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All published articles 889

Antibacterial Activity of Three Cameroonian Medicinal Plants Traditionally Used for the Treatment of Urinary Tract Infections and Their Synergistic Effects with Amoxicillin and Serum

Jean-de-Dieu Tamokou, Jules-Arnaud Mboutchom Fosso, Abdel Jélil Njouendou, Steve Endeguele Ekom & Irene Chinda Kengne · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Urinary tract infections (UTIs) are the second most common form of infectious diseases that affect humans after respiratory diseases. It is predicted that 20% of the adult female population is exposed to development of an UTI. The emergence of UTIs is promoted by the...

Open access Research Article 10.9734/JAMPS/2017/37419

Antiplasmodial Potential of Combination Therapy of Methanolic Bark Extracts of Terminalia avicennioides and Anogeissus leiocarpus and Its Effect on Haematological Parameters on Mice Infected with Plasmodium berghei

O. M. Akanbi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: The resistance of Plasmodium species to drugs has necessitated the search for more potent drugs. Anogeissus leiocarpus and Terminalia avicennioides have been considered traditionally for the treatment of malaria. Aim: This study assessed the efficacy of combination th...

Open access Research Article 10.9734/JAMPS/2017/35105

Phytochemical Screening, Spectrophotometric Determination of Total Carotenoids, Chlorophyll a and b Components of Crateva adansonii (Three-leaf Plant)

H. C. C. Maduka, A. A. Maduka, C. U. Aguoru, B. K. Myke-Mbata, J. O. Ikwue, A. N. Okpogba, C. E. Ugwu, C. C. Dike, P. N. Ogueche, D. O. Ochalefu, Nath Ufaryna, J. Yakubu & E. Shatar · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To screen Crateva adansonii phytochemically for phytosterol, phenol, proteins, amino acids, and to determine the pigment levels in Crateva adansonii using various types of solvents. Study Design: This study was designed to determne the pigment levels in the extracts of diff...

Open access Research Article 10.9734/JAMPS/2017/30052

Vitamin D and Parathyroid Hormone Levels and Their Relation to Serum Ferritin Levels in Children with Thalassemia Major: One-Center Study in Western Indonesia

Amirah Zatil Izzah, Zelly Dia Rofinda & Firman Arbi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Children with thalassemia major need regular blood transfusions to survive. These multiple transfusions put them at risk for iron overload, which result in organ damage such as parathyroid gland. The aim of this study is to determine levels of calcium, phosphorus, vit...

Open access Research Article 10.9734/JAMPS/2017/35473

Compositions of Thunbergia grandiflora Leaf and Root Essential Oils

Kingsley Adibe Mbachu & Dorcas Olufunke Moronkola · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Fresh samples of leaves and roots of Thunbergia grandiflora were collected from forest- reserved area, Ibadan, Nigeria for extraction of their volatile oils. Hydro-distillation method was used in an all-glass Clevenger apparatus designed to British pharmacopeia specifications. It...

Open access Research Article 10.9734/JAMPS/2017/35836

Knowledge Level and Perceptions of Pharmacists and Prescribers Regarding Boxed Warnings

Michael L. Adams, Wesley D. Rich & Valerie B. Clinard · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Black box warnings indicating harmful or potentially fatal adverse events are required by the Food and Drug Administration on certain drugs and chemical entities; however it is unclear if prescribing and dispensing habits are impacted by these warnings. This study inv...

Open access Research Article 10.9734/JAMPS/2017/36666

Evaluation of the Activity of Lippia alba Leave Extract in Reducing Ochratoxin A in Albino Rats

Olukayode Olugbenga Orole, Timothy Olubisi Adejumo & Japhet Erasmus Aisoni · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Ochratoxin A is a metabolite of fungal origin with the potential of inciting oxidative stress which results in disease conditions in man and animals. Plant parts from time immemorial have been used to treat disease conditions with considerable success, hence the study is aimed at...

Open access Research Article 10.9734/JAMPS/2017/35875

Knowledge, Attitude and Practice towards Antibiotics Use among Non-medical University Students in Uyo, Nigeria

Ifunanya Evangeline Asogwa, Samuel James Offor & Herbert Orji Chidi Mbagwu · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: The widespread use, misuse and overuse of antibiotics in human and veterinary medicine have resulted in emergence and spread of antibiotics resistance consequently decreasing their effectiveness and efficacy. Recent studies consistently reveal that university students...

Open access Research Article 10.9734/JAMPS/2017/35671

Effect of Ethanolic Leaf Extract of Sarcocephalus latifolius on Some Biochemical Parameters in Alloxan Induced Diabetic Rats

M. N. Ndukwe, G. I. Adoga & C. D. Luka · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This research project was carried out to investigate the biochemical effect of Sarcocephalus latifolius leaf extract in alloxan induced diabetic rats. The study was carried out for about 12 months in the department of Biochemistry University of Jos, Jos, Nigeria and Prestige medi...

Open access Research Article 10.9734/JAMPS/2017/34311

Intramedullary Interlocking Nailing for Long Bone Fractures of the Lower Limbs: Our Experience with Free-hand Locking

Shamsuddeen Muhammad & Abdurrahman Alhaji Mamuda · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To see the pattern of interlocking nailing used for fractures of lower limb’s long bones in terms of the bone affected, laterality, age distribution, sex distribution, pattern of locking and early outcome. Study Design: The study is a retrospective cross sectional study con...

Open access Research Article 10.9734/JAMPS/2017/35079

Rat Serum Electrolytes and Lipid Profiles Following Administration of Aqueous Extract of Sphenostylis stenocarpa

Okoye Ngozi Franca & Dimkpa Precious Isioma · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: Aqueous extract of the seed of African yam bean (Sphenostylis stenocarpa) is used in Nigerian alternative medicine for the treatment of high blood pressure. Therefore the aim of this study is to investigate the effect of Sphenostylis stenocarpa seed extract on some electroly...

Open access Research Article 10.9734/JAMPS/2017/34369

The Frequency of CYP3A5 Expression in a Mexican Population Compared to a Caucasian Population

Jason W. Guy, Arthur F. Harralson, Kylie Pooler & Robert S. Kidd · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To determine the frequencies of the six most common CYP3A5 alleles and genotypes in a Mexican-American population compared to a non-Hispanic Caucasian population.  Study Design: This cross-sectional study compared the frequency of CYP3A5 genetic variations in a Mexican-Amer...

Open access Research Article 10.9734/JAMPS/2017/35168

The Phytochemical and Antimicrobial Potentials of the Crude Extracts of Bridelia ferruginea and the Extracellular Biosynthesized Silver Nanoparticles

Temitayo Omotola Akinsete, Bukola Christianah Adebayo-Tayo & Abimbola Olumide Adekanmbi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Bridelia ferruginea has been used in African folk medicine for the treatment of several ailments especially throat infections. In this study, the phytochemical analysis, fractioning using different solvents, antimicrobials and silver nanoparticles (SNPs) produced by the ethanolic...

Open access Research Article 10.9734/JAMPS/2017/34172

The Use of Modular Distal Aiming Device (MODAD) System for Locked Intra-medullary Nailing for Fixation of Fractures in Nigeria: A Prospective Observational Study

S. E. B. Ibeanusi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Locked intra medullary nailing has been accepted globally as the gold standard for treating fractures of the shaft of long bones. The method provides acceptable stabilisation of the fracture, controls alignment, axial translation and rotational deformity at the fracture. The chal...

Open access Research Article 10.9734/JAMPS/2017/34680