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All published articles 889

Availability, Accessibility and Affordability of Antimalarial Drugs in Benue State, North Central Nigeria

Paul Otor Onah · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Title: Availability, accessibility and affordability of antimalarial drugs in North Central Nigeria Objectives: To assess the availability and affordability of antimalarial drugs in healthcare facilities as well as compare prices and affordability within and between sectors. Back...

Open access Research Article 10.9734/JAMPS/2018/32292

Reversibility Capacity of Aqueous Extract of Moringa oleifera Leaf on Cyclophosphamide Induced Immunotoxicity in Male Wistar Rats

S. O. Ojeka, D. V. Dapper & A. A. Okerengwo · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: Cyclophosphamide is a chemotherapeutic alkylating drug currently used in combination with other protective agents for the purpose of reducing the adverse toxic effects. Increasingly, plants have become sources of therapeutics that can help to restore host immunity t...

Open access Research Article 10.9734/JAMPS/2018/38319

Knowledge, Attitude and Compliance with Safety Protective Measures and Devices among Commercial Motorcyclists in Sokoto Metropolis, Northwestern Nigeria

Nasiru Lawal, M. O. Oche, B. A. Isah, A. Yakubu & M. O. Raji · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Background: Motorcycle accidents occur frequently in this part of the world as a result of interface among the agent, the host and its environment resulting in fatal consequences. The objective of this study was to assess the Knowledge of, attitude and compliance with road safety...

Open access Research Article 10.9734/JAMPS/2018/39205

In vitro Free Radical Scavenging and Antioxidant Activities of Aqueous Extracts of Crateva adansonii (Three-leaf Plant)

H. C. C. Maduka, C. E. Ugwu, C. C. Dike, A. N. Okpogba, P. N. Ogueche, M. S. Ali, S. S. Bakare & J. Tino · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Ethnopharmacological Relevance: Crateva adansonii popularly known as Three-Leaf plant is used in some South Eastern part of Nigeria by traditional medicine practitioners to treat certain diseases such as infertility and infection. Aim: This research work aimed at investigating th...

Open access Research Article 10.9734/JAMPS/2017/38321

In vitro Antimycobacterial Screening of Ficus sycomorus Extracts on Susceptible Strain of Mycobacterium tuberculosis

M. A. Song, M. M. Abarshi, D. A. Ameh, M. S. Aliyu, K. Mamuda, E. Nicolas, A. Isiyaku, P. Meshak, I. Mosunmola, K. Abba & S. Mikailu · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Aims: To evaluate the Anti-mycobacterial activity of Ficus sycomorus extracts by in vitro screening against susceptible strain of Mycobacterium tuberculosis to standard TB drugs. Study Design: Hospital/University based cross sectional study. Place and Duration of Study: National...

Open access Research Article 10.9734/JAMPS/2017/38201

Hygroscopic Expansion Influence on Cuspal Deflection of Tooth Composite Restoration

Hossam M. Mossa, Essam I. Elkhatat & Labib M. Labib · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: Polymerization shrinkage can result in gap formation between the composite material and tooth structure with subsequent plaque accumulation, which affect the esthetic quality of a restoration and initiate periodontal diseases. Aim: The aim of this study was to evalu...

Open access Research Article 10.9734/JAMPS/2017/38834

The Correlation of Promoter Polymorphism and Expression of Androgen Receptor Gene with Hypospadia Incidence

Yevri Zulfiqar, Yanwirasti ., Jamsari . & Irfan Wahyudi · Journal of Advances in Medical and Pharmaceutical Sciences · 2018

Introduction: Hypospadia is one of the most common congenital abnormalities, yet the exact cause remains unknown. Androgen Receptor (AR) is suspected to cause hypospadias. Methods: As many as 49 post-operative prepuces of hypospadia patients and 49 normal prepuces from elective c...

Open access Research Article 10.9734/JAMPS/2017/34294

The Disintegrant Property of a Hydrophilic Cellulose Polymer Derived from the Tubers of Ipomoea batatas in Paracetamol Tablet Formulation

Ugoeze Kenneth C. & Nwachukwu Nkemakolam · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: A new hydrophilic cellulose polymer (I-hydrocel) derived from the tubers of Ipomoea batatas was assessed as a tablet disintegrant in paracetamol tablet formulation in comparison with maize starch. Methods: I-hydrocel was incorporated intragranularly at 5, 10 and 15% w/w to...

