This project reviewed gene mutations which are associated with BRCA1 and BRCA2. From epidemiological perspective, the escalating cost of breast cancer management is due to the aging phenomenon of the female cohort in United States population. Innovative genomic sequencing techniq...
Open access
Research Article10.9734/BJMMR/2011/478
This review brings together and analyzes the problem of zinc effects on the body through apoptosis, also affecting the latest data in the study of process itself apoptosis. Also, the possibility of using zinc and its derivatives and its complexes in cancer treatment are discussed...
Open access
Research Article10.9734/BJMMR/2011/488
The study was undertaken to evaluate the possible role of Androgen Receptor (AR) in relation to tumor grade, age, sex and urinary bladder cancer risk. Expression of AR detected by immunohistochemistry in 125 Transitional Cell Carcinoma and 100 control cases. Expression of AR was...
Open access
Research Article10.9734/BJMMR/2011/304
Aims: To highlight an uncommon situation during stenting for obesity surgery complications. Place and Duration of Study: 1st Propaideutic Surgical Unit, Hippokration Hospital, Athens between December 2008 and November 2010. Results: 2 cases of obese patients are presented where t...
Open access
Research Article10.9734/BJMMR/2011/288
The incidence of obesity has significantly increased worldwide. Surgery has proven to be the most effective long-term treatment for sustained weight loss and improvement of co-morbidities in morbidly obese patients. Laparoscopic sleeve gastrectomy (LSG) is a relatively new proced...
Open access
Research Article10.9734/BJMMR/2011/417
Dermatitis herpetiformis (DH) is an autoimmune blistering disorder associated with a gluten-sensitive enteropathy (GSE), and is generally accepted as a cutaneous manifestation of celiac disease and is characterized by grouped excoriations; erythematous, urticarial plaques; and pa...
Open access
Research Article10.9734/BJMMR/2011/364
Aims: Soluble cytokeratin (CK) fragments and inflammatory interleukins (ILs) in bone marrow (BM) aspirates of colorectal cancer (CRC) patients are expected to indicate presence of disseminated tumor cells (DTCs) and anticancer response of the host, respectively. The present study...
Open access
Research Article10.9734/BJMMR/2011/508
Retroviral vectors based upon the Moloney murine leukemia virus (MLV) have been used due to their high efficiency of stable gene transfer. Core binding factors (CBF) are heterodimeric transcription factors containing a DNA binding Runx 1, Runx 2, or Runx 3 subunit, along with a n...
Open access
Research Article10.9734/BJMMR/2011/483
Aim: This study was designed to enhance the scope of sputum analysis by using it as a clinical tool in gene/protein expression, by making the paraffin embedded blocks. Methodology: The specimens were prepared as smear and cell blocks for cytopathologic examination. The preparatio...
Open access
Research Article10.9734/BJMMR/2011/421
This project investigated genomic epidemiology of congestive heart disease, the clinical and non-invasive techniques for diagnosis and the modifiable and non-modifiable risk factors associated with the disease were explored. Trends in the morbidity and mortality of CHD revealed a...
Open access
Research Article10.9734/BJMMR/2011/629
A set of embryonic proteins - potential markers for ovarian tumors is presented. More than ten new embryonic proteins have been tested, but no one strictly specific protein marker for diagnosis of ovarian tumors has been revealed. SOVA-1 is the most perspective marker for today....
Open access
Research Article10.9734/BJMMR/2011/344
Objective: Postmenopausal women usually experience symptoms related to vasomotor instability due to a decline in estradiol levels. Certain plants have been found to have components that are same in structure and function to female estrogen and progesterone. This study conducted t...
Open access
Research Article10.9734/BJMMR/2011/163
Background: Down Syndrome (DS) is the most frequent chromosomal abnormality in live births with an incidence of 1 to 1.7 per 1,000 births and a variable physical expression. Down syndrome screening has been an integral part of routine prenatal care in recent decades. Currently, t...
Open access
Research Article10.9734/BJMMR/2011/317
The study evaluated the effect of combined extracts of Vernonia amygdalina (VA) and Gongronema latifolium (GL) on the pancreas of streptozotocin (STZ) induced diabetic Wistar rats. Thirty-two (32) albino rats were divided equally into 4 groups. Groups A and B which served as norm...
Open access
Research Article10.9734/BJMMR/2011/215
Aim/Background: The present study was planned to evaluate the antidiabetic activity of ‘Folk recipe’ a combination of traditional medicinal plants in normoglycemic and alloxan-induced diabetes rabbits. The level of antioxidant activity was determined by DPPH in relation to the to...
Open access
Research Article10.9734/BJMMR/2011/245