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All published articles 889

Knowledge, Attitude, Perception and Behaviour of Patients towards Drug Leaflet in Riyadh, Saudi Arabia

O. A. Alkhamees, N. A. Qureshi, M. A. Al Fadhel & S. M. Alsanad · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: Patient-tested and -friendly information leaflets provide sufficient, accurate, and pertinent information about prescribed and over-the-counter medications to health consumers for their safety, enhanced satisfaction, improved outcomes and no medication errors across t...

Open access Research Article 10.9734/JAMPS/2018/41493

Evaluation of Vigna subterranea seed Extract as Possible Adjuvant for Typhoid Fever Vaccine

Ifeoma Agatha Onah, Chinedu Ofojebe & Damian Chukwu Odimegwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Typhoid fever is an essential communicable disease that is endemic in developing countries characterised by poor water supply, sanitary conditions and increasing population. Vaccination with the Salmonella typhi (ST) vaccine is an effective control measure. The two currently lice...

Open access Research Article 10.9734/JAMPS/2018/41329

Effect of Strophanthus hispidus Dc. (Apocynaceae) Roots Extract on Normal and Hyperglycemic Rats

Akinlami O. Omokehinde, Adegoke O. Temidayo, Ibukunoluwa M. Rebecca, Famobuwa E. Olaniyi & A. Oyebade · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Objective: To investigate the hypoglycemic activity of both ethanol extract Strophanthus hispidus root (EESHR) and chloroform extract Strophanthus hispidus root (CESHR) respectively. Methods: Both ethanol extract Strophanthus. hispidus root and chloroform extract Strophanthus. hi...

Open access Research Article 10.9734/JAMPS/2018/40393

Comparative Study of Cardiopulmonary Functions in Trained Male Athletes and Singers– A Pilot Study

O. O. Omodara, P. P. Mshelia, A. A. Madaki & M. I. A. Saleh · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Objectives: Studies have shown that both physical exercise and singing have beneficial medical effects on the cardiopulmonary functions of humans in health and disease conditions, but it is not yet known whether physical exercise or singing is more effective in producing these be...

Open access Research Article 10.9734/JAMPS/2018/40220

Antityrosinase Activities of Thespesia populnea Bark and Phyllanthus emblica Fruit

H. K. I. Perera, A. P. C. Pradeep, K. D. U. Devinda, R. M. U. K. Ratnayake, D. K. L. R. Gunawardhana & J. A. V. P. Jayasinghe · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: Currently there is enormous demand for skin-lightening agents, creating a quest for identification of new substances. Tyrosinase has become the main drug target for reducing skin pigmentation. The objective of this study was to detect tyrosinase inhibitory effects of eight...

Open access Research Article 10.9734/JAMPS/2018/40775

Theoretical Investigation of Correlations Between Molecular and Electronic Structure and Antifungal Activity in Coumarin Derivatives: Combining Qsar and Dft Studies

Abduljelil Ajala, Adamu Uzairu, Idris O. Suleiman & Ahmed Jibrin Uttu · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Quantitative structure-activity relationship (QSAR) models were combined with density functional computations and used to predict anti-fungi activities in a series of coumarin derivatives. Essential descriptors employed in this study were chosen based on the use of the Genetic Fu...

Open access Research Article 10.9734/JAMPS/2018/22801

In Silico Analysis for DPYD Gene and the Effect of the Mutation on Dihydropyrimidine Dehydrogenase Enzyme

Asia M. Elrashid, Mohamed Y. Basher, Ali I. A. Gharib, Mohamed A. I. Alfaki, Nawarz M. Mohammed, Ahmed M. Elmoselhy, Sahar G. Elbager & Safinaz I. Khalil · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: The aim of this study was to implement an in silico bioinformatics analysis for clinically observed missense variants in human DPYD gene to investigate the effect these variants on Dihydropyrimidine dehydrogenase enzyme 's structure and function. Methods: The human DPYD gene...

