Aims: The study was aimed at comparative evaluation of body weight changes and the serum growth hormone level in female lactating Wistar rats treated with normal saline, metoclopramide olanzapine and risperidone. Study Design: A total of twenty (20) Female Wistar rats weighing be...
Open access
Research Article10.9734/JAMPS/2018/43977
Aim: The aim of this work was to increase the bioavailability of linagliptin, a BCS class-III drug, by improving permeability. For this purpose, linagliptin loaded different non-ionic surfactant vesicles were formulated and evaluated using statistical optimization. Methods: Two i...
Open access
Research Article10.9734/JAMPS/2018/44198
Androgenic alopecia is the common type of non-scarring hair loss affecting the scalp in both males and females with genetic pre-determined. Platelet-rich plasma is a preparation of platelets in concentrated plasma. This method is applied for treating different types of alopecia....
Open access
Research Article10.9734/JAMPS/2018/41994
Aims: The study aimed to identify the socio-demographic factors and reasons for parental self-medication of hospitalised children under 15 years. Materials and Methods: The present study was carried out in Departments of Pediatry (Sylvanus Olympio and Campus Teaching Hospitals) o...
Open access
Research Article10.9734/JAMPS/2018/44016
Aims: The aim of this investigation is to study the effect of virgin coconut oil on the prefrontal cortex upon aluminium chloride-induced Alzheimer- likes dementia. Study Design and Methodology: Twenty-eight (28) adult male Wistar rats were used and were randomly assigned into fo...
Open access
Research Article10.9734/JAMPS/2018/35221
Background: Despite the success of anti-retroviral drugs, renal impairment remains one of the most significant complications of HIV. This study aimed to evaluate the prevalence of renal impairment and its association with age, gender, CD4 and TNF alpha of HIV positives in the Uni...
Open access
Research Article10.9734/JAMPS/2018/40957
Introduction and Aim: The know-how of local antibiograms is very important in the light of continuous changes in resistance patterns in different geographical niches. This retrospective observational study assessed the in vitro susceptibility pattern of pathogen isolates from dif...
Open access
Research Article10.9734/JAMPS/2018/44300
Background: Surgical site infections (SSIs) are one of the most frequent complications associated with surgeries and contribute significantly to morbidity and mortality if not treated promptly. Poor prognosis associated with SSIs could be partly attributed to the increase in ant...
Open access
Research Article10.9734/JAMPS/2018/41647
Amelogenesis imperfecta (AI) - a hereditary heterogenous disorder causing developmental alterations in the structure of enamel. The Al trait can be transmitted by either autosomal dominant, autosomal recessive, or X-linked modes of inheritance. Genes implicated in autosomal forms...
Open access
Research Article10.9734/JAMPS/2018/39759
Objective: To analyze cerebrospinal fluid (CSF) in acute bacterial and viral meningitis patients and differentiating between bacterial and viral meningitis upon the changes observed in CSF compositions. Methodology: This was a hospital based study conducted from June 2016 to Nove...
Open access
Research Article10.9734/JAMPS/2018/43406
Aim: The study was aimed to identify etiology of bacteria associated with wound infections and antimicrobial susceptibility profile of the isolated organisms in the community. Study Design and Methodology: It is a retrospective study; data was obtained from Medical Microbiology d...
Open access
Research Article10.9734/JAMPS/2018/41845
Aims: This study aims to comparatively investigate the effects of Cimetidine, Ascorbic acid (Vit C), Citrus aurantifolia and Tetracarpidium conophorium on male fertility hormones in adult male albino Wistar rats. Study Design: 96 Albino rats randomly assigned into 6 groups (A –...
Open access
Research Article10.9734/JAMPS/2018/42992
M. E. Kooffreh, A. J. Umoyen, E. V. Ikpeme, O. U. Udensi, E. E. Ekerette, O. M. Etukudo, E. Okon, E. Eze, N. Ephraim, S. O. Abraham, N. M. Effiong, M. O. Ozoje & R. Duke·Journal of Advances in Medical and Pharmaceutical Sciences·2018
Background: Primary open-angle glaucoma is one of the commonest causes of blindness due to optic nerves damage because of elevated intraocular pressure and it is the commonest form of glaucoma. We determined the frequency of CYP1B1 gene mutations spectrum among families with open...
Open access
Research Article10.9734/JAMPS/2018/41763
Background: Benign Prostate hyperplasia (BPH) is a highly prevalent disease among older men and a substantial public health problem. We investigated leaf extract of Ocimum gratissimum (OG) effect on lipid prolife in BPH. Methods: BPH was induced in male rats weighing 200-300g thr...
Open access
Research Article10.9734/JAMPS/2018/43113
Background & Aim: Emphysematous pyelonephritis (EPN) is an acute necrotizing infection of upper urinary tract characterized by the presence of gas in renal parenchyma and peri-renal tissue. We report a case of diabetes mellitus with renal calculi who was diagnosed with EPN du...
Open access
Research Article10.9734/JAMPS/2018/42703