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All published articles 889

Acute and Sub-chronic Toxicological Studies of Citrus aurantium Fruit Juice in Wistar Rats

Obiajulu Christian Ezeigwe, Uchechukwu Chibuzo Ogbodo, Gift Nonso Okwuenu, Ezennaya Chidinma Felicia & Ifedilichukwu Nma Helen · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Citrus aurantium remains an excellent source of vitamins and phytochemicals. C. aurantium has been associated with lots of medicinal uses ranging from weight management to the treatment of nausea, cardiovascular diseases and cancer. This study therefore aimed at determining the a...

Open access Research Article 10.9734/jamps/2022/v24i330289

An Overview of FDA Approved Liposome Formulations for Cancer Therapy

Khushal Gajera & Adil Patel · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

One of the early achievements of researchers to develop Nano drug delivery systems were successfully manifested in the form of liposomes. Since the time of its invention in 1965, many technological advancements have been witnessed in Liposomal drug delivery systems, which are a f...

Open access Research Article 10.9734/jamps/2022/v24i330288

Knowledge and Use of Oral Rehydration Solution in the Management of Childhood Diarrhoea among Mothers in a Tertiary Health Facility in Port-Harcourt, Nigeria

C. Okechukwu, A. Alabi & LE. Yaguo-Ide · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: Oral rehydration solution (ORS) has been a life-saving remedy in the home and hospital management of dehydration, particularly in infants and children under the age of five. The improper use has however resulted in morbidity and mortality in children. The purpose of...

Open access Research Article 10.9734/jamps/2022/v24i230287

Hypoglycemic and Antihyperlipidemic Effects of Ethanolic Fruit Peel Extract of Carica papaya (pawpaw) in an Alloxan-induced Diabetic Rats

M. Haruna, Y. Abdulmumin, T. M. Abdulmumin, M. Murtala & M. M. Dalhatu · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Background:  Diabetes mellitus is a severe health concern that is usually linked to a person's lifestyle and genetic variables. Its frequency of occurrence is alarming. Anti- diabetics drugs are costly and come with adverse effects. This study aims to evaluate the phytochemical,...

Open access Research Article 10.9734/jamps/2022/v24i230285

Dexamethasone, Interleukin 6, and the Adrenal Gland are the Real Battles for COVID-19: Our Molecular Docking, Physiological, and Immunological Explanations of Why the Clinical Benefit of Dexamethasone is More Evident in Males

Amr Ahmed, Randa Mohamed M. A. Farag, Samar M. Hussein Algendy, Asmaa Houjak & Mahmoud Elkazzaz · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

More than two years have passed since the pandemic and despite all the efforts of researchers, the pathogenesis of the SARS-CoV-2 has not yet been resolved. The SARS-CoV-2 coronavirus that causes COVID-19 has high ability of mutation resulting in different variants of the virus....

Open access Research Article 10.9734/jamps/2022/v24i230284

Study of Cranial Capacity among Igbo Adolescents in Southeastern Nigeria

Ezeokoli Uzo Victory & Ukoha Ukoha · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

This work was aimed at comparing cranial capacity and multiple intelligence in Anambra adolescents. Three hundred and eighty three subjects were enlisted in the study, comprising 228 females (59.5%), and 155 males (40.5%), with an age range of 10-19 years. Each subject filled the...

Open access Research Article 10.9734/jamps/2022/v24i230283

Development of Questionnaire for the Assessment of Awareness about Heart Attack among Adults in Quetta Pakistan

Khizar Ali, Noman Ul Haq, Maria Fatima, Syed Mohkum Uddin, Muhammad Saood & Aqeel Nasim · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Objectives: Awareness of heart attack is very important to reduce the mortality and morbidity associated with a heart attack. The current study aims to develop a questionnaire to assess heart attack awareness among adults in Quetta, Pakistan, and also focused on translating into...

Open access Research Article 10.9734/jamps/2022/v24i230282

Factors Favoring the Toxic Effects of Metformin in Subjects with Type 2 Diabetes in Two Referral Hospital in Douala, Cameroon

Antoine Vayaraï Manaoda, Azinwi Ngumsi Fuh, Jacques Yinyang, Jean Pierre Nda Mefo’o, Jean pierre Ngene, Gisele Etame Loe & Dieudonné Adiogo · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introduction: The Metformin is a first line agent for the treatment of type 2 diabetes that can be used alone or in combination with sulfonylureas thiazolidinediones, incretin-based drugs, sodium/glucose cotransporter-2 inhibitors, or other hypoglycemic agents. Metformin is the m...

