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All published articles 889

Biochemical Assessment of Parkia biglobosa Ethanolic Root Extract in Streptozotocin Induced Diabetic Rats

R. U. Ukpanukpong, R. N. Uyabeme, I. A. Adekunle & C. O. Adeleke · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: To investigate the antidiabetic effect of Parkia biglobosa ethanolic root extract in streptozotocin induced diabetic rats. Place and Duration of Study: Department of Biochemistry, College of Natural Sciences, Joseph Ayo Babalola University, Ikeji Arakeji Osun State, Nigeria,...

Open access Research Article 10.9734/JAMPS/2017/24877

Evaluation of Efficacy of Co-artemisinin in the Treatment of Plasmodium falciparum Malaria in Gombe State, Nigeria

M. D. Hassan, M. M. Dauda, Y. Mohammed, B. Muhammad, A. A. Kudi, S. C. Muhammad, M. M. Manga & A. Umar · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: To evaluate the potency and efficacy of co-artemisinin brands used in the treatment of uncomplicated Plasmodium falciparum malaria in Gombe State North-Eastern Nigeria. Materials and Methods: A total of 185 patients with malaria aged between 5-60 years attending Federal Teac...

Open access Research Article 10.9734/JAMPS/2017/32303

Antibacterial Activity and Phytochemical Screening of Mangifera indica (Mango) Stem and Leaf Extracts on Clinical Isolates of Methicillin Resistant Staphylococcus aureus

S. U. Diso, M. Ali, S. I. Mukhtar & M. Garba · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Medicinal plants have been sources of a number of important compounds which have been discovered during last century. In the light of their established therapeutic efficacy, the pharmaceutical industries are using crude extracts of medicinal plants for manufacturing d...

Open access Research Article 10.9734/JAMPS/2017/31127

Rationale of Polyunsaturated Fatty Acids Supplementation in the Frame of the Magnocellular Theory of Dyslexia

Carlo Aleci · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

In the last decades evidence has been collected that the depletion of the visual magnocellular population (a fast-conduction cellular system made of large ganglion neurons) plays a pathogenetical role in developmental dyslexia. Smaller size of the magnocells and reduction of thei...

Open access Research Article 10.9734/JAMPS/2017/32962

Potential 5-Fluorouracil Encapsulated mPEG-Chitosan Nanogels for Controlling Drug Release

Dai Hai Nguyen · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: The objective of this study was to prepare and characterize poly (ethylene glycol) methyl ether (mPEG)-conjugated chitosan (CS) nanogels, mPEG-CS, at different molar ratios for 5-Fluorouracil (5-FU) delivery (5-FU-loaded mPEG-CS nanogels). Study Design: The chemical cross-l...

Open access Research Article 10.9734/JAMPS/2017/32493

Antimicrobial Potential of Extracts of Hyptis suaveolens (L) Poit. Leaves on Some Gram Positive Bacterial Isolates

Ojo Omolara Comfort & Giwa Holy Johnson · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This study investigated the antibacterial potential of the methanolic extract and other different fractions obtained from the crude extract of Hyptis suaveolens leaves on some selected Gram positive bacterial isolates. It also assessed the antibiotic susceptibility patterns of th...

Open access Research Article 10.9734/JAMPS/2017/32562

Bioassay-guided Isolation of Antidermatophytic Compounds from Piper longum L.

Jayshree Das, Dhruva Kumar Jha, Jagannath Biswakarma, Rudragoud S. Policegoudra, Afjal Hussain Mazumder & Mrinmoy Das · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: Piper longum, a medicinal plant, grows wildly in Northeast India. In our earlier study, the chloroform extract from leaves of P. longum L. (Piperaceae) exhibited promising in vitro antidermatophytic activity. The present investigation was undertaken to isolate and identify...

Open access Research Article 10.9734/JAMPS/2017/31874

Hepatoprotective Effect of Aqueous Bark Extract of Bosweillia dalzielii against Paracetamol Induced Hepatotoxicity in Rabbits

A. M. Sa’id, M. S. Ibrahim, J. A. Mashi & I. U. Daha · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: This study assessed the hepatoprotective potential of aqueous stem bark extract of Boswellia dalzielii on paracetamol-induced hepatotoxicity in adult rabbits. Study Design:  Fifteen adult rabbits weighing between 1.4-2.0 kg were divided into five groups (I, II, III, IV and V...

Open access Research Article 10.9734/JAMPS/2017/31357

Role and Effectiveness of Simulation-based Training in Raising Family Medicine Residents’ Clinical Resuscitation and Critical Care Skills

Majid Kh. Al Harthi, Raouf M. Afifi, Mohamed A. Tashkandi, Ashraf E. Saad & ‎Yousef Afifi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Background: Family