Introduction: The ABO blood group system is the most clinically recognized and routinely investigated blood group system in donated blood used for transfusions in Sub-Saharan Africa, due to its immunogenicity and the potential for antibodies against ABO antigens to cause the dest...
Open access
Research Article10.9734/ibrr/2024/v15i4346
Haematological malignancy constitutes a major public health disease burden globally due to the degree of mortality and morbidity they cause. Aim: This review was aimed at exploring and reporting some of the difficulties that hinder early/accurate diagnosis and management of haema...
Open access
Research Article10.9734/ibrr/2024/v15i4345
The present study needs to assess the plasma levels of calcium, creatinine and blood glucose among hypertensive patients in Edo State, Nigeria in order to ascertain whether plasma levels of these parameters are associated with hypertension in this population which will provide im...
Open access
Research Article10.9734/ibrr/2024/v15i4344
Background: CD38 is a protein highly expressed on myeloma (MM) cells that has been shown to be an effective target antigen for monoclonal antibody therapies, so treatment with anti-CD38 monoclonal antibodies is a first line therapy for patients with MM. Although CD38 is weaker ex...
Open access
Research Article10.9734/ibrr/2024/v15i3343
Eclampsia is always considered as a very serious complication of pregnancy which is responsible for numerous maternal and perinatal mortality in global setting. Eclampsia is characterized by seizures in a pregnant or postpartum patient as a result of hypertension. It is an escala...
Open access
Research Article10.9734/ibrr/2024/v15i3342
Oluomachi C Nnachi, Innocent P Ezenwenyi, John C Akulue, Oji A Nnachi, Favour E Nwadum, Tochukwu J Onoh, Ozioma E Ezeokoli & Chima G Ugwu·International Blood Research & Reviews·2024
Background: The haemostatic system maintains a balance between prothrombotic and antithrombotic components in the body. The role of this system in ischaemic stroke is not certain. Objective: Prothrombin time (PT) and Activated Partial Thromboplastin Time(APTT) are widely used scr...
Open access
Research Article10.9734/ibrr/2024/v15i3341
Background: Regular blood donation which decreases blood iron levels may protect against cardiovascular diseases (CVD). This protection against atherosclerosis can be assessed by Carotid Intima-Media Thickness (CIMT) a biomarker for atherosclerosis. This study sought to determin...
Open access
Research Article10.9734/ibrr/2024/v15i3340
Background: Few reports have been published about the current clinical management of anti-Kell alloimmunization in pregnancy; its low frequency of occurrence means that the few long series published have covered an extensive time period in which different treatment approaches ha...
Open access
Research Article10.9734/ibrr/2024/v15i3339
Introduction: Blood transfusion is a life-saving procedure best carried out as soon as it is recommended to avoid morbidity and mortality. Aim: To determine the Pattern, complications and social problems of blood transfusion in a neonatal unit in Southern Nigeria. Methodology: A...
Open access
Research Article10.9734/ibrr/2024/v15i2338
Background: A considerable number of RHD alleles responsible for weak and partial D phenotypes have been identified. Serological determination of these phenotypes is often doubtful and makes genetic analysis of RHD gene highly desirable in transfusion recipients and pregnant wome...
Open access
Research Article10.9734/ibrr/2024/v15i2337
Background: There is a thin line between a safe blood transfusion and transfusion-related fatality hence the need to be diligent in every aspect of the blood transfusion process. Appropriate and complete documentation on a blood transfusion request form is one of the most importa...
Open access
Research Article10.9734/ibrr/2024/v15i2336
The study investigated the effects of vitamin C on platelet parameters, white blood cell count and white blood cells differentials in Wistar rats exposed to lead acetate. A total of twenty-four male Wistar rats weighing between 160g and 200g were utilized. The experimental animal...
Open access
Research Article10.9734/ibrr/2024/v15i2335
Background: D-Dimer is considered a pivotal biomarker in diagnosis of disseminated intravascular coagulation and in differential diagnosis of thrombosis and pulmonary embolism. Case Summary: BL, Caucasian woman, 81 years old, was admitted to hospital, in October 2023, for concuss...
Open access
Research Article10.9734/ibrr/2024/v15i2334
Tatiana Baglo, Alban Zohoun, Bienvenu Houssou, Romaric Massi, Charlotte Orou Guiwa, Ludovic Anani, Dorothée Kindé Gazard & Awa Omar Touré Fall·International Blood Research & Reviews·2024
Aim: determine the prevalence of a FVIII inhibitors and identify the genetic mutations associated with their development in beninese personne with hemophilia (PwH) A. Study Design: this is cross-sectional descrptive study conducted from June 2022 to May 2023 in hemophilia treatme...
Open access
Research Article10.9734/ibrr/2024/v15i1333
Background: Sickle cell anemia is a disease that affects largely Africans and people in the tropics. It affects an average of 7.74 million and the mortality rate was 376,000 in the year 2021. Sickle cell disease was discovered in 1910 by a Famous scholar Herrick who described it...
Open access
Research Article10.9734/ibrr/2024/v15i1332