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All published articles 889

Genotoxic Effect of Arsenate and Arsenite in Human HaCat Cells in Culture Using Comet Assay

Ghazalla Benhusein, Elaine Mutch & Faith M. Williams · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Arsenic is an environmental chemical of toxicological concern today since it is a human genotoxin and chronic exposure is associated with development of cancers, including skin. Inorganic arsenate is metabolically reduced to arsenite by glutathione (GSH) prior to methylation. The...

Open access Research Article 10.9734/jamps/2020/v22i1230211

Ameliorative Effect of Nutmeg (Myristica fragrans) Supplement against Acetaminophen - Induced Hepato-Renal Toxicity in Wistar Rats

Chukwunyere Ogechi Abaekwume & Hope Delesi Kagbo · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: Recently, many drugs have been developed and used for the treatment of hepatic and renal diseases. Nutmeg apart from being utilized as kitchen spices in Nigeria has also been used for healing and medicinal purposes. Aims: In the present study, nutmeg supplement was ev...

Open access Research Article 10.9734/jamps/2020/v22i1130200

Physical Abuse in Its Extreme form Seen in a 12-Year-Old Female Adolescent

Ajaegbu Obinna, Okike Clifford Onuorah & Muoneke Uzoamaka Vivian · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: Child abuse occurs very frequently in Nigeria with approximately 6 out of every 10 children experiencing some form of violence. An estimate of 1 in every 4 girls and 1 in every 10 boys have undergone some form of sexual violence. Unfortunately this human violation oft...

Open access Research Article 10.9734/jamps/2020/v22i1130201

Intralipid in the Target Treatment of Lipid Peroxidation Disorder Caused by Oxidative and Nitro- Galogenic Stress in Patients with SARS-Cov2 / COVID / 19

Maria Vasilieva, Irina Vasilieva, Ilie Vasiliev, Stanislav Groppa, Gh. Ghidirim, Mircea Bețiu, Valentina Diug, Nicolae Bacinschi, Eugen Diug, Olga Tagadiuc, Pavel and Tanea Globa, Ninel Revenco, Gheorghe Plăcintă, Lorina Vudu, Jana Bernic, Gheorghe Caradja, Lilian and Elena Globa, Serghei Ignatenco, Ludmila Serbenco, Andrei Cealan, Mirta D'Ambra & Oleg Tarabrin · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: In the current proposal, we used the intralipid in standard therapy against COVID / 19 as an energy carrier for parenteral nutrition in critically ill patients. In patients receiving intralipid, there was an accelerated recovery of the lungs, a decrease in markers of...

Open access Research Article 10.9734/jamps/2020/v22i1130202

Assessment of Some Heavy Metals and Iron Parameters amongst Dumpsite Scavengers in Port Harcourt, Nigeria

A. S. Godwin, H. Brown & E. O. Nwachuku · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: The aim of the study was to determine the levels of some heavy metals, namely Cadmium (Cd), Lead (Pd), and Iron (Fe) in waste scavengers in port-Harcourt, Nigeria Study Design:  This study is a cross-sectional observational study. Place and Duration of Study: This study was...

Open access Research Article 10.9734/jamps/2020/v22i1130203

Assessment of Health Related Quality of Life among Chronic Kidney Disease Patients: Challenges for Nephrologists in Pakistan

Madeeha Malik, Iter Un Nisha & Azhar Hussain · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Introduction: During the past few decades, health related quality of life has been considered as an important predictor for positive health outcomes. Health-related quality of life assessment helps in determining the impact of disease on the everyday life of patients. Chronic kid...

Open access Research Article 10.9734/jamps/2020/v22i1130204

In vitro Antischistosomal Activity of Clerodendrum umbellatum Poir (Labiateae) Leaves Aqueous Extract and Derived Fractions against Schistosoma mansoni Adult Worms

Mérimé Christian Kenfack, Hermine Boukeng Jatsa, Nestor Gipwe Feussom, Emilienne Tienga Nkondo, Ulrich Membe Femoe, Christelle Dongmo Tsague, Etienne Dongo, Paul Désiré Djomeni Dzeufiet, Pierre Kamtchouing & Louis-Albert Tchuem Tchuente · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: Treatment against schistosomiasis relies on praziquantel. Its treatment failure and the possible development of resistant schistosomes strains have been reported in the literature. Clerodendrum umbellatum leaves are used in Africa for the treatment of intestinal helminthias...

Open access Research Article 10.9734/jamps/2020/v22i1030199

Patient Satisfaction with Colorectal Rapid Access Clinic

Kirsty Cattle, Thomas Athisayaraj, Neil Keeling & Ami Mishra · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aims: Patients referred with red flag colorectal cancer symptoms are seen within 2 weeks of referral and require completion of treatment within 62 days of referral.  The demand on resources is such that the remit of this rapid access pathway (RAP) is to diagnose or exclude cancer...

