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All published articles 384

Convalescent Plasma for COVID-19- is it Time to Say Goodbye? A Single-Center, Retrospective, Observational Study from Northern India

Rasika Setia, Mitu Dogra, Gokhula Prasath Thangavel, Ramesh Yadav, Amena Ebadur Rahman, Atul Bhasin, Rajesh Kumar Pande, Sandeep Nayar, R. K. Singal, Anil Vardani, Deepak Gargi Pande, R. N. Saini, Tribhuvan GulatI, Vivek Pal Singh, Sunny Kalra, Gagan Anand, Manish Garg, Santosh Ghai & N. M. Agarwal · International Blood Research & Reviews · 2021

Background: COVID-19 pandemic continues threatening the world with no effective treatment to tackle the menace. Till date, there is conflicting evidence on efficacy of CP in reducing COVID-19 related mortality. The objective of this study was to see disease progression and 7, 14...

Open access Research Article 10.9734/ibrr/2021/v12i430158

Overview of Adverse Events Associated with Anti-CD19 Chimeric Antigen Receptor T-Cell Therapy

Ekaterina Vorozheikina, Magdalena Ruiz, Leticia Solari, Dmitry Ostasevich & Luis Mendoza · International Blood Research & Reviews · 2021

Anti-CD19 chimeric antigen receptor (CAR) T-cells represent a novel immunotherapy that has shown remarkable success in the treatment of adult relapsed or refractory (R/R) B-cell non-Hodgkin's lymphoma, adult R/R mantle cell lymphoma, and R/R acute paediatric lymphoblastic leukaem...

Open access Research Article 10.9734/ibrr/2021/v12i430157

Hypocholesterolemia and Statins in Multiple Myeloma

Irfan Yavasoglu & Atakan Turgutkaya · International Blood Research & Reviews · 2021

Statins are lipid-lowering agents. They also have immunomodulatory, anti-inflammatory, anti-angiogenic, and anti-proliferative functions. In this context, they are demonstrated to have beneficial effects on mortality in several malignancies including esophageal, breast, lung, liv...

Open access Research Article 10.9734/ibrr/2021/v12i430156

Coronavirus: A Laboratory Perspective

Ransom Baribefii Jacob, Chukwu Christopher Ifunaya & Emeji Roseline · International Blood Research & Reviews · 2021

COVID-19 is a virus of the species of the Family coronaviridae known as as SARS-COV-2. This virus is easily contracted and/transmitted from an infected person to another healthy individual and has continued to spread rapidly. The aim of this review is to identify laboratory metho...

Open access Research Article 10.9734/ibrr/2021/v12i430155

Informed Consent in Transfusion Medicine: An Ethical Obligation Or a Legal Compulsion to Avert Liabilities for Negligence to the Health Care Provider

Orkuma, Joseph Aondowase, Edward E. Ogar, Esq, Ayia, Nyiutsa George, Joseph Ojobi & Gomerep Samuel Simji · International Blood Research & Reviews · 2021

Blood transfusion is oftentimes life-saving but associated with risks which ought to be disclosed by the health care provider as an ethical obligation and legal requirement. The practice of informed consent to transfusion medicine is quite new and few studies have comprehensively...

Open access Research Article 10.9734/ibrr/2021/v12i330154

Survival in Patients with Acute Lymphoblastic Leukemia and COVID-19 in Mexico

Patricia Zagoya Martinez, Jose Alejandro Limon Flores & Jose Alfredo Vidal Vidal · International Blood Research & Reviews · 2021

Aims: To determine the survival of patients with acute lymphoblastic leukemia and COVID-19. Study Design: Prospective, analytical and relational. Place and Duration of Study: Hematology department, Hospital of Specialties, High Specialty Medical Unit, National Medical Center "Gra...

Open access Research Article 10.9734/ibrr/2021/v12i330153

Assessment of Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria Based on ABO/Rhesus Blood Groups Distribution

J. E. Wenah-Emmanuel, E. M. Eze, E. O. Nwachuku, E. Wenah & Z. A. Jeremiah · International Blood Research & Reviews · 2021

Aim: The aim of this study was to assess the Gene Frequencies of Human Platelet Alloantigens in Rivers-State, Nigeria based on ABO/Rhesus blood groups distribution Study Design:   A randomized controlled trial. Place and Duration of Study: Rivers State University Medical Centre,...

