Aims: This study evaluated the diagnostic accuracy of the IL-10/TNF-alpha ratio, TNF-alpha alone, and neutrophil percentage for distinguishing HIV-malaria co-infection from malaria-only and HIV-only mono-infection among adults in Warri, Delta State, Nigeria. Study Design: Hospita...
Open access
Research Article10.9734/ibrr/2026/v17i4406
Background: Thrombosis is a multifactorial condition in which inherited thrombophilic abnormalities, acquired haemostatic disturbances, and other clinical factors may coexist and contribute to thrombotic susceptibility. Because multiple abnormalities can occur within the same ind...
Open access
Research Article10.9734/ibrr/2026/v17i4405
Oluwaseyi Adeteju Adeyanju, Richard Peter Akpan, Mitchelle Akanbi, Adetunji Oladapo Adewale, Adebukola Temilade Adeyanju & Olusegun Taiwo Oke·International Blood Research & Reviews·2026
Background: Sickle cell anaemia involves interconnected haemolytic, inflammatory, and haemostatic disturbances that may persist beyond overt crisis. Aims: To compare a combined five-parameter profile—lactate dehydrogenase (LDH), C-reactive protein (CRP), prothrombin time (PT), in...
Open access
Research Article10.9734/ibrr/2026/v17i4404
Ngengang Venceslas Mohmoh, Achidi Eric Akum, Marie Ebob Agbortabot Bissong, Tiku Helen Nda, Gaitan Fabrice Njiomegnie, Ngo Biyong Njike Olive & Agnes Mbiaya Mbeng Obi·International Blood Research & Reviews·2026
Background: Regular screening for irregular antibodies is an important prerequisite for safe blood transfusion. However, most blood banks in sub-Saharan Africa, including Cameroon, do not routinely screen for these antibodies or the Kell antigen. This study aimed to determine the...
Open access
Research Article10.9734/ibrr/2026/v17i4403
Adebola Shakirat Akinbile, Richard Akpan, Adesola Helen Oniye, Abdulkabir Abiodun Fasasi, Kehinde Akeem Adegoke, Adetola S. Oshi, Arowolo Ayokanmi Daniel, Ajani Olanrewaju Oyetunde, Adesina Beatrice Ebun & Amusan Festus Olatubosuna·International Blood Research & Reviews·2026
Aims: To determine trimester-specific reference intervals and compare glycated haemoglobin (HbA1c), fasting plasma glucose (FPG) and full blood count (FBC) parameters between second- and third-trimester non-diabetic pregnant women. Study Design: Cross-sectional comparative study....
Open access
Research Article10.9734/ibrr/2026/v17i4402
Background: Pregnancy is associated with physiological changes in haemostasis that may vary across gestation. Aims: To assess prothrombin time (PT), activated partial thromboplastin time (aPTT), and platelet count across the three trimesters of pregnancy and compare these paramet...
Open access
Research Article10.9734/ibrr/2026/v17i4401
Background: Storage of whole blood is accompanied by biochemical and cellular changes that may alter soluble adhesion molecules. This study evaluated serum concentrations of vascular cell adhesion molecule-1 (VCAM-1), intercellular adhesion molecule-1 (ICAM-1), and P-selectin dur...
Open access
Research Article10.9734/ibrr/2026/v17i4400
Sickle cell disease is a systemic vasculopathy in which intravascular haemolysis, endothelial activation, leukocyte and platelet recruitment, and coagulation activation operate as a single self-reinforcing process now commonly described as thromboinflammation. Most of the mechani...
Open access
Research Article10.9734/ibrr/2026/v17i4399
Background: Evidence concerning the relationship of ABO blood groups with metabolic markers remains inconsistent, particularly among apparently healthy young adults. Aim: To determine the relationship between ABO blood groups, fasting blood glucose, and serum uric acid levels amo...
Open access
Research Article10.9734/ibrr/2026/v17i4398
Background: Lassa fever is a viral haemorrhagic illness endemic to Nigeria and other West African countries. Severe cases are often associated with abnormal coagulation and impaired platelet function. Objective: This study primarily assessed coagulation parameters and examined th...
Open access
Research Article10.9734/ibrr/2026/v17i4397
Inflammation is inseparable from blood-cell biology: circulating cells detect inflammatory cues, bone-marrow progenitors alter lineage output, erythroid iron supply is actively restricted, and haemostatic pathways can be recruited as components of host defence. Yet the expression...
Open access
Research Article10.9734/ibrr/2026/v17i4396
Background: Routine haematological and biochemical indices support monitoring of adults with HIV, but geographical variation in Rivers State is insufficiently described. Aims: To compare blood count indices, inflammatory cell ratios, biochemical parameters and physical indicators...
Open access
Research Article10.9734/ibrr/2026/v17i4395
Background: Nigeria is home to more than two million people living with HIV, yet it remains underrepresented in HIV vaccine trials. Peripheral blood mononuclear cells (PBMCs) are vital for assessing vaccine-induced immunity; however, biobanking in resource-limited settings presen...
Open access
Research Article10.9734/ibrr/2026/v17i4394
Background: Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disorder characterised by persistent synovial inflammation and progressive joint damage. Aim: This study assessed selected autoimmune and inflammatory biomarkers among individuals with RA in Port Harcourt,...
Open access
Research Article10.9734/ibrr/2026/v17i4393
Background: Male reproductive dysfunction is increasingly relevant in chronic anaemias as survival into adulthood has improved in β-thalassaemia and sickle cell disease, while iron-deficiency anaemia remains globally common. Impaired fertility arises through hypoxia, oxidative st...
Open access
Research Article10.9734/ibrr/2026/v17i4392