Aim: To evaluate the frequency and prognostic impact of DNA methyltransferase 3A (DNMT3A) gene mutation on response to induction therapy in newly diagnosed acute myeloid leukemia patients. Study Design: Cross-sectional descriptive study. Place and Duration: Hematology units of Su...
Open access
Research Article10.9734/IBRR/2018/44030
Aim: To determine the level of Salmonella agglutinin and its titre among apparently healthy students of Tertiary Institution in North-eastern Nigeria. Study Design: A cross-sectional study on Seroprevalence of Salmonella agglutinin; Place and Duration of the Study: Department of...
Open access
Research Article10.9734/IBRR/2018/43362
Patients with acute myeloid leukaemia (AML) who have FMS-like tyrosine kinase 3 (FLT3) mutations are a concern for haematologists. Many studies indicate that these patients have poor prognosis. Due to the dearth of research in this area, the role of allogeneic transplantation as...
Open access
Research Article10.9734/IBRR/2018/42466
Background: The pattern and distribution of haematological malignancies vary depending on age, sex and geographical location. Studies on the association between haematological cancers and ABO blood types have been largely conflicting. Aim: To determine the frequency and distribut...
Open access
Research Article10.9734/IBRR/2018/42665
Introduction: Administration of blood and blood products is very life-saving. However, the safety of blood transfusion in resource-limited nations is questionable unlike in many developed nations of the world. The risk of viral transmission has been significantly curtailed, but b...
Open access
Research Article10.9734/IBRR/2018/42233
Taofeeq Oduola, Faruq Bunza, Monsurat Temitope Yusuf, Muhammed Kabiru Dallatu, Muhammed Alhaji Ndakotsu, Abubakar Panti, Ben Onankpa & Adesoji Adeniji·International Blood Research & Reviews·2018
Background: Glucose-6-phosphate dehydrogenase deficiency is one of the most common enzyme defects affecting all races and particularly in malaria-endemic areas. This study aimed at determining G6PD deficiency, bilirubin and oxidative stress biomarkers in G6PD deficient neonates a...
Open access
Research Article10.9734/IBRR/2018/42009
Aim: This study aimed to estimate the normal CD4 counts in healthy Bhutanese blood donors. Study Design: A prospective descriptive study. Place and Duration of Study: This study was carried out in the Jigme Dorji Wangchuck National Referral Hospital (JDWNRH), Thimphu, between Jul...
Open access
Research Article10.9734/IBRR/2018/41946
Background: Antiphospholipid antibodies (aPLs) are the serological markers used in the diagnosis of the antiphospholipid syndrome (APS). HIV infection has been associated with an elevated aPls level, but its link to the APS with clinical thrombosis is still been investigated. Thi...
Open access
Research Article10.9734/IBRR/2018/41710
Aims: To observe any diversity of pattern in the anaemic parameters in the major ethnic groups of Pakistan. Study Design: Observational, cross-sectional. Place and Duration of Study: Department of Medicine, Creek general Hospital, Korangi, Karachi, Pakistan from October 2017 to M...
Open access
Research Article10.9734/IBRR/2018/42073
Introduction: A Transfusion transmitted infection (TTI) is a virus, parasite, or other potential pathogen that can be transmitted in donated blood through a transfusion to a recipient. This transmission is one of the most dreaded complications of blood transfusion. Aims and Objec...
Open access
Research Article10.9734/IBRR/2018/41271
Aim: To highlight the diagnosis of haemophilia B in 5 Nigerian brothers as well as the diagnostic and management challenges inherent in resource-poor settings. Presentation of Cases: We report the cases of 5 brothers with ages ranging from 2 years to 13 years seen at the paediatr...
Open access
Research Article10.9734/IBRR/2018/40474
S. Azonbakin, B. Houssou, I. Azannai, B. Awede, R. MassI, M. Adjagba, A. Agbalinsou, L. Anani, R. Darboux, F. Gangbo & A. Laleye·International Blood Research & Reviews·2018
Chronic myelogenous leukaemia (CML) is an acquired myeloproliferative disorder (MPD) characterized by a chromosomal abnormality (the Philadelphia chromosome) that causes the chimeric BCR-ABL oncogene. An acquired genetic mutation in exon 12 of the JAK2 tyrosine kinase gene leadin...
Open access
Research Article10.9734/IBRR/2018/39436
S. Abubakar, O. Erhabor, I. Z. Issac, A. B. Ibrahim, Van Dyke Knox, S. Yuguda, A. Girei, S. Adamu, A. Saidu, M. Bello & B. H. Tilako·International Blood Research & Reviews·2018
Sickle cell disease is a global public health problem. L-arginine is an amino acid that helps in improving blood in the arteries of the heart and improved symptoms of clogged arteries, chest pain or angina and coronary arteries disease. Nitric oxide is a powerful neurotransmitter...
Open access
Research Article10.9734/IBRR/2018/39769
The therapeutic benefits of camel milk consumption are a supplement to routine sickle cell disease management. In maintaining hemolytic crises in sickle cell anaemia, patients were assessed during a six weeks study. Throughout the study, 20 patients were recruited for the study a...
Open access
Research Article10.9734/IBRR/2018/38776
Aims: To assess the overall performance of the transfusion-transmissible infection testing laboratory through the evaluation of the results obtained from the participation in a blood proficiency testing study (B-PTS). Study Design: The B-PTS study was designed, organized and cond...
Open access
Research Article10.9734/IBRR/2017/38371