Open access Research Article 10.9734/ibrr/2021/v12i330152

Performance Evaluation: Four Chemiluminescent SARS-Cov-2 Immunoassays and Rapid-Card Test in Mild Disease and Seroprevalence of SARS CoV-2 in Frontline Healthcare Workers

Rasika Setia, Mitu Dogra, Anil Handoo, Gokhula Prasath Thangavel, Ramesh Yadav, Purabi Barman, Raj Kumar Kapoor & Amena Ebadur Rahman · International Blood Research & Reviews · 2021

Introduction: The COVID-19 pandemic raised a host of challenges to modern medicine. Key amongst these were in diagnostics, as most SARS-CoV-2 assays had been rapidly developed and released under emergency-use authorization with limited validation on clinical samples and secondly,...

Open access Research Article 10.9734/ibrr/2021/v12i330151

Chronic Lymphocytic Leukemia in an Adolescent Girl: A Case Report and Clinico-Pathologic Review

Neelum Mansoor, Naeem Jabbar, Hamza Khan, Ameerah Shaikh & Saba Jamal · International Blood Research & Reviews · 2021

Chronic lymphocytic leukemia (CLL) in pediatric age is rare in the literature. It is a common disease of older adults, characterized by clonal proliferation and progressive accumulation of monoclonal B-cell lymphocytes. The diagnosis is established by immunophenotyping and progno...

Open access Research Article 10.9734/ibrr/2021/v12i330150

Serum Antioxidant Enzymes, Haematological Values and Uric Acid Concentrations in Prostatic Disease Patients: An Investigative Study

Agbugba N. Agnes, Ohaeri O. Christopher, Ijioma N. Solomon, R. I. Uroko, Achi K. Ngozi & Nwaogazi N. Edith · International Blood Research & Reviews · 2021

Aim: In this study, the haematology, serum antioxidant enzymes, and uric acid concentrations in prostatic disease patients attending the Nephrology Department of Abia State University Teaching Hospital, Aba were evaluated. Methodology: A total of one hundred and ten (110) adult m...

Open access Research Article 10.9734/ibrr/2021/v12i230149

Medical Students and the Level of Their Knowledge on Normal Flora: Results from an Electronic Questionnaire Conducted in a Private Medical School

Forman Erwin Siagian & Lusia Sri Sunarti · International Blood Research & Reviews · 2021

Introduction: So far, study on medical student’s knowledge regarding human normal flora is not available in the internet. Normal flora is initially beneficial for their host, but what was once part of the normal flora can later become dangerous to their host, e.g become the agent...

Open access Research Article 10.9734/ibrr/2021/v12i230148

Evaluation of Changes in Haematological Parameters of Sickle Cell Anaemia Subjects in Rivers and Bayelsa States

B. S. Mbeera, S. O. Akwuebu, A. C. U. Ezimah, N. C. Ibeh & E. M. Eze · International Blood Research & Reviews · 2021

Aim: The aim of this study was to evaluate changes in some haematological parameters in sickle cell anaemia subjects in Rivers State. Study Design:  This study is a cross-sectional observational study. Place and Duration of Study: University of Port Harcourt Teaching Hospital, Ri...

Open access Research Article 10.9734/ibrr/2021/v12i230147

Which Strategy to Manage Severe Vaso-occlusive Crisis in Patients with Sickle Cell Disease in Countries with Limited Healthcare Capacities?

Lydie Ocini Ngolet, Chelsea Jayne Bango, Peggy Mawandza & Alexis Elira Dokekias · International Blood Research & Reviews · 2021

We evaluated the treatment of morphine by intravenous patient controlled analgesia versus intermittent subcutaneous routes on patients with sickle cell disease developing severe vaso-occlusivecrisis. Objectives: The primary objective was to compare intravenous patient controlled...

Open access Research Article 10.9734/ibrr/2021/v12i230146

Anemia: Considerations for the Dental Practitioner

Georges Aoun, Pamela Aoun, Wissam Sharrouf & Abbass El-Outa · International Blood Research & Reviews · 2021

Anemia is a condition of decreased red blood cell number or hemoglobin concentration, or of disturbance in their function, ultimately leading to decreased oxygen transport to tissues. Many factors and diseases may lead to anemia, with wide manifestations systemically as well as o...

Open access Research Article 10.9734/ibrr/2021/v12i230145

Interaction between Phagocytic Cells with Antiphagocytic Properties of Cryptococcus neoformans: When Love and Hate Collide

Forman Erwin Siagian · International Blood Research & Reviews · 2021

Global systemic fungal infection, including meningeal cryptococcosis caused by the encapsulated yeast Cryptococcus spp, continue to rise in number, especially among HIV infected individuals. Infection occur through inhalation of spore which is abundant in the environment. Initial...

Open access Research Article 10.9734/ibrr/2021/v12i130144