Open access Research Article 10.9734/JAMPS/2018/40300

Effect of an Angiotensin Converting Enzyme Inhibitor (Captopril) on Liver and Kidney Function Parameters in Plasmodium berghei-Infected Mice

R. K. Bala, A. M. Abdulazeez, A. I. Kiru, N. S. Abdullahi & B. A. Abubakar · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aim: This study was carried out to investigate the effect of captopril on serum liver enzymes (AST, ALT, and ALP), total serum protein and kidney function parameters such as electrolytes (HCO3-,  Cl-, Na+, and K+), urea and creatinine in Plasmodium berghei-infected mice. Methodol...

Open access Research Article 10.9734/JAMPS/2018/40599

C-reactive Protein, Trace Element and Lipid Profile in Cardiovascular Disease

Olooto E. Wasiu, Amballi A. Adetola, A. Aiyedun, Onayemi A. Adedeji & Olawale O. Oladipupo · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: The increase in consumption of industrial processed food, economic instability consequent to global economic recession; job losses; increase incidence of diabetes and chronic kidney disease; increase steroids use; dyslipidemia; and obesity has been implicated in the g...

Open access Research Article 10.9734/JAMPS/2018/40194

Renal and Metabolic Effects of Goutweed (Aegopodium podagraria L.) Extract Compared with Potassium Chloride in Rats Receiving Hydrochlorothiazide

O. V. Tovchiga & S. Yu. Shtrygol · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: To determine the influence of Aegopodium podagraria L. aerial part extract on the function of the kidney and the metabolic processes in rats receiving hydrochlorothiazide (HCTZ, 80 mg/kg). Study Design:  The  rats  were  randomly  distributed  to five groups: Group  I:  int...

Open access Research Article 10.9734/JAMPS/2018/40313

Phytochemical Screening and Antibacterial Activity of Cynodon dactylon Extracts against Escherichia coli

Shakira Nakitende, Ibrahim Ntulume & Julius Tibyangye · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: To determine the phytochemical constituents and antibacterial potential of Cynodon dactylon leaf extracts against Escherichia coli. Study Design: Experimental short-term prospective study. Place and Duration of Study: The study was conducted in Kampala International Univers...

Open access Research Article 10.9734/JAMPS/2018/39990

Evaluation of Cytotoxicity and Antibacterial Activities of Methanolic Extract of Antidesma bunius (Linn.) (Family Euphorbiaceae) Leaf

Sonia Zaman, Md. Shariful Islam, Sabiha Ferdowsy Koly, Tahmid Faisal & Kamruzzaman Rakib · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: The aim of this study was to find out the cytotoxicity and antibacterial activity of the methanolic extract of leaf of Antidesma bunius (Family Euphorbiaceae). Place and Duration of Study: The study was carried out in August 2017 in the Department of Pharmacy, Southeast Uni...

Open access Research Article 10.9734/JAMPS/2018/40004

Determinants of Malaria Treatment Seeking Behaviour among Urban and Rural Households in North Central Nigeria

Paul Otor Onah · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

  Background: Malaria is a major cause of morbidity and mortality in Nigeria accounting for a significant proportion of household expenditure in treatment and prophylaxis. Nigeria account for 25% of global clinical cases and mortality and also has the highest malaria burden in su...

Open access Research Article 10.9734/JAMPS/2018/31413

Changes in White Blood Cells Differential Associated with Adult Malaria-Infected Patients

J. C. Ozougwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: Malaria parasites are expected to impact the white blood cell differential of malaria patients, but reports on changes in white blood cell differentials of malaria patients are not well documented, hence this study was undertaken to determine changes in white blood cell dif...

Open access Research Article 10.9734/JAMPS/2018/38784

Monitoring of Renin-angiotensin-aldosterone-system (RAAS) Inhibitors and Diuretics Applied in General Hospital-Ikot Ekpene and St. Luke’s Hospital-Uyo of Akwa Ibom State, Nigeria

Eshiet, Unyime Israel & Jackson, Idongesit Linus · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: Blockade of renin-angiotensin-aldosterone system (RAAS) has been shown to be beneficial in patients with hypertension, acute myocardial infarction, chronic heart failure and diabetic renal disease. However, RAAS inhibitors and diuretic therapy are associated with so...

Open access Research Article 10.9734/JAMPS/2018/39209