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All published articles 6159

In-silico Investigation and Potential Therapeutic Approaches of Acanthus montanus for COVID-19: Computer-aided Drug Design Perspective

Omobolaji Odunowo · Journal of Advances in Medicine and Medical Research · 2025

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in a significant number of fatalities globally, establishing it as a critical and urgent public health concern.  Phytochemicals may serve as a valuable source of effective and safer therapeutic agents a...

Open access Research Article 10.9734/jammr/2025/v37i45806

Impact of Prolonged Emergency Department Stays Due to ICU Bed Shortage on Patient Outcomes

Erkan Boğa · Journal of Advances in Medicine and Medical Research · 2025

Background: The rising demand for intensive care unit (ICU) beds has led to frequent delays in ICU admissions, extending patient stays in emergency departments (EDs) and potentially worsening outcomes. Understanding the clinical impact of these delays is vital for healthcare impr...

Open access Research Article 10.9734/jammr/2025/v37i45807

Efficacy of Proton Pump Inhibitors vs. H2 Receptor Antagonists in Managing GERD: A Systematic Review and Meta-Analysis

Ghazala S. Virk, Sarah Hack, Hemamalini Anand Murugesan, Pendyala Seetharam, Mahnoor Shah, Sana Afzal, Muhammad Hassan Saleem, Izzat Izzat, Masood Ahmed & Muhammad Sohail S. Mirza · Journal of Advances in Medicine and Medical Research · 2025

This systematic review and meta-analysis aimed to compare proton pump inhibitors (PPIs) and H2 receptor antagonists (H2RAs) in treating gastroesophageal reflux disease (GERD), with a focus on symptom resolution and esophagus lining recovery. Out of a total of 10 studies on sympto...

Open access Research Article 10.9734/jammr/2025/v37i45805

A Review on Block Chain Technology in Healthcare: Assessing Its Impact on Pharmacovigilance and Drug Tracking

Pranitha Avunoori, Aishwarya, K. Nandhini, Laxmi Prasanna & G. Mounika · Journal of Advances in Medicine and Medical Research · 2025

Blockchain technology is changing the face of several industries, but in health care, it is proving to be a critical tool to improve prescription drug tracking and pharmacovigilance. Prescription drug counterfeiting and safety monitoring pose significant global challenges that re...

Open access Research Article 10.9734/jammr/2025/v37i45804

Advances and Challenges in the Treatment and Control of Myeloid Smallpox

Kalebe Filipe Biasi da Costa, Wallace William da Costa & Helierson Gomes · Journal of Advances in Medicine and Medical Research · 2025

Mpox is a rare viral disease and continues to be a threat today. Recently, an increase in cases has been seen in African and other countries. This study aims to analyze the available evidence on advancements in Mpox treatment and the identified challenges. Methodology: A systemat...

Open access Research Article 10.9734/jammr/2025/v37i45803

Helicobacter pylori: Strategies to Mitigate Antimicrobial Resistance

Cinnamon Akuoma Okwandu, Mary-Anne Osayomore Amayaevbo, Naomi Ifeoma Oyiana, Donald Jaiyeola, Prince Akachukwu Nwajuaku, Munachimso Beatrice Emele, Prosper Ikenna Elenwoke & Olugbenga Morebise · Journal of Advances in Medicine and Medical Research · 2025

Introduction: Helicobacter pylori, a gram-negative, spiral-shaped bacterium, is involved in the pathogenesis of several gastrointestinal disorders, ranging from mild gastric ulcers to severe conditions such as chronic gastritis, MALT lymphoma, and gastric cancer. This review exam...

Open access Research Article 10.9734/jammr/2025/v37i45801

Clinical, Phenotypical and Epidemiological Analysis of Asthma in the West of Santa Catarina, Brazil

Thays Sarovisky Baiel, Carina Vittorello, Leda Sandrin, Guilherme Wilson Meirelles Tenfen, Jeana Cristina Barretta & Junir Antônio Lutinski · Journal of Advances in Medicine and Medical Research · 2025

Background: Asthma is a chronic inflammatory disease that predisposes to dyspnea, chest tightness, wheezing, and coughing. Geographical variations, pollution, allergen exposure, smoking and climate change interfere with the morbidity and mortality of the disease.  Objective: Anal...

Open access Research Article 10.9734/jammr/2025/v37i45802

Optimizing Emergency Management of Gunshot Trauma: Advanced Strategies in Accident and Emergency

Daniel Temiloluwa Oyedemi, Chigozie Doris Opara, Edibokun Theresa Orobator, Olabisi Promise Lawal, Ijeoma Linda Okwuowulu, Tolulope Catherine Ajayi & Oladimeji Samson Onifade · Journal of Advances in Medicine and Medical Research · 2025

Gunshot trauma is an increasing global public health concern, resulting in significant morbidity and mortality.  In this review, we evaluated the most recent literature on best practices for emergency gunshot trauma care, emphasizing novel techniques to improve patient outcomes. ...

Open access Research Article 10.9734/jammr/2025/v37i45799

How Can We Achieve Maximum Maxilla Expansion Using the Maxillary Multi-segmentation Technique in Orthognathic Surgery?

Igor Thiago Bragatto de Mendonça, Andréa Juliana Luz Perdigão, Marilia de Oliveira Coelho Dutra Leal, Renato Assis Machado, Roberto Macoto Suguimoto, Rubens Gonçalves Teixeira & Claudio Roberto Pacheco Jodas · Journal of Advances in Medicine and Medical Research · 2025

Aims: To describe maxillary multi-segmentation technique (MMST) during orthognathic surgery illustrated through a clinical case. Study Design: Original Research Article. Methodology: Maxillary transverse deficiency is a complex etiological condition that can impact individuals of...

Open access Research Article 10.9734/jammr/2025/v37i45797

Relationship between Mortality and Severity of COVID in Patients with Diabetes Mellitus: A Systemic Review

Osman Suliman, Riham Abd Elmagid & Rana Abd Elmagid · Journal of Advances in Medicine and Medical Research · 2025

This systematic review analyzes the association between mortality and the severity of COVID-19 in patients with diabetes mellitus is a significant concern that requires further investigation. Diabetes mellitus has been identified as a major risk factor for severe illness and incr...

Open access Research Article 10.9734/jammr/2025/v37i45798

Digital Microvascular Occlusion in Essential Thrombocythemia: A Case Report and Review of Management Strategies

Amiwero E. Christian, Aderinto Oyindamola, Odunafolabi Tunde, Oyeniran Oluwaseye, Babalola Tope Idowu & Odetunde Odetunde Israel · Journal of Advances in Medicine and Medical Research · 2025

Aim: This case report aims to address the apparent lack of documented instances of digital microvascular occlusion secondary to essential thrombocythemia (ET) in the southwestern region of Nigeria, while also providing a review of management strategies. Presentation of Case: This...

Open access Research Article 10.9734/jammr/2025/v37i45796

Analysis of Male Population Knowledge about the Men's Health Program in the Municipality of Belém-PA

Bárbara Castro Sena Monteiro, Andreza Santos dos Reis, Esteffane Abigail de Souza Costa, Camila Carvalho do Vale, Amanda Jordana Silva Souza, Bernar Antônio Macedo Alves, Brendo Silva Gaia Farias, Caio Lacerda dos Santos, Diogo Farias Costa, Eduarda Sarte Magnago, Gabriel Miranda Bacelar, Gabriel Ribeiro de Souza, Girlane Alves Pinheiro, Glenda Keyla China Quemel, Isabelle Soria Galvarro Franco, Jessica Ismênia de Lucena Lima, Jhessica Harlen Sanches Bittencourt, Kathleen Higham Giestas, Luís Arthur Moreira Ferreira, Luisa De Déa Januário, Maylane Cristina BARROS Sousa, Paulo Victor Guterres Ribeiro, Rafael Malcher Meira Rocha, Suzan Karoline Garcia Ferreira, Thiago Vilhena Silva & Yuri do Carmo da Silva · Journal of Advances in Medicine and Medical Research · 2025

Objective: To investigate the level of knowledge among the male population regarding the Men's Health Program in the municipality of Belém-PA. Methods: This is a cross-sectional study with a quantitative approach, conducted with 174 male individuals aged 20 to 59 years. Participa...

Open access Research Article 10.9734/jammr/2025/v37i45795

Detection of KPC-producing Enterobacteria and Antimicrobial Resistance in Brazilian Sewage Treatment Plants

Jaime Antonio Abrantes, Líllian Oliveira Pereira da Silva, Emanuele Amorim Alves & Joseli Maria da Rocha Nogueira · Journal of Advances in Medicine and Medical Research · 2025

Background and Aims: Pathogenic microorganisms can be found in sewage and may cause several infections and deleterious health effects. In this scenario, Enterobacterales can trigger several diseases in humans and animals, since antimicrobial resistance bacteria, as well as antimi...

Open access Research Article 10.9734/jammr/2025/v37i45794

Anti-arthritic Potential of Alocasia macrorrhizos Aqueous Extract in an Adjuvant Induced Arthritis Model

Allyne Aparecida Dias da Silva Castro, Roberta Mello Cachuba, Wagner de Fatima Pereira, Vinícius Neves Paiva Oliveira, Gabriela de Paula Carli, Alessandra de Paula Carli, Sandra Bertelli Ribeiro de Castro & Caio César de Souza Alves · Journal of Advances in Medicine and Medical Research · 2025

Rheumatoid arthritis is a chronic, inflammatory and autoimmune disease characterized by joint inflammation and systemic manifestations. This study aimed to evaluate the therapeutic potential of Alocasia macrorrhizos (EAAm) aqueous extract in an Adjuvant-Induced Arthritis (AIA) mo...

Open access Research Article 10.9734/jammr/2025/v37i45790

Photobiomodulation Therapy Reduces Inflammation and Improves Skin Flap Survival in Animal Model

Erika Aparecida Felix de Barros Pinto, Alexandre Jin Book Audi Chang, Deiwet Ribeiro Silva, Rodrigo Labat Marcos, Ana Paula Ligeiro de Oliveira, Jose Antonio Silva Junior & Stella Regina Zamuner · Journal of Advances in Medicine and Medical Research · 2025

Photobiomodulation, a noninvasive and efficient technique, has the potential to improve microcirculation and promote neovascularization. Therefore, photobiomodulation has emerged as a promising method for reducing the risk of skin flap necrosis. This study aimed to evaluate the e...

Open access Research Article 10.9734/jammr/2025/v37i45791