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All published articles 889

In vitro Analysis of the Pharmaceutical Interactions between Verapamil Hydrochloride and Citric Acid

Kazi Aysha Akter, Md. Mohiuddin Rahaman Rakib, Mokta, Mst Nasrin Khatun & Maliha Monoara Oafa · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The objective of this study is to investigate the combination of drug-drug interactions involving different functional groups by assessing the interaction of a BCS class IV compound (Verapamil Hydrochloride) with Citric acid in various ratios, thereby enhancing the understanding...

Open access Research Article 10.9734/jamps/2025/v27i2748

Administration of Exosome-based Treatment for Exogenous Ochronosis Caused by Prolonged Use of Topical Hydroquinone

Danielle Karen Widjaja, I Made Winarsa Ruma, I Gusti Ayu Widianti & Vania Kwanda · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Objective: Exogenous ochronosis is a rare but challenging skin condition caused by prolonged misuse of hydroquinone-containing creams, with limited effective treatments. This study aimed to evaluate the effectiveness of exosome-based therapy as a novel therapeutic approach for th...

Open access Research Article 10.9734/jamps/2025/v27i2747

Preclinical Evaluation of the Anti-inflammatory Properties of Plants Extracts of Ficus exasperata (Moraceae) on Wistar Rat Models

Bate Antuan Asue, Edith Lem Abongwa, Vanessa Tchadji Mayoudom, Bayaga Herve Narcisse, Ndikum Valentine, Lovet Benyella Fokunang, Njinkio Nono Borgia, Estella Tembe-Fokunang, Bathelemy Ngameni, Sameh Abouzid & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: In view of the rising global death rate associated with inflammatory diseases, a cost friendly, more effective and, safer drug with lesser side effects is needed.  Inflammation is a part of the complex biological response of vascular tissue to harmful stimuli, such...

Open access Research Article 10.9734/jamps/2025/v27i1746

Innovative Approaches in Glioblastoma Treatment: The Role of Optune in Enhancing Patient Survival

Ashvin Kumar, Nicholas Truong & Rahul Jandial · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Glioblastoma multiforme (GBM) is the most common form of malignant primary brain and CNS (central nervous system) tumors in adults. Prognosis is generally poor and the current standard for treatment often fails to meet expectations. In recent years, Optune has garnered attention...

Open access Research Article 10.9734/jamps/2025/v27i1745

Evaluation of Anticancer, Thrombolytic and Antimicrobial Activities of Heliotropium indicum (Indian turnsole)

Kazi Fabliha Anjum, Al Farabe, Abu Jubaer Asif, Khadizatul Kubra & Khandaker Antara Anika · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

This research objective was to investigate some in vitro properties of methanol-extracted plant extracts of Heliotropium indicum (Indian turnsole). The primary method of assessment for the methanolic extract of Heliotropium indicum (MEHI) was investigated for phytochemical screen...

Open access Research Article 10.9734/jamps/2025/v27i1744

Impact of Integrated Interventions of Prescriber Education and De-escalation Strategies on Implementing WHO Access: Insights from a South Indian Tertiary Care Setting

Jasper Victoria Leelarani Martinraj, Harini. S, S. Bibila, Feba Mary Thomas & Keren Ann George · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: This study evaluates the effect of integrated interventions including prescriber education and de-escalation strategies on improving antibiotic prescribing practices, optimizing the Access: Watch ratio, reducing Reserve antibiotic use, and improving Length of Therapy (LOT)...

Open access Research Article 10.9734/jamps/2025/v27i1743

Comparison of Patients’ Perceptions of Safety and Efficacy of Herbal and Conventional Type 2 Diabetes Treatments in Nairobi, Kenya

Monicah W. Karara, Faith Apolot Okalebo, Peter K. Ndirangu & Sylvia A. Opanga · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Use of herbal medicines is common among patients with type 2 diabetes in Kenya. Studies on patient-reported efficacy and safety of these medicines are lacking. Aims: To determine and compare satisfaction with safety and efficacy of medicines among patients with type 2...