Open access Research Article 10.9734/JAMPS/2017/37119

Oxygen Saturation Status and Prevalence of Respiratory Symptoms among Female Bakery Workers Using Fossil Fuel in Benin-City, Nigeria

J. N. Oko-Ose · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Flour dust is a respiratory sensitizer and chronic exposure to it and to Carbon Monoxide as a result of burning fossil fuel could affect the pulmonary functions and stimulate allergic responses. This study is designed to determine occupational related respiratory symp...

Open access Research Article 10.9734/JAMPS/2017/37903

Routine Histopathological Analysis of Non-suspicious Looking Foreskin for Adult Patients: Is It Necessary?

N. Kadi, L. Kayali & A. S. Bates · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Objective: To evaluate the routine histopathological analysis of foreskin in adult patients and determine whether histological processing is necessary in patients with non-suspicious foreskin.  Materials and Methods: All adult foreskin sent for histopathological analysis between...

Open access Research Article 10.9734/JAMPS/2017/38117

Berberine Prevents Bone and Cartilage Destruction and Influences Cell Senescence in Experimental Arthritis

Petya Ganova, Lyudmila Belenska-Todorova, Tsvetelina Doncheva & Nina Ivanovska · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Berberine (BB) is a protoberberine alkaloid with a wide spectrum of pharmacological activities considered to be a selective Janus kinase (Jak)3 inhibitor. Nevertheless, the mechanisms of berberine’s actions on joint inflammation have not been well clarified. Aim: This...

Open access Research Article 10.9734/JAMPS/2017/37839

In vitro Comparison of Metronidazole and Tinidazole Activity against Trichomonas vaginalis Strains in Maiduguri, Nigeria

H. S. Hamafyelto, I. E. Ikeh & O. V. Oladele · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This study investigated the in vitro comparison of metronidazole and tinidazole activity against Trichomonas vaginalis strains from internally displaced women in Maiduguri, Nigeria. Materials and Methodology: high vaginal swab samples were collected from (41) T. vaginalis positiv...

Open access Research Article 10.9734/JAMPS/2017/36205

Effects of Citrus Limon Juice on Serum Bilirubin, High Density Lipoprotein and Low Density Lipoprotein in Adult Male Wistar Rats under Variable Models of Stress

Anachuna Kenneth Kelechi, Daubry Tarela Melish Elias, Ewhre Oberhiri Lawrence & Oyem John Chukwuma · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Introduction: There has been sufficient awareness on atherosclerosis but this has not reduced the number of people with it. Atherosclerosis is promoted by low density lipoprotein (LDL) without sufficient removal of fats and cholesterol by high density lipoprotein (HDL). Stress is...

Open access Research Article 10.9734/JAMPS/2017/37768

Assessment of Total Serum Immunoglobulin E and Eosinophilic Cationic Protein in Primary Mono-symptomatic Nocturnal Enuresis: Allergic Theory?

Hanan M. Hamed, Amany M. Abd Al-Aziz, Ayat A. Motawie, Amany A. A. Fatouh & Mona A. M. Awad · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Introduction: The available evidences indicate that nocturnal enuresis has multi-factorial etiology and this may underlie the wide range of outcomes. Various pathophysiological mechanisms have been discussed and succeeded in defining many causes of enuresis such as disturbed func...

Open access Research Article 10.9734/JAMPS/2017/37732

Evaluation of the Suspending Properties of a Novel Hydrophilic Biopolymer Derived from the Tubers of Ipomoea batatas on Sulphamethoxazole Suspension

Ugoeze Kenneth C. & Nwachukwu Nkemakolam · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: This work examines a novel hydrophilic biopolymer, I-polygel derived from Ipomoea batatas tubers (Convolvulaceae) as a suspending agent in sulphamethoxazole suspension using acacia and tragacanth respectively as comparing standards. Methods: Aqueous suspensions of sulphamet...

Open access Research Article 10.9734/JAMPS/2017/37028