Aims and Objectives: High performance liquid chromatography which is basically an Ion Exchange Chromatography, is the most popular as well as expensive method for glycated hemoglobin estimation but biased results have been observed in hemoglobinopathies. Sometimes results cannot...
Open access
Research Article10.9734/IBRR/2016/24410
Aim of the Study: Acute myeloid leukemia (AML) is a heterogeneous clonal stem cell malignancy characterized by proliferation of immature hematopoietic cells. Adipokines in particular leptin and adiponectin are highly active molecules that attracted considerable interest due to th...
Open access
Research Article10.9734/IBRR/2016/23857
N. N. Njoku-Oji, C. V. Nwike, U. Dimkpa, N. O. Ifegwu, L. C. Anike, S. O. Maduka, O. A. Sobanke & R. C. Uchefuna·International Blood Research & Reviews·2016
Objective: This work was carried out to investigate the effects of oral administration of aqueous leaf extract of Ficus capensis on some hematological parameters in albino rats. Methodology: Twenty-eight normal male rats weighing between 180-240 g were used for this study. They w...
Open access
Research Article10.9734/IBRR/2016/23083
Pandanus tectorius of the family Pandanaceae is a medicinal plant that grows in Nigeria. The Pandanus tectorius extract was tested for; its acute toxicity using mice and, its antioxidant activities (using DPPH spectrometic assay, anti-lipid peroxidation activity and Nitric oxide...
Open access
Research Article10.9734/IBRR/2016/22231
The aqueous extract of Hibiscus sabdariffa leaves is popularly consumed in the form of “Zobo” drink in Nigeria and it is assumed to have haematological benefits. The present study was conducted to evaluate the effects of aqueous extract of H. sabdariffa leaves on possible changes...
Open access
Research Article10.9734/IBRR/2016/23170
Introduction: Progesterone and Estrogen are the chief pregnancy hormones. Their levels increase during pregnancy to aid successful maintenance of pregnancy, which depends on maternal tolerance of the fetal semi allograft. Aim: To determine levels of progesterone and 17β-estradiol...
Open access
Research Article10.9734/IBRR/2016/22508
The blood collected from a new born baby umbilical cord is known as Cord blood. It is a rich source of hemotopoietic stem cells, used in the treatment of over 80 diseases like various cancers and blood, immune and metabolic disorders. Cord blood is collected from umbilical cord v...
Open access
Research Article10.9734/IBRR/2015/22377
Background / Aims: Efforts are put into making blood safe for the recipient and non-injurious to the donor, and to avoid wastage of blood but blood is oftentimes wasted. This pilot study assessed the rate and reasons for blood wastage in the hospital blood bank of a developing co...
Open access
Research Article10.9734/IBRR/2015/22739
The study was tailored to investigate changes in all haematological parameters of diabetic rats treated with methanol root bark extract of Cussonia arborea. A total of 72 male albino wistar rats assigned into 6 groups of 12 rats per group were used. Groups 1-5 were made diabetic...
Open access
Research Article10.9734/IBRR/2015/22725
Background: Transfusion Transmitted Infections (TTIs) threaten safety of the recipients and the community as a whole and are the subject of real concern worldwide. Human immunodeficiency virus (HIV) causes Acquired Immunodeficiency Syndrome (AIDS) which can affect people of any a...
Open access
Research Article10.9734/IBRR/2015/21631
Aim: The literature does not include sufficient data on the hematological inflammation markers in acne vulgaris. The present study aimed to investigate potential of neutrophil/lymphocyte ratio, platelet/lymphocyte ratio, and mean platelet volume as inflammatory markers in acne vu...
Open access
Research Article10.9734/IBRR/2015/21905
K. N. Ngbolua, Rafatro Herintsoa, Rakotoarimanana Hajatiana, V. Mudogo, D. D. Tshilanda, D. S. T. Tshibangu & P. T. Mpiana·International Blood Research & Reviews·2015
Aims: To evaluate the antisickling activity of lunularic acid. Study Design: Biological experiment in vitro (Emmet test), evaluation of cell morphological parameters such as radius, perimeter and surface. Place and Duration of Study: University of Kinshasa, Democratic Republic of...
Open access
Research Article10.9734/IBRR/2015/21718
Aim: The study was undertaken to assess the fibrinolytic activity during pregnancy and to determine the effects of maternal age, gestation period and parity on fibrinolytic parameters in Northern Nigeria. Materials and Methods: 150 pregnant and 100 non-pregnant women, aged 17-40...
Open access
Research Article10.9734/IBRR/2015/18389
Eustace B. Berinyuy, Bashir Lawal, Amuzat A. Olalekan, Ibrahim A. Olalekan, Abubakar A. Yusuf, Sani Sakpe & Prince C. Ossai·International Blood Research & Reviews·2015
Background: Cassia occidentalis has been used in traditional medicine since prehistoric times and it’s now known to be a natural medicine with many beneficial effects, Objective: The present study aimed at evaluating the effects of methanol extract from this plant on haematologic...
Open access
Research Article10.9734/IBRR/2015/22021
Glucocorticoid (GC) resistance has been demonstrated in nearly 30% of primary immune thrombocytopenia (ITP) patients even managed with high dosages GC. The biological effects of GC are mainly mediated through activation of glucocorticoid receptors (GR). An insight into the molecu...
Open access
Research Article10.9734/IBRR/2015/20213