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All published articles 889

Assessment of Some Brain Antioxidants Profile in Plasmodium berghei berghei Infected Mice Treated with Ethanol Leaf Extract of Musa paradisiaca

Adebayo Olugbenga Adegoke, Ben Sandy Odeghe, Ibitoroko Maureen George-Opuda, Abimbola Temitayo Awopeju, Kemzi Nosike Elechi-Amadi & Emmanuella Chidiebere-Onwukwe · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background and Aim: This study evaluated brain antioxidants of locally formulated herbal antimalarial therapy, dry plantain leaf extract (Musa paradisiaca) on mice infected with Plasmodium berghei. Experimental Procedure: Five groups of ten mice each namely control, P. berghei, a...

Open access Research Article 10.9734/jamps/2023/v25i3608

Synthesis and Determination of Antimicrobial Efficacies of Secondary Metabolite of Streptomyces longisporoflavus and its 3D-Protein Structural Prediction

Olusola Nathaniel Majolagbe, Felicia Oguntunji, Ezekiel Gbadebo Adeyeni, Yetunde Mutiat Feruke-Bello & Louis Odinakose Ezediuno · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Aims: The need for new drug molecules is of high significance considering the rate at which pathogenic bacteria evolve into drug-resistant pathogens. Actinomycetes have been reported as valuable biological agents that possess potent bioactive molecules. This work aims to isolate...

Open access Research Article 10.9734/jamps/2023/v25i3605

Patterns of Computed Tomography Urography Findings in a Tertiary Hospital in Rivers State: 2 Years Retrospective Study

Vivian Ndidi Akagbue, Chidinma Wekhe, Mary-Jane Orevaoghene Amadi & Ebbi Donald Robinson · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Computed tomography urography (CTU), is a radiological examination and has largely replaced traditional intravenous urography (IVU) as the gold standard in the imaging of the genitourinary tract, hence it is now used as a primary imaging technique to evaluate patients...

Open access Research Article 10.9734/jamps/2023/v25i3604

Pharmacognostic Evaluation and Hepatoprotective Property of Crude and Fractions of Triumfetta cordifolia A. Rich. (Tiliaceae)

Chikeokwu Ikenna, Ene Erica Chiamaka, C. Mba Theodora & Uche Estella Odoh · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: The role of phytochemicals in modern medicine is abundant with more evidence being published. Triumfetta cordifolia is a local plant known for its vast medicinal applications in traditional medicine with limited documented evidence. This study thus aims to evaluate th...

Open access Research Article 10.9734/jamps/2023/v25i3603

The Effect of Heavy Metal Contaminants in Some Herbal Cosmetics on Cardiovascular Risk Indices of Rabbits

Brown Holy, N. I. Thompson & E. Adu Matthew · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Cosmetics are ornamental products used in the improvement of the physical outlook of either the face or skin. These may be synthetic or natural depending on the source of production. Herbal cosmetics have gained prominence in our daily lives due to the belief that the...

Open access Research Article 10.9734/jamps/2023/v25i2602

Acute Seizure Following Isotretinoin Administration: A Detailed Case Report

May Alsane, Adnan Hajjiah & Alasmar El-Shably · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Isotretinoin is considered a cutting edge treatment for Acne vulgaris. It is licensed for treating severe (cystic) acne vulgaris. Our case report represents a 28 year old female who experienced a rare neurological side-effect after ingesting Isotretinoin.

Open access Research Article 10.9734/jamps/2023/v25i2601

The Growing Threat of Antibiotic Resistance: Addressing the Urgency

Hania Haque, Syed Irtiza Imam, Hareer Fatima, Syeda Dua E. Zehra Zaidi, Burhanuddin Sohail Rangwala & Hussain Sohail Rangwala · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Antibiotic resistance has become a critical public health issue due to the overuse and misuse of antibiotics. Despite ongoing efforts to develop stronger antibiotics, bacterial resistance continues to evolve, leading to a global crisis. Effective antibiotics are becoming scarce,...

Open access Research Article 10.9734/jamps/2023/v25i2600

Comparative Study of the Antibacterial and Cytotoxic Activity of Leaves, Trunk and Roots of Schumanniophyton Magnificum

Thérèse Essonkene, Gisèle Marie Marguerite Etame Loe, Cécile Okalla, Jules Clement Assob Nguedia & Jean Emmanuel Mbosso Teinkela · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Aims: Schumanniophyton magnificum is a plant reputed traditionally to treat numerous urogenital infections linked to several germs, notably: Escherichia coli, Staphylococcus aureus, Neisseria gonhorhea, Treponema palidum, Candida albican. This study aims to evaluate and compare t...

