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All published articles 889

Pattern of Adverse Drug Reaction to Antiepileptic Drugs at a Tertiary Hospital in North-Central Nigeria: A Prospective Observational Study

Emeka U. Ejeliogu & Aderonke Uhunmwangho-Courage · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Epilepsy is a common neurologic condition affecting 0.5-1% of the popula­tion. Adverse drug reactions (ADRs) are a major health problem to the individual as well as for the society. There is insufficient awareness and inadequate training on drug safety monitoring amon...

Open access Research Article 10.9734/JAMPS/2017/35337

End-of-life Care in Nigeria: Preparing Nursing Students and Workforce to Take the Lead

Peretomode Evans & Udo Eunice · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

In this 21st century, several factors have informed the increasing need of end-of-life care globally. Notable amongst them are the global changes in both demographic and disease pattern; factors that have led to increasing number of chronic illnesses. Individuals suffering from c...

Open access Research Article 10.9734/JAMPS/2017/34876

Do Iron Chelators Affect Fertility in Thalassemic Men?

Shahla Ansari, Azadeh Kiumarsi, Azita Azarkeivan, Mohammad Mahdi Allameh, Maryam Razzaghy-Azar & Davoud Amirkashani · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Iron overload is a major complication in patients with thalassemia, however, development of iron-chelating therapy has partly overcome this problem. Objectives: The aim of this study was to evaluate the effect of iron chelator drugs on testicular volume, semen paramet...

Open access Research Article 10.9734/JAMPS/2017/33728

Saponin Fraction of Gongronema latifolium Reverses Dyslipidemia and Catalyzes Glucokinase in Lowering Blood Glucose Sugar in Streptozocin-Induced Diabetic Rats

G. O. Igile, I. A. Iwara, O. O. Ekpe, B. I. A. Mgbeje & M. U. Eteng · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Objective: Gongronema latifolium (GL) is a bitter tasting leaf used in Nigeria as spice in food, and as herb for the treatment of diabetes, malaria and cardiovascular disease. Research work on the anti-diabetic activities of the whole leaf extract has been carried out, but none o...

Open access Research Article 10.9734/JAMPS/2017/34310

Quality Control Tests for Ophthalmic Pharmaceuticals: Pharmacopoeial Standards and Specifications

Md. Sahab Uddin, Abdullah Al Mamun, Md. Tanvir Kabir, Jinnat Ruksana Setu, Sonia Zaman, Yesmin Begum & Md. Shah Amran · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

The therapeutically performance of the pharmaceuticals must be constant and expectable.  In order to claim a pharmaceutical to be a quality drug, it must fulfill certain standards and specifications. The quality of pharmaceuticals is strongly related to the patient’s well-being....

Open access Research Article 10.9734/JAMPS/2017/33924

In vivo-Study of Antiviral Effect of Gossypium hirsutum Extract on Newcastle Disease Virus

G. Ezeifeka, P. Nwiyi, U. Effiong, I. Ukwueni, I. Erumaka, A. Onyeabor, I. O. Oguoma & N. Amaechi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Gossypium hirsutum belongs to the family Malvaceae and genus Gossypium, the name of the genus is derived from the Arabic word goz, which refers to a soft substance. This plant occupies a very important position in traditional medicine because of its ethnomedicinal value. The aim...

Open access Research Article 10.9734/JAMPS/2017/34530

Leveraging on Prompt Proactive and Preventive Integrated Strategies (PPPIS) for Meningitis Control in Nigeria: Getting it Right

O. Ogbonna Brian · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Given the escalating morbidity and mortality recorded annually due to meningitis outbreak in Nigeria, it is fast becoming a disease of public health concern. Objectives: This study described and discussed preventive strategies based on the disease pattern to generate...