Open access Research Article 10.9734/jamps/2025/v27i1742

Evaluation of the Antimalarial Activity of Garcinia kola Ethanolic Extracts in the Prevention and Treatment of Plasmodium berghei-infected Mice

Philemon Babylon, Rebecca Salau Napthtali, Wama Binga Emmanuel & Atimi Atinga · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

The present study aimed to evaluate of the anti-malarial activity of Garcinia kola (bitter kola) nut and leaf ethanolic extracts in Treatment of Plasmodium berghei-infected Mice. The two plant parts were collected from its natural breeding site and were processed in the laborator...

Open access Research Article 10.9734/jamps/2024/v26i12741

Obesity: Pathophysiology, Health Implications, and Therapeutic Interventions

Subhra Swaraj, Sheetal Sarraf, Subhranshu Panda & Sadia Parveen · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Obesity is a significant health issue defined by the excessive accumulation of fat that poses serious health risks. A Body Mass Index (BMI) exceeding 24 is categorised as overweight, while a BMI over 30 is considered obese. Obesity is a major contributor to various chronic diseas...

Open access Research Article 10.9734/jamps/2024/v26i12738

Goji Berry (Lycium barbarum) Extract as a Potential Anti-Photoaging Agent: A Literature Review

Lena Margaretha Sutikno, I Wayan Sugiritama & I Wayan Juli Sumadi · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Tropical countries worldwide are frequently subjected to high levels of sunlight year-round. This leads to concerns about potential harmful effects, including skin damage resulting from oxidative stress caused by free radicals due to prolonged sun exposure. This results in extrin...

Open access Research Article 10.9734/jamps/2024/v26i12739

Protective Effect of Annona muricata Leaf Extract against Electrolytes Imbalance in Wistar Rats Induced with Acute Myocardial Infarction

Oladejo, A.A., Okeke, C.B., Okeke C.M., Iloanya, E. L., Adeyemi, M. A., Anyanwu, R. O., Apalowo, D. & Onyenweaku, O. G. · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Annona muricata, a tropical fruit known for its medicinal properties, has been investigated for its potential cardioprotective effects, particularly in treating acute myocardial infarction (AMI), a critical condition caused by blocked coronary arteries. This study investigates pr...

Open access Research Article 10.9734/jamps/2024/v26i12737

Assessment of the Effects of Stone Herbal Mixture Drink on Liver Parameters

Usiobeigbe O.S., Iyevhobu, K.O., Obohwemu K.O., Omolumen L.E., Idehen I.C., Asibor E., Udoaka, A., Adeji A.J., Ikede R.E., Omoviye O.E., Lagundoye S.B., Echekwube M.E. & Isiaka S.T. · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Background: Herbal treatments have been used for ages, across many countries and traditions to maintain health and treat diseases. Herbal medicines are sometimes seen as all-natural substitutes for traditional drugs, providing a possible means of advancing health and fitness. Inv...

Open access Research Article 10.9734/jamps/2024/v26i12736

Evaluation of Antiarthritic Protective Effect of Erlangea tomentosa (Oliv. & Hiern) S. Moore (Asteraceae) Methanol Leaf Extract in Complete Freund’s Adjuvant-Induced Arthritis in Rats

Anselme Mboneye, Albert Nyanchoka Onchweri, Timothy Neeza & Saidi Odoma · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Objective: Given the rising interest in plant-based therapies for chronic inflammatory diseases like arthritis, this study aimed to explore the potential of Erlangea tomentosa, a plant known for its medicinal properties, as an anti-arthritic agent Methodology: The plant extract w...

Open access Research Article 10.9734/jamps/2024/v26i12735

Anti-oxidant Assessment of Parsonsia straminea (R.Br) F. Muell Stem Bark Crude Extract

Ozakieoniso James Kemelayefa, Bonsome Bokolo & Precious Awipi · Journal of Advances in Medical and Pharmaceutical Sciences · 2024

Background:  Parsonsia straminea a member of the Apocynaceae family with ancestral record from Australia especially at the tropical region of New South Wales and Queensland has been scientifically been proven for its anti-seizure, anti-narcoleptic potentials, and traditionally us...

Open access Research Article 10.9734/jamps/2024/v26i12733