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All published articles 1382

Ashwagandha and Its Active Ingredient, Withanolide A, Increase Activation of the Phosphatidylinositol 3’ Kinase/Akt Cascade in Hippocampal Neurons

Dahae Hwang, Isabel Vasquez, Leticia Galvez, Huong Do, Anthony Lopez de Santa Ana, Shane Matta, Feimeng Zhou, Michael Chen & Amelia Russo-Neustadt · European Journal of Medicinal Plants · 2017

Aims: To determine if whether, in a hippocampal neuron culture model subjected to nutrient deprivation stress (simulating degenerative disease state), Ashwagandha and/or two of its putative active ingredients, withanolide A or withaferin A, affect any of the following: neurite ou...

Open access Research Article 10.9734/EJMP/2017/35355

Antidiabetic Activities of the Aqueous Root Bark and Flower Extracts of Terminalia catappa on Streptozotocin - Induced Diabetes in Male Wister Rats

Comfort Japhet Philip, Luka D. Carrol, Ishaya Y. Longdet & Aguiyi J. Chinyere · European Journal of Medicinal Plants · 2017

Diabetes mellitus is a disease associated with the increase in Blood glucose level caused by the abnormalities of glucose receptors in the uptake of glucose or total destruction of the β pancreatic cell, with approximately 366 millions of people worldwide diagnosed with the disea...

Open access Research Article 10.9734/EJMP/2017/34702

The Effect of Hydroalcoholic Extract of Ferulago angulata on Liver Function Parameters and Antioxidant Status in Alloxan-Induced Diabetic Rats

Seyedeh-Fatemeh Mousavi-Ezmareh, Mohammad Mazani, Esfandiar Heidarian, Reza Alipanah Moghadam, Mahmoud Rafieian-kopaei, Garshasp Mardanian, Lotfollah Rezagholizadeh & Ali Shamsazar · European Journal of Medicinal Plants · 2017

Aim: The aim of this study was to evaluate the hepatoprotective and antioxidant activities of Ferulago angulata Extract (FAE) in experimental diabetic rats. Materials and Methods: 54 adult male Wistar rats divided into 6 groups (n=9). Diabetes was induced in all animals except th...

Open access Research Article 10.9734/EJMP/2017/35134

Anti-microbial Activities of Selected Ghanaian Medicinal Plants and Four Structurally Similar Anti-protozoan Compounds against Susceptible and Multi-drug Resistant Bacteria

A. N. Antwi, K. B. A. Owusu, M. Amoa-Bosompem, N. B. Williams, F. Ayertey, L. Akyeh, J. Agyapong, T. Tetteh, G. I. Djameh, S. K. Botchie, F. Azerigyik, A. Ablordey, N. H. Tung, A. A. Appiah, T Uto, S. Iwanaga, Y. Shoyama, N. Ohta, B. Egyir & M. Ohashi · European Journal of Medicinal Plants · 2017

Antibacterial resistance is one of the fast rising health concerns globally. WHO emphasized the need for development of new drugs to combat antimicrobial resistance. Our group previously found several anti-protozoan compounds: ML-2-3, Molucidin and ML-F52 from a Ghanaian medicina...

Open access Research Article 10.9734/EJMP/2017/35437

Effect of Methanolic Leaf Extract of Carica papaya on Plasmodium berghei Infection in Albino Mice

Ishaya Y. Longdet & Emmanuel A. Adoga · European Journal of Medicinal Plants · 2017

Aim: The work was designed to investigate the antmalarial activity of methanolic leaf extract of Carica papaya on Plasmodium berghei NK65 strain infection in vivo. Place and Duration of Study: Department of Biochemistry and National Institute of Pharmaceutical Research and Develo...

Open access Research Article 10.9734/EJMP/2017/34698

Therapeutic Effect of Nigella sativa on Alcohol-induced Liver Disease in Rats

A. Mosbah, H. Zettal, H. Khither, C. Mosbah, N. Kacem Chaouche & M. Benboubetra · European Journal of Medicinal Plants · 2017

Background: Alcohol-induced fatty liver disease is the earliest liver disorder associated with excessive consumption of alcohol. Various treatment regimens have been proposed for the treatment of alcohol-induced liver disorders including the use of medicinal plants such as Nigell...

Open access Research Article 10.9734/EJMP/2017/34661

Investigation of Antioxidant Activity and Cytotoxic Effect of Stem of Anthocleista djalonensis

Oyinlade C. Ogundare, S. M. Akoro, Abiodun O. Ogunfowora & Adekunle Oladunni · European Journal of Medicinal Plants · 2017

Aim: To investigate the antioxidant and cytotoxic activities of stem of A. djalonensis. Study Design: The study assessed the antiradical potential of the stem bark of A. djalonensis and determined the cytotoxic effect of the plant extracts using Allium cepa root growth inhibition...

Open access Research Article 10.9734/EJMP/2017/33803

Recipes and Treatments in Traditional Herbal Medicine to the Kaamba Community of Madingou, Congo

Victor Kimpouni, Josérald Chaîph Mamboueni, Marie-Yvette Lenga-Sacadura & Elie Nsika Mikoko · European Journal of Medicinal Plants · 2017

Aims: Studying the recipes in popular use of medicinal plants by Kaamba community settled in savannah and their analyses. Study Design: It highlights the socio-cultural basis of this society through phytotherapeutic data. Place and Duration of Study: The ethnobotanical study was...

Open access Research Article 10.9734/EJMP/2017/35096

Modulation of Cytochrome C Release and Opening of Mitochondrial Permeability Transition Pore by Calliandra portoricensis (Benth) Root Bark Methanol Extract

T. Olubukola Oyebode, O. Tolulope Adebusuyi, S. Emmanuel Akintimehin & O. Olufunso Olorunsogo · European Journal of Medicinal Plants · 2017

Aim: Evasion of apoptosis, a form of programmed cell death, is a common feature of most cancer cells. This study evaluated the modulatory effects of different fractions of crude methanol extract of the root bark of Calliandra portoricensis, a medicinal plant used in the tradition...

Open access Research Article 10.9734/EJMP/2017/35211

Ethnomedicinal Information and Phytochemical Screening of Medicinal Plants Used in the Treatment of Diarrhea in Lagos State, Nigeria

O. J. Sharaibi & O. S. Osuntogun · European Journal of Medicinal Plants · 2017

Aim: To identify and screen the phytochemicals of medicinal plants with anti-diarrhea potential in Lagos State, Nigeria.   Place and Duration of the Study: Ethnobotanical survey and phytochemical screenings of plants used in traditional medicine for the treatment of diarrhea in N...

Open access Research Article 10.9734/EJMP/2017/26815

Antitrypanosomal Activity of Allium porrum Ethyl Acetate Bulb Extract in Trypanosoma brucei brucei Experimentally Infected Wister Albino Rats

S. Odeyemi Omonike, A. Umar Yahaya & M. S. Abdulsalami · European Journal of Medicinal Plants · 2017

Aims: The present study investigated the antitrypanosomal activity of crude ethyl acetate bulb extracts of A. porrum plant against T. b. brucei. Methodology: Twenty five male albino rats were divided into five groups and infected with x106/ml of T. b. brucei. Group 1 was infected...

Open access Research Article 10.9734/EJMP/2017/34418

Antiplasmodial Potential and Phytochemical Screening of Ten Plants Used as Antimalarial in Mali

Mamadou WELE, Laura Kirkman, Nouhoum Diarra, Yaya Goita, Moriba Doumbia, Kassim Traore & Drissa Diallo · European Journal of Medicinal Plants · 2017

Aim: This study was designed to determine in vitro antiplasmodial activities of extracts from ten Malian medicinal plants against P. falciparum strains. Place and Duration of Study: Collection of plant materials and basic phytochemical screening were done in Bamako, Mali and anti...

Open access Research Article 10.9734/EJMP/2017/34523

Evaluation of Molluscicidal Activity of Croton microstachyus and Cissus quadrangularis against Biomphalaria and Bulinus Species of Snails

Eyob Y. Garoy, Tsegezeab Goje, Dawit Mebrahtu, Atul Kaushik, Robel Asfaha, Amanuel Andemariam, Dawit Brhane, Ermias Efream, Kiros Teweldebrhan & Zere Araya · European Journal of Medicinal Plants · 2017

Aim: The study was carried out to investigate the molluscicidal activities of different solvent extracts of two Eritrean local plants, Croton macrostachyus and Cissus quadrangularis identified using ethno-botanical, pharmacological information and also traditional use gathered fr...

Open access Research Article 10.9734/EJMP/2017/33560

Renal Protective Properties of Aqueous Extract of Bryophyllum pinnatum (Lam.) Oken Leaf against Petrol Vapour – Induced Toxicity on Male Albino Rats

Friday O. Uhegbu, Caleb J. Nwaogwugwu, Chibuzo H. Onwuegbuchulam, Chinwe Edith Oriaku, Okechukwu C. Atasie & Kelechi U. Akatobi · European Journal of Medicinal Plants · 2017

The aim of this study was to investigate the renal protective properties of aqueous leaf extract of Bryophyllum pinnatum from Nigeria against petrol vapour – induced toxicity on the kidney of male albino rats. Fifty apparently healthy male albino rats aged 8 weeks and weighing be...

Open access Research Article 10.9734/EJMP/2017/33358

Phytochemical Screening, Antifungal and Antibacterial Effect of Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum Used in Traditional Medicine in Yamboro (Central African Republic)

E. Kosh-Komba, L. Aba Toumnou, I. Zinga, I. Touckia, P. U. Nembara Zin Wogbia Lembo, G. Mukeina, S. Semballa, O. D. Yongo & J. L. Syssa-Magale · European Journal of Medicinal Plants · 2017

The knowledge of traditional medicine has always guided the search for new cures. Zanthoxylum zanthoxyloides and Zanthoxylum macrophylum, (Rutaceae) are used as medicinal plants in Central African Republic for bacteria and fungi treatment. The aim of this study is to investigate...

Open access Research Article 10.9734/EJMP/2017/33304