Blood group typing has changed more in the past three decades than in the preceding hundred years. What began as an exercise in observing agglutination reactions has become, increasingly, an exercise in reading DNA: a shift from describing antigens as they appear on the red cell...
Open access
Research Article10.9734/ibrr/2026/v17i4391
Kouamé Norman Isaac Klébair, Kamara Ismael, Assohou Hiabba Emmanuela, Atseye Chiadon Carele Charlene, Kouadio Emmanuel, Boidy Kouakou & Gustave Kouassi Koffi·International Blood Research & Reviews·2026
Spontaneous non-traumatic epidural haematoma is an uncommon but potentially fatal neurological complication of sickle cell disease. This case report describes a 13-year-old girl with homozygous sickle cell disease who was admitted with a non-febrile vaso-occlusive crisis after in...
Open access
Research Article10.9734/ibrr/2026/v17i4390
Chiemelie Raluchukwu Onwasigwe, Michael Chidiebele Egolum, Angela Ogechukwu Ugwu & Hector Okechukwu Obianyido·International Blood Research & Reviews·2026
Background: Non-Hodgkin lymphoma is a heterogeneous group of lymphoid malignancies with variable clinical behaviour and treatment outcomes. In resource-constrained settings, limited access to advanced prognostic investigations increases the need for simple biomarkers. This study...
Open access
Research Article10.9734/ibrr/2026/v17i3389
Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi·International Blood Research & Reviews·2026
Hemoglobinopathies (e.g., HbS, HbC, HbF) are the most common single-gene disorders worldwide, especially in sub-Saharan Africa. Beyond affecting red blood cells and oxygen transport, they significantly disrupt blood clotting (hemostasis) and blood flow properties (haemorheology)....
Open access
Research Article10.9734/ibrr/2026/v17i3388
Ndudi Dibigbo–Ibeaji, Sylvia Ifeoma Obu, Gabriel Obisike Obu, Samuel Okwuchukwu Ilikannu, Akinkunmi Ibukun Jacob & Ezunu Ngozi Esther·International Blood Research & Reviews·2026
Background: Pancytopenia reflects a failure of normal hematopoiesis or excessive destruction or sequestration of blood cells and is frequently associated with significant morbidity and mortality if not promptly identified and managed. Despite growing global recognition of the sys...
Open access
Research Article10.9734/ibrr/2026/v17i3385
Background: Hypertension is a leading modifiable risk factor for cardiovascular disease, and midlife is a critical period when adverse systolic blood pressure (SBP) trajectories emerge. We estimated nationally representative associations between SBP and demographic, socioeconomic...
Open access
Research Article10.9734/ibrr/2026/v17i3386
Adenuga Jacob Olaitan, Olusegun Taiwo Oke, Muhibi Musa Abidemi, Adesina Beatrice Ebun, Olatunji Oluwatobi, Ajao Oluwadare Amos & M. B. Ajayi·International Blood Research & Reviews·2026
Reference intervals, the statistically defined ranges of physiological parameter values expected in a healthy reference population, constitute a cornerstone of clinical laboratory medicine. In haemorheology, reference intervals for whole blood viscosity, plasma viscosity, erythro...
Open access
Research Article10.9734/ibrr/2026/v17i3387
Background: Maternal alloimmunisation against the RhD antigen remains a preventable cause of haemolytic disease of the foetus and newborn (HDFN), a condition responsible for substantial perinatal morbidity and mortality in resource-limited settings. Population-specific data on Rh...
Open access
Research Article10.9734/ibrr/2026/v17i3384
Blood group antigen variability has significant implications for transfusion safety and prevention of alloimmunization, particularly in multi-ethnic populations where antigen expression may differ. This study investigated the distribution of Kell and Duffy blood group antigens am...
Open access
Research Article10.9734/ibrr/2026/v17i2383
Background: Hydroxyurea is the most accessible disease-modifying therapy for sickle cell disease (SCD), but in many low- and middle-income countries its real-world benefit is constrained by gaps in awareness, uptake, continuity, and adherence. We analyzed the full hydroxyurea pat...
Open access
Research Article10.9734/ibrr/2026/v17i2382
Uterine fibroid is a common gynaecological condition that affects the health of women globally. This cross-sectional study evaluated the levels of some haemostatic parameters in women with uterine fibroid. The study involved 240 subjects who were within the ages of 20 and 45 year...
Open access
Research Article10.9734/ibrr/2026/v17i2381
Jacques Forwah Ndeh, Ushie Godwin Abua, Edung Emem Samuel, Ogochukwu Chinwoke Etoniru, Chukuamaka Iweze Ifukor, Chiamaka Vianney Ndimele, Edung Catherine, Worship Tega Ewhrudjakpor, Akpojovwo Esther Ufuomanefe, Chinedum Sam Iheukwumere, Aishatu Omoragbon, Abayomi Oluwatobi Opadijo, Felix Nsofor, Ibuje Taghogho Emuobo, Amahan Anne, Kelechi Chukwuemeka Nwaozuzu, Ekwueme Michael Chibueze, Kunna Ugaliegbulam, Chuba Ifedigbo, Edeani Bobby David, Ewa Anthony Obi, Etukemo Ubong Amos, Idiege Idiege Omang, Ofonime Benjamin Essien, Ngha James Ngah, Ofor Joshua Obase-Otumoyi, Immaculate Ihuoma Ekeagba, Akpojivi Bridget Ejiroghene, Joel Danladi Bala & Abeshi Sylvester Etenikang·International Blood Research & Reviews·2026
The detection of alcohol use history amongst potential blood donors is crucial to ensure the safety of the blood supply. Traditional laboratory-based testing methods have shown to have some limitations namely lengthy turnaround times and high costs. Emerging direct and specific a...
Open access
Research Article10.9734/ibrr/2026/v17i2380
Gianluca Gessoni, Giulia de Fusco, Giovanni Roveroni, Carla Rossi, Gabriella Mazzaro, Lauretta Moro, Gianni Tidore, Marta Siviero, Giovanni Carretta, Domenico Bagnara, Raffaella Berti & Silvia da Ros·International Blood Research & Reviews·2026
Background: In contemporary healthcare systems, the sustainability of complex care models increasingly depends on the transition toward decentralized frameworks. Community-based transfusion therapy have emerged as a strategic approach to ensure continuity of care for frail and ch...
Open access
Research Article10.9734/ibrr/2026/v17i2379
Dysmenorrhea is a common gynecological condition marked by recurrent menstrual pain, predominantly affecting females of reproductive age. The immune system is intricately connected to menstrual cycle regulation, and various endogenous and exogenous factors can alter the leukocyte...
Open access
Research Article10.9734/ibrr/2026/v17i1378
Venous thrombosis is a life threatening disease associated with high morbidity and mortality. Predisposing factors of venous thrombosis associated with obesity, age, varicose veins etc. There is an interaction between the thrombosis and inflammation. P selectin unregulated glycop...
Open access
Research Article10.9734/ibrr/2026/v17i1377