Open access Research Article 10.9734/JAMPS/2017/34507

The Relationship between Selected Anthropometric Indices and Cardiorespiratory Fitness in Apparently Healthy Young Adults in a Nigerian Community

C. N. Ofiaeli, A. V. Egwuonwu, M. J. Nwankwo, Y. E. Ihegihu & U. P. Okonkwo · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background and Aim: Cardiorespiratory fitness (CRF) is a useful tool for establishment of baseline fitness status and monitoring of physical activity level. Therefore, it may by extension serve as health risk index. However, studies that have determined the correlation between an...

Open access Research Article 10.9734/JAMPS/2017/33677

Evaluation of the Victims of Road Traffic Crashes Presenting in Hospitals in the Federal Capital Territory Abuja, Nigeria. A Prospective Pilot Study

Sydney E. Ibeanusi & Tom Sough · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Road Traffic Crashes are indeed major contributor of disability and death globally. Accurate and reliable data on actual number of victims of road traffic crashes in various countries is required to understand the burden of road traffic crashes and to implement interv...

Open access Research Article 10.9734/JAMPS/2017/34331

Effect of Curcumin on Blood Glucose Level and Some Neurobehavioral Responses in Alloxan-induced Diabetic Swiss Albino Mice

U. A. Garkuwa, A. W. Alhassan & Y. Tanko · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

The aim of this study was to evaluate the effect of curcumin on blood glucose level and neurobehavioral response in Alloxan-induced diabetic Swiss Albino mice. The animals were divided into five (5) groups of four each (n=4). Group I served as control and received distilled water...

Open access Research Article 10.9734/JAMPS/2017/34323

Antibacterial and Antioxidant Activities of Dacryodes edulis Methanolic Leaf Extract

Olasunkanmi Oluwaseun Oyetunji & Adeniyi Paul Opeyemi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

  Dacryodes edulis is used for the treatment of several ailments such as malaria, oral and ear infection. This study was designed to determine the antibacterial and antioxidant potentials of Dacryodes edulis methanolic leaf extract as well as its rate of killing on some selected...

Open access Research Article 10.9734/JAMPS/2017/33831

Haematological Profile and Some Reproductive Indices of Male Albino Rats Treated with Ethanolic Stem Bark Extract of Picralima nitida

E. C. Mbegbu, R. I. Odo, D. C. Edeh & I. R. Obidike · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: To evaluate the effects of graded doses of ethanolic stem bark extract of Picralima nitida on haematological profile, some serum reproductive hormones, sperm reserves and testicular histomorphology of male albino rats. Study Design: Thirty male albino rats, weighing between...

Open access Research Article 10.9734/JAMPS/2017/34359

Evaluation of Nitrate Reductase Assay for Detection of Multi-drug Resistant Mycobacterium tuberculosis among Patients at National Tuberculosis Reference Laboratory Zaria Nigeria

K. Mamuda, O. S. Olonitola, E. D. Jatau & E. Nicholas · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To evaluate nitrate reductase assay for detection of multi-drug resistant Mycobacterium tuberculosis among patients at National Tuberculosis Reference Laboratory Zaria Nigeria. Study Design: Hospital based cross sectional study Place and Duration of Study: National Tubercul...

Open access Research Article 10.9734/JAMPS/2017/33705

Protein Syntheses in Epithelial-mesenchyme Transitions as Markers of Platelet-induced Cultured Cancer Cell Proliferation

Brian J. Poindexter, Lenard M. Lichtenberger, Dexing Fang & Roger J. Bick · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To study the changes in protein content and protein patterns in platelet activated epithelial-mesenchymal transition of cultured colon cancer cells. Place and Duration of Study: UT McGovern Medical School, Houston, Texas, USA. Between May, 2015 and May, 2017. Methodology: M...

Open access Research Article 10.9734/JAMPS/2017/34071

Susceptibility Patterns of Staphylococcus aureus Isolated from Wounds Swabs to Extracts of Vernonia amygdalina

O. Oluyele & M. K. Oladunmoye · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: There is an ever growing interest in investigating different groups of plants to identify their potential therapeutic applications. This is due to a tremendous historical legacy in folk medicine use of plants as remedy for treating diseases. Vernonia amygdalina have been sh...

Open access Research Article 10.9734/JAMPS/2017/33837