Open access Research Article 10.9734/jamps/2023/v25i2599

Microbiology of Chronic Suppurative Otitis Media amongst Children Attending a Tertiary Health Facility in North-Western Nigeria

Mfon Ime Inoh, Elizabeth Enene Inoh, Yahaya Mohammed, Kufre Robert Iseh, Semen Stephen Yikawe & Nasiru Aliyu · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Chronic suppurative otitis media (CSOM) is a global middle ear disease worst in developing nations of the world. The burden in our environment of repeated episodes of childhood CSOM, and the resultant difficulty in the management of these patients because of improper...

Open access Research Article 10.9734/jamps/2023/v25i2598

Coagulation Parameters among Individuals with Hepatitis B Infections in Okada, Edo State, Nigeria

Mitsan Olley, Sule Zekeri, Aghatise Kevin Erhamwonyi, Maureen Uchechukwu Okwu, Aiyanyor David Osayomwanbo, Osaiyuwu Osarenren Clement & Izevbuwa Osazee Ekundayo · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Hepatitis B Viral (HBV) infection is a condition of inflammation of the liver. The Liver plays a vital role in the body which includes filtration of the blood, production of coagulation proteins and also as a storage organ. In this study, alteration of some coagulation parameters...

Open access Research Article 10.9734/jamps/2023/v25i1597

siRNA: A Comprehensive Review of Marketed Products till August 2022

Rupali Ghosh, Md. Iqbal Hossain Nayan & Tirtha Nandi · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Small interference RNA (siRNA) is a double-stranded RNA of 21~25 nucleotides. siRNA functions using a natural phenomenon known as RNA interference (RNAi), a gene silencing mechanism. Hypothetically, siRNA can target and regulate the expression of any disease-related gene in a seq...

Open access Research Article 10.9734/jamps/2023/v25i1596

The Impact of Delayed Separation of Plasma and Serum Sample on Glucose Parameter of Apparently Healthy Students of Federal School of Medical Laboratory Technology (Science), Jos, Nigeria

Ukeme Sambo Abara, Imoh Etim Ibanga, Lucy Larrycarr Nwapi, Matina Imaobong Ekpo, Hilary Andrew Akpan, Obinna Nkechi, John Okon Mkpani, Nduese Innocent Joseph, Nanle Ibrahim Konglam, Brendan Chukwueke Nkwocha & Manji Bala Dalen · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Estimation of glucose is very important in clinical diagnosis of diabetes mellitus, hyperglycemia and hypoglycemia. The core aim of clinical laboratory service is to produce accurate, precise and reliable test results. The ability of laboratories to do this lies in th...

Open access Research Article 10.9734/jamps/2023/v25i1595

Factors Associated with Unmet Needs for Family Planning among People Living with HIV/AIDS in the South-South Region of Nigeria

Ifeoma C. Ofurum, Onyinye G. Mba & Cosmos E. Enyindah · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Background: Family planning is an important part of reproductive health which assists couples and individuals to make decisions regarding the timing, spacing, as well as the number of desired children. For individuals living with HIV, this can be challenging, as assess to reprodu...

Open access Research Article 10.9734/jamps/2023/v25i1594

Heavy Metals Contamination of Rice and Soil Samples in Nnatu St Azuuiyi Udene, Abakiliki, Ebonyi State, Nigeria

Helen Anthony Waribo, Ngozi Bernadette Ohakwe, E. O. Anyalebechi, Daye Mandy George & Ebirien-Agana Samuel Bartimaeus · Journal of Advances in Medical and Pharmaceutical Sciences · 2023

Aim: Assess  the levels of heavy metals: arsenic (As), cadmium (Cd), copper (Cu), lead (Pb), and zinc (Zn) in three different sites of the major rice growing soils and determine  its accumulation in the rice grown on the same site in Nnatu St Azuuiyi Udene, Abakiliki, Ebonyi Stat...

Open access Research Article 10.9734/jamps/2023/v25i1593

Practices and Barriers towards Pharmacovigilance and Adverse Drug Reporting among Intern Pharmacists in Nigeria

Shadrach Chinecherem Eze, Evaristus Chinonso Odoh, Kingsley Chinemerem Eze, Wisdom Enyinnaya Arugo, Gerald Obinna Ozota, Ugomma Loveth Anyaji, Collins Chukwuemeka Magbo, Chidimma Elizabeth Mbakamma, Victor Chikaodiri Amaechi, Chimaobi Jude Nwiyi, Kennedy Onyedikachi Ijegalu & Goodness Chizorom Nwokebu · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: The practice of Pharmacovigilance (PV) and Adverse Drug Reaction (ADR) reporting is very necessary to ensure adequate safety of all drugs in use and is an integral component of post marketing surveillance. Pharmacist, including interns are at a central position in car...

Open access Research Article 10.9734/jamps/2022/v24i11587