Open access Research Article 10.9734/jamps/2020/v22i1230205

Ethnopharmacological Study of Plants Used against Malaria by Traditional Healers in the Department of Bouna, North-Eastern Côte d'Ivoire

Koffi Akissi Jeanne, Tano Konan Dominique, Kangah Orphée Michelle Alerte, Rasmane Na Ahou Kaddy, Ehoulé Kroa, Dable Marius Trésor & Yavo William · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Mosquitoes have developed resistance, hence the need for anti-malarial medicines. This resistance calls for therapeutic an interest to therapeutic alternatives, including the medicinal plants. An ethnopharmacological survey was conducted amongst 15 Traditional Healers, recommende...

Open access Research Article 10.9734/jamps/2020/v22i1030196

Low Plasma Iron Levels Associated to Drug Treatment in Polymedicated Patients: A Case-Control Study

R. Lozano, A. Frutos, A. Apesteguía, A Martinez, M. E. Franco & M. A. Alcazar · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Aim: To identify the drug class and/or duration of treatments causing hyposideremia. Study Design: Retrospective case-control study. Place and Duration of Study: Departments of Internal Medicine and Pharmacy, Aragón Health Services Services Hospital Real de Nuestra Señora de Grac...

Open access Research Article 10.9734/jamps/2020/v22i1030197

Evaluation of Some Heavy Metals in Selected Sea Foods Directly from the Creeks in Rivers State, Nigeria

Ibioku Elekima, Raphael B. Edookue, Nengi F. Pepple, Aminayanate M. Aworu & Adline E. Ben- Chioma · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

To assess and compare the levels of arsenic, cadmium, mercury and lead, in common seafoods (mudskippers, periwinkle and Shrimp) consumed in Rivers state obtained from different creeks of Rivers State Nigeria. Study Design: Commonly consumed seafoods in Rivers State: Periopthalmus...

Open access Research Article 10.9734/jamps/2020/v22i1030198

Management of Advanced Stages of Chronic Kidney Disease Patients with the Administration of Renadyl Capsule: A Single Center Pilot Study in Bangladesh

Tanjina Rahman, Sampurna Guhathakurta, Akibul Islam Chowdhury, Fahmida Karim Munni, Harun Ur- Rashid, Shakib Arefin, M. Akhtaruzzaman & Mohammad Asadul Habib · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: Chronic kidney diseases become a public health concern as the rate of this diseases is increasing. Thus, the aim of the study was to evaluate the changes in key biomarkers in Bangladeshi CKD stages IV and V patients by using Renadyl capsule. Study Design: Open label r...

Open access Research Article 10.9734/jamps/2020/v22i1030195

Assessment of Some Biochemical Changes in Wistar Rats Following Administration of Three Polyherbal Preparations Repurposed for COVID-19

Kennedy Iliya Amagon, Bukata Bayero Bukar, Jacob Adegboyega Kolawole, Kakjing Dadul Falang, Ukpe Ajima, James Garba Damen, Yusuf Amuda Agabi, Richard Joseph Kutshik, Ishaya Yohanna Longdet, Simji Samuel Gomerep, Ismaila Shittu, Stephen Daniel Davou & Noel Nen’man Wannang · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background and Aims: The current pandemic known as Coronavirus Disease-19 (COVID-19) is a significant public health menace. Currently, there is no specific treatment for this disease, although some medicinal agents are under investigation. Some published articles have reported Se...

Open access Research Article 10.9734/jamps/2020/v22i930194

Perception and Acceptance of the Doctor of Medical Laboratory Science (MLSD) Degree (A Professional Doctorate Degree) among Medical Laboratory Scientists in Nigeria

Kemzi N. Elechi- Amadi, Ojoye N. Briggs, Valerie E. Ugochi, Obeta M. Uchejeso & Abdulsalam Yakubu · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

Background: The practice of Medical Laboratory Science has witnessed advancement globally, with increasing need for laboratory input in modern healthcare delivery. This has brought about the need for advanced education and training for practitioners of Medical Laboratory Science....

Open access Research Article 10.9734/jamps/2020/v22i930193

Pharmacovigilance in Cameroon: Past, Present and Future Developments in Unlocking the Drug Development Process

Estella Achick Tembe Fokunang, Bruna Njeba, Marie Jose Essi, Rose Ngono Abondo, Banin Andrew Nyuki, Lovet Benyella Fokunang, Nubia Kaba, Marie-Thérèse Abena Ondoua, Ralf Duerr & Charles Ntungwen Fokunang · Journal of Advances in Medical and Pharmaceutical Sciences · 2020

The drug discovery and development processes are designed to guarantee that drugs are efficacious, nontoxic and of high standards of quality for human consumption. However, patient’s population with access to drugs at approval is only a fraction of the final target population. Th...

Open access Research Article 10.9734/jamps/2020/v22i930192