapeutic drugs and newly designed vaccines, as wel...

Open access Research Article 10.9734/jammr/2021/v33i2031106

Elevated Plasma Fibrinogen and the Risk of Stroke: A Hospital Based Prospective Case-Control Study in Uyo, Nigeria

Timothy A. Ekwere, Olufisayo G. Ayoade, Bertha C. Ekeh & Franklin O. Dike · Journal of Advances in Medicine and Medical Research · 2021

Background: Stroke is one of the leading causes of morbidity and mortality globally. In recent time, there is increasing evidence that suggest that increased plasma fibrinogen is associated with increased risk of stroke with unfavourable clinical outcome. Objectives: To determine...

Open access Research Article 10.9734/jammr/2021/v33i2031104

Evaluation of Serum Presepsin in the Diagnosis and the Prognosis of Cirrhotic Patients with Ascites

Aziza Mohamed Hamed Zian, Mervat Abd El-Hameed Elkhateeb, Amira Youssef Ahmed & AL Zahraa Abd El-Azeam Allam · Journal of Advances in Medicine and Medical Research · 2021

Background: Liver cirrhosis is a serious problem associated with spontaneous bacterial peritonitis and renal dysfunction. Presepsin is a soluble Cluster of Differentiation 14 (CD14) Protein subtype that has been implicated as an important biomarker in many diseases. Objective: To...

Open access Research Article 10.9734/jammr/2021/v33i2031105

Association of Cervical Intraepithelial Lesions in Women with Genital Warts; A Cytological and Molecular Study

Nada S. Fathallah, Ahmed M. Hagras, Safinaz H. El-Shorbagy & Manal M. Abd Allah · Journal of Advances in Medicine and Medical Research · 2021

Background: Cervical cancer is a major health concern worldwide, according to the World Health Organization. It is now the fourth most common cancer after breast, colorectal and lung cancers in women worldwide. It is also the world's third most common cause of cancer death in wom...

Open access Research Article 10.9734/jammr/2021/v33i2031107

High Normal Thyrotropin (TSH) is Associated with Higher Needed Dose of Erythropoietin in Hemodialysis Patients

Ibrahim Ali Abd Elsalam Rady, Mervat Abd Elhamid Elkhateeb, Maaly Mohamed Mabrouk & Noha Elsayed Esheba · Journal of Advances in Medicine and Medical Research · 2021

Background: Recombinant human erythropoietin demonstrated an impressive ability to improve hematocrit, raising hematocrit of hemodialysis patients, eliminating the need for transfusions, and in patients with iron overload, decreased serum ferritin. Thyrotropin could affect hemato...

Open access Research Article 10.9734/jammr/2021/v33i2031103

Knowledge, Attitude, and Perception of COVID-19 Pandemic in Enugu, Southeast Nigeria- The Initial Experience

E. K. Mgbe, C. G. Mgbe, S. N. Ezeofor & J. F. Etiki · Journal of Advances in Medicine and Medical Research · 2021

Background: The world is experiencing a global corona virus (COVID-19) pandemic. As of 9th June 2020, over 7 million confirmed cases of coronavirus disease (COVID-19) and more than 400,000 deaths had been reported in more than 30 countries of the world according to World Health O...

Open access Research Article 10.9734/jammr/2021/v33i2031101

Role of Serum Cystatin C in Early Diagnosis of Acute Kidney Injury in Neonates with Bronchopulmonary Dysplasia

Sara Mohamed Elashry, Maher Ahmed Abdelhafez, Mostafa Mohamed Awny, Nahed Mohamed Elwan & Hamed Mohamed Elsharkawy · Journal of Advances in Medicine and Medical Research · 2021

Background: The neonate is more susceptible to acute kidney injury (AKI) than others due to functional and developmental immaturity, hemodynamic changes that occur at birth, and possibility of hypovolemia due to increased insensible water losses. The aim of this work was early de...

Open access Research Article 10.9734/jammr/2021/v33i2031102

Insulin-Like Growth Factor Binding Protein-2 in Systemic Lupus Erythematosus Patients as a Marker of Lupus Nephritis Disease

Zeinab N. ELRefeai ELgody, Ghadah Mahmoud Alghzaly, Mohammed Attia Saad Attia & Mohammed Mohammed Albedawey · Journal of Advances in Medicine and Medical Research · 2021

Background: One of the members of Insulin-like Growth Factor Binding Protein family is IGFBP-2 that binds to the Insulin-like Growth Factor (IGF) receptors to regulate IGF biological activities. In nephrotic syndrome IGFBP-2 has also been reported to be increased in children and...

Open access Research Article 10.9734/jammr/2021/v33i2031099

Multidetector Computed Tomography in Diagnosis of Mesenteric Vascular ‎Occlusion

Amira Mohammed Salah Abou Dalal, Rania Sobhy Abou Khadrah, Aymen Abdul Hameid Elnemr & Mohammed Fathy Dawoud · Journal of Advances in Medicine and Medical Research · 2021

Background: Multidetector computed tomography (MDCT) has high sensitivity and ‎specificity for diagnosing acute primary mesenteric ischemia (MI). MDCT findings vary ‎widely depending on the cause and underlying pathophysiology. MDCT findings of ‎mesenteric ischemia should be char...

Open access Research Article 10.9734/jammr/2021/v33i2031100