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All published articles 889

Antimicrobial Resistance: Unexplained Failure to Antibiotic Therapy in a Case at Maluti Adventist Hospital Berea Lesotho

Lineo Nyenye & Azubuike Benjamin Nwako · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: The aim of the present study was to highlight the presence and problem of antimicrobial resistance in our setting. Case Presentation: We present a 17-year old female with yellow offensive vaginal discharge, itchiness and lower abdominal pain of about two-weeks duration. She...

Open access Research Article 10.9734/jamps/2022/v24i630305

Congenital Heart Malformations in Iraq, a Review

Luma Ibrahim Khalel Al-Allaf & Rawa Younis Mahmmod · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: Heart malformations are among the commonest indications for admission to hospital and may causes mortality of children. There is a need to highlight this important medical issue as there is no review article on this subject in Iraq. Aim: This study aims to focus on th...

Open access Research Article 10.9734/jamps/2022/v24i530303

Cardiovascular Risk Indices in Apparently Healthy Individuals after 14 Days of Consumption of Costus afer Stem Extract

Ibiene Sarah Kalio, Okon, Abigail Effiong & Mina Josephine Iyama · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Costus afer has been used for both medicinal and nutritional purpose without adequate knowledge of its systemic effect. This study therefore, sought to determine the cardiovascular risk indices in fifteen (15) apparently healthy individuals aged between 20-35years after 14days of...

Open access Research Article 10.9734/jamps/2022/v24i530302

Use of Prazosin for Post-traumatic Stress Disorder in Adolescents is Associated with Longer Inpatient Psychiatric Hospitalization

Dina Khoury, Bao-Nhan Benjamin Nguyen, Laura Lai & David Safani · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: Prazosin has been shown to be effective in reducing PTSD-related nightmares in adolescents in outpatient studies with modest sample sizes. There are no data on the effects of prazosin on length of inpatient psychiatric hospitalization. Given prazosin’s adverse effects...

Open access Research Article 10.9734/jamps/2022/v24i530301

AmpC Beta-Lactamase Prevalence in Isolates of Escherichia coli and Klebsiella pneumoniae in Enugu, Nigeria

Uzoamaka Charity Maduakor, Immaculate C. Ajiromanus & Anulika Obianuju Onyemelukwe · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background: Pathogenic bacteria with beta lactamase-resistant determinants have emerged, posing a worldwide health threat. They confer resistance to a large array of \(\beta\) -lactam agents and \(\beta\)-lactam inhibitors. Aim: This study evaluated the prevalence and resistance...

Open access Research Article 10.9734/jamps/2022/v24i530300

Polyethylene Glycol Conjugation for Solubility Enhancement of Cefadroxil, a Poorly Soluble Antibiotic

B. Jeevana Jyothi, Y. Keerthana & N. Deekshita Reddy · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: Cefadroxil is the most widely used antibiotic for many bacterial infections but has the drawback of poorly solubility. In an attempt to provide an easier technique which can be scaled up on large scale to provide a simple method to enhance its aqueous solubility, th...

Open access Research Article 10.9734/jamps/2022/v24i530299

In vitro Antimitotic Activity and Molecular Docking Studies of Isolated Compounds from Rhynchosia beddomei

M. Lakshmi Madhuri & R. Raja Reddy · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The goal of this work was to use an exquisite combination of phytopharmacological and modern computational tools to examine the anticancer potential of Rhynchosia beddomei. The methanolic extract of Rhynchosia beddomei was screened for in vitro antimitotic activity like Allium ce...

Open access Research Article 10.9734/jamps/2022/v24i430297

COVID-19 and Obesity: The Collision of the Two Disasters

Roni Varghese Oommen, Shashank Gotarkar & Swarupa Chakole · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The first instances of COVID-19 were reported in late December in Wuhan, Hubei region, China. This virus is most commonly seen in mammals, most notably bats, camels, cows, and some kinds of pigs. Despite this, it is well recognised that viral transfer from animals to humans is ex...

