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All published articles 6159

Testiculo Protective Effects of Ethanolic Roots Extract of Pseudocedrela kotschyi on Alloxan Induced Testicular Damage in Diabetic Rats

A.O. Ojewale, O. T. Olaniyan, F. A. Faduyile, O. A. Odukanmi, J. A. Oguntola & B. J. Dare · Journal of Advances in Medicine and Medical Research · 2013

Aims: The study was designed to investigate the testiculo protective effects of ethanolic roots extract of Pseudocedrela kotschyi on alloxan-induced testicular damage in diabetic rats. Study Design: Experimental diabetes using animal models. Place and Duration of Study: Departmen...

Open access Research Article 10.9734/BJMMR/2014/5680

Alkaline Phosphatase Isoenzymes and Leukocyte Alkaline Phosphatase Score in Patients with Acute and Chronic Disease: A Brief Review

Aurelian Udristioiu, Radu G. Iliescu, Manole Cojocaru & Adela Joanta · Journal of Advances in Medicine and Medical Research · 2013

Aims: To conduct a review of the literature concerning existing methods to detect alkaline phosphatase (ALP) in human serum and to examine the dietary factors that modulate ALP-intestinal isoenzyme (IAP) activity, in light of new findings about its additional functions. Backgroun...

Open access Research Article 10.9734/BJMMR/2014/3309

Morphine Treatment in Neonate Rats Increases Exploratory Activities: Reversal by Antagonist D2 Receptor

Joanna R. Rozisky, Gabriela Laste, Liciane F. Medeiros, Vinicius S. dos Santos, Lauren S. Adachi, Isabel C. de Macedo, Wolnei Caumo & Iraci L. S. Torres · Journal of Advances in Medicine and Medical Research · 2013

Aims: Morphine treatment in early life is a practice widely used in paediatric intensive care units. However, the consequences of this treatment on behavioural responses throughout life have been poorly studied. It is well known that behavioural symptoms after morphine exposure a...

Open access Research Article 10.9734/BJMMR/2014/3586

The Effect of the Oral Bacterial Extract OM-85 BV on Asthma Control- a Prospective Study

Antonios Christopoulos, Lilia Pandeli & Panagiotis Demopoulos · Journal of Advances in Medicine and Medical Research · 2013

Aims: To identify the effect of the oral bacterial extract OM-85 on essential parameters of asthma control. Study Design: This was a double blind, prospective study, consistent of a 4 week run-in and a 24 week double blind period. Place and Duration of Study: An outpatient clinic...

Open access Research Article 10.9734/BJMMR/2014/4458

Biomass Fuel Use and Risk of Cataract: Systematic Review and Meta-Analysis

Hemant Kulkarni, Uday W. Narlawar, Neelam D. Sukhsohale, Sushama Thakre & Suresh N. Ughade · Journal of Advances in Medicine and Medical Research · 2013

Aims: There is an increasing recognition of the putative association between the use of biomass fuels and the risk of cataracts. However, the exact strength of this association is currently unknown. Our aim was to synthetically quantify the association between biomass fuel use an...

Open access Research Article 10.9734/BJMMR/2014/5297

Hospital Evacuation; Learning from the Past? Flooding of Bangkok 2011

A. Khorram-Manesh, C. Angthong, A. Pangma, S. Sulannakarn, R. Burivong, R. Jarayabhand & P. Örtenwall · Journal of Advances in Medicine and Medical Research · 2013

Aims: To evaluate hospital evacuation in light of recent hospital evacuations in Bangkok and surrounding areas. This information was compared with results reported in the literature. Study Design: Retrospective and qualitative. Place and Duration of Study: Bangkok, Thailand, Dece...

Open access Research Article 10.9734/BJMMR/2014/5059

Potential Autoepitope within the Extracellular Region of Contactin-Associated Protein-like 2 in Mice

Demian F. Obregon, Yuyan Zhu, Antoinette R. Bailey, Samantha M. Portis, Huayan Hou, Jin Zeng, Saundra L. Stock, Tanya K. Murphy, Michael A. Bengtson & Jun Tan · Journal of Advances in Medicine and Medical Research · 2013

Aims: Implicated in autoimmune encephalitis, neuromyotonia and genetic forms of autism, here we report that contactin-associated protein-like 2 (CNTNAP2) contains a potential autoepitope within the extracellular region. Methodology: CNTNAP2 sequence-similar regions (CSSRs) from h...

Open access Research Article 10.9734/BJMMR/2014/6135

Isolated Nodular Ischemic Infarcts: A Central Lesion That Presents as Peripheral Vertigo

Leonard LL Yeo, Hock L. Teoh, Rahul Rathakrishnan, Gavin HT Lim, Eric Ting & Vijay K. Sharma · Journal of Advances in Medicine and Medical Research · 2013

Aims and Objective: Giddiness is one of the commonest presenting complaints to the emergency physicians. Differentiation between ‘peripheral’ and ‘central’ etiologies is important to avoid unnecessary investigations and avoid missing a potentially serious diagnosis such as an isc...

Open access Research Article 10.9734/BJMMR/2014/5688

Brachial Artery Flow Mediated Vasodilatation Changes in Endothelium Due to Hyperuricemia in Type 2 Diabetes Mellitus

Parineeta Samant & Padma Chavan · Journal of Advances in Medicine and Medical Research · 2013

Aim: This study aims to evaluate serum uric acid levels and assess its effect on endothelial dysfunction by measuring flow mediated vasodilatation (FMD) of brachial artery in type 2 diabetes mellitus. Study Design: Observational and prospective Place and Duration of Study: The st...

Open access Research Article 10.9734/BJMMR/2014/5487

Alteration of Testicular Macrophage Morphology and Associated Innate Immune Functions in Cadmium Intoxicated Swiss Albino Mice

Sumana Chakraborty & Mahuya Sengupta · Journal of Advances in Medicine and Medical Research · 2013

Aims: The present study investigates in a mouse model the extent of immunomodulatory effects after exposure to cadmium chloride (in vivo) in the testes. Study Design: Experimental study. Place and Duration of Study: Department of Biotechnology, Assam University, Silchar, Assam, I...

Open access Research Article 10.9734/BJMMR/2014/5498

Polymorphisms in Interleukin-2 and Interleukin-7 Receptor α-Chain Genes and Human Herpes Virus-6 as Risk Factors for Multiple Sclerosis

Layal Fayad, Aline Kherlopian, Alexander M. Abdelnoor, Bassem Yamout & Elias A. Rahal · Journal of Advances in Medicine and Medical Research · 2013

Aim: The aim of this study was to examine whether a Human herpes virus-6 (HHV-6) infection increases the risk of MS in individuals harboring particular cytokine receptor α-chain gene alleles. Study Design: MS patients and controls were assessed for HHV-6 DNA and for single nucleo...

Open access Research Article 10.9734/BJMMR/2014/5550

Pre-operative Serum Albumin and Neutrophil-Lymphocyte Ratio are Associated with Prolonged Hospital Stay Following Colorectal Cancer Surgery

Rohit Gohil, Majed Rishi & Benjamin H. L. Tan · Journal of Advances in Medicine and Medical Research · 2013

Aims: Colorectal cancer is the third most common cancer in European populations. It has been shown previously that neutrophil-lymphocyte ratio (NLR), pre-operative albumin, and haemoglobin are useful prognostic indicators. The aim of this study was to assess how these factors inf...

Open access Research Article 10.9734/BJMMR/2014/5444

Lipid Peroxidation and Glutathione Peroxidase in Acute Myocardial Infarction

David Gangte, Davina Hijam, Asitava Roy, Sonam Tashi Dolma, Lalnunpuii . & Th. Ibetombi Devi · Journal of Advances in Medicine and Medical Research · 2013

Aims: To evaluate the level of lipid peroxidation (by measuring malondialdehyde) and endogenous antioxidant enzyme (glutathione peroxidase) in acute myocardial infarction. Study Design: Cross sectional study. Place and Duration of Study: Department of Biochemistry in collaboratio...

Open access Research Article 10.9734/BJMMR/2014/5283

Antinociceptive Effect of Ethanolic Extract of Hybanthus enneaspermus Leaf in Rats

A. O. Afolabi, E. T. Oluwakanmi, H. M. Salahdeen, A. O. Oyekunle & I. A. Alagbonsi · Journal of Advances in Medicine and Medical Research · 2013

Aims: To test the hypothesis that Hybanthus enneaspermus leaf has an antinociceptive effect. Methodology: Seventy-two male rats were randomly divided in a blinded fashion into 4 groups each for the tail immersion test (n=12 per group) and formalin test (n=6 per group). Group 1 (c...

Open access Research Article 10.9734/BJMMR/2014/4217

Proteomic Biomarker Discovery: Review of the Science and Its Challenges with Clinical Samples

T. Hussain, L. Scaife, V. Hodgkinson, J. P. Kneeshaw, M. Lind, P. Drew & L. Cawkwell · Journal of Advances in Medicine and Medical Research · 2013

Proteomics is a science that facilitates global analysis of protein expression, molecular interactions and functional states of protein in a cell, organ or organism under consideration. Protein at the molecular level represents the biological endpoint and therefore more suitable...

Open access Research Article 10.9734/BJMMR/2014/5268