Open access Research Article 10.9734/jamps/2022/v24i130281

Role of Platelet Rich Plasma in the Treatment of Foot Ulcers: A Review

Shivani Kshirsagar, Chandrashekhar Mahakalkar, Anshu Agarwal, Meghali Kaple & Siddharth Mendiratta · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

An ulcer is a breach in the continuity of epithelium of mucous membrane and skin when an inflamed necrotic tissue sloughs out. Ulcers are caused by various medical conditions. The key to treatment is daily conventional dressing till the formation of healthy granulation tissue, in...

Open access Research Article 10.9734/jamps/2022/v24i130280

The Ameliorative Effect of Ginkgo biloba Supplement on Cyclosporine- A Induced Renal Toxicity in Male Wistar Rat

Uzoije Nnamdi Nwokoma, Lekpa Kingdom David, Henrrietta Ogadimma Asuzu-Samuel, Akoko Sokiprim & Precious Ojo Uahomo · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Ginkgo biloba supplement is a flavonoid-rich herbal supplement with several therapeutic potentials. However, the efficacy of Ginkgo biloba supplement to protect the kidney against cyclosporine-A induced renal toxicity is not fully understood. This study is to investigate the effe...

Open access Research Article 10.9734/jamps/2022/v24i130279

Variation in some Haematological Parameters in Patients with Plasmodiasis Attending Antenatal Clinic in Primary Health Care Centre, Ozuoba, Port Harcourt

B.E. Echonwere-Uwikor, O.E. Chukwuigwe-Igbere, P.H. Chukwu, F.K. Uwikor, T.N. Aleruchi-Didia & B. Gogo · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Introdction: Haematological parameters are useful in making diagnosis of diseases and also help in the antenatal assessment of women during pregnancy. The physiological changes of pregnancy, due to the influence of hormones such as oestrogen, progesterone also affect haematologic...

Open access Research Article 10.9734/jamps/2022/v24i130278

Assessment of Some Reproductive Hormones in Acute Lead-Acetate-Induced toxicity in Male and Female Albino Rats Treated Hypoestes rosea Leaf

F. K. Uwikor, B. E. Echonwere-Uwikor & O. E. Chukwuigwe-Igbere · Journal of Advances in Medical and Pharmaceutical Sciences · 2022

Aim: To assess the levels of some gonadal hormones in lead-acetate-induced Albino Rats treated with Hypoestes rosea Leaf. Study design: Experimental study. Place and Duration of Study: Department of Pharmacology, University of Port Harcourt and Department of Medical Laboratory Sc...

Open access Research Article 10.9734/jamps/2022/v24i130277

Chemical Composition, Antioxidative and Anti-Hyperglycemic Activity of Combined Seed Extracts of Xylopia aethiopica and Trichilia emetica in Alloxan Induced Diabetic Wistar Rats

A. Dokubo, Y. G. Nwidag & H. A. Orlu · Journal of Advances in Medical and Pharmaceutical Sciences · 2021

The chemical composition, in vivo antioxidative and antihyperglycemic activities of aqueous and ethanol seed extracts of combined Xylopia aethiopica and Trichilia emetica in a ratio of 1:1 mixture was studied in alloxan- induced diabetic wistar rats. Twenty-five wistar rats weigh...

Open access Research Article 10.9734/jamps/2021/v23i1230271

Relationship between Fasting Blood Sugar and Some Haematological Parameters in Diabetic Patients Attending Nigerian Navy Reference Hospital Calabar, Cross River State, Nigeria

C. Okpokam, Dorathy, E. Echonwere- Uwikor, Beauty, O. Opara, Chukwuka & O. Emeribe Anthony · Journal of Advances in Medical and Pharmaceutical Sciences · 2021

Background of Study: Diabetes mellitus is a clinical syndrome characterized by hyperglycemia due to absolute or relative deficiency of insulin. Lack of insulin, whether absolute or relative, affects the metabolism of carbohydrate, protein, fat, water and electrolytes (Sacks, 2013...

Open access Research Article 10.9734/jamps/2021/v23i1230273

Patients with Parathyroid Disorders: Oral Manifestations and Dental Management

Georges Aoun, Houssam Abou Hamdan & Pamela Aoun · Journal of Advances in Medical and Pharmaceutical Sciences · 2021

Parathyroid hormone secreted by the parathyroid glands has a key role in the regulation of calcium and phosphorus metabolism and plays an essential role in tooth and bone mineralization. Disorders of the parathyroid glands most frequently result in abnormalities of serum calcium...

Open access Research Article 10.9734/jamps/2021/v23i1230274