Open access Research Article 10.9734/jamps/2022/v24i530298

Effects of the Anti-diabetic Polyherbal (Ruzu Bitters) on Glucose, Hepatic and Renal Parameters in Alloxan-induced Diabetic Rats

Ojoye N. Briggs, Kemzi N. Elechi-Amadi, Tarila N. Aleruchi-Didia, Eberechukwu O. Anyalebechi & Shammah Agwor · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: This study evaluated the effects of the anti-diabetic polyherbal (Ruzu Bitters) on glucose, hepatic and renal parameters in alloxan-induced diabetic rats. Methodology: A total of 35 male Albino rats weighing between 120-140 g were used for this study. Diabetes was induced by...

Open access Research Article 10.9734/jamps/2022/v24i430296

Curative and Toxic Effects of Selected Medicinal Plants on Internal Organs of Rattus albus Experimentally Infected with Human Intestinal Parasites

Immaculata O. Uduchi, Okolie Nnaemeka J. C., Ambrose U. Opara, Cajetan E. Ilo, Emmanuel Ifeanyi Obeagu & Samuel I. Ogenyi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Curative and Toxic effects of selected plant extracts: (Napleonaea imperalis, Sida acuta and Vernonia amygdalina) on Rattus albus experimentally infected with human intestinal parasites was studied from October 2014 to March 2016. Two hundred and thirty (230) male and female pati...

Open access Research Article 10.9734/jamps/2022/v24i430295

Alteration of Some Sperm Proteins, Anti-oxidants, and Prostate-specific Antigen in the Seminal Plasma of Bacteriospermic Infertile Males

Aminayanate M. Aworu, Ibioku Elekima, Adline Ben-Chioma, Holy Brown & Ebirien-Agana S. Bartimaeus · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: To investigate the alteration of some sperm proteins, anti-oxidants, and prostate-specific antigen in the seminal plasma of bacteriospermic infertile males. Study Design:  The study is a case-control design to investigate the semen parameters and some sperm proteins in infer...

Open access Research Article 10.9734/jamps/2022/v24i430294

Evaluation of Histopathological Effects of Smoked Marijuana on Albino Rats and Its Oxidative Stress Indices

Nnaemeka Okorie, Emmanuel Ifeanyi Obeagu, Mfon Ufot, Simon Onyema Azi, Ugonma Agwu Ude, Gideon Ama Ibiam, Christopher Okwu Ogbuanya, Innocent Chidi Jacob & Ewa Ibe Onyekachi · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Smoking marijuana (cannabis Savita), a psychoactive substance may result in side effect on living cells of the system and oxidative stress may meditate some of these effects. This study aims to evaluate the acute and chronic histopathological effect on wistar albino rat as well a...

Open access Research Article 10.9734/jamps/2022/v24i330293

Effective Inhibition of H5N1 Influenza Virus Infectivity using Safe and Calculated Low Power Generated from Life Restoration device under Different Conditions

Waleed Ezzat Madboly & Ahmed M. Abu-Dief · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: The use of the antiviral drugs and vaccination against pathogenic viruses induce some disorders and death cases. Therefore, it is urgent to develop an alternative therapy to protect and reduce the virus side effects. Here, in this report we designated a novel device t...

Open access Research Article 10.9734/jamps/2022/v24i330292

Acute and Sub-Acute Evaluations of Parsonsia straminea Stem Bark Ethanol Extract Impact on Some Behavioral Parameters in Mice

James Kemelayefa, Hope Kagbo & Udeme Georgewill · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: The plant Parsonsia straminea (P.S) have little or no ethnopharmacological records but local claims; as such its behavioral impact determination leads this study. The study team is poised at assessing the changes in behaviors such as: Motor coordination, anxiety, and...

Open access Research Article 10.9734/jamps/2022/v24i330291

Prevalence of Methicillin Resistant Staphylococcus aureus Infections among Hospitalized Wound Patients from Selected Tertiary Hospitals within Enugu Metropolis

Chidimma Maureen Chukwueze, Theophilus Kachi Udeani, Emmanuel Ifeanyi Obeagu, Justina Nwabunachi Ikpenwa & Asogwa Nneka · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

The incidence of Staphylococcus aureus infection especially in wound infections continues to rise. This study was aimed to evaluate the prevalence of methicillin resistant Staphylococcus aureus in hospitalized patients with wound infections in selected tertiary hospitals within E...

Open access Research Article 10.9734/jamps/2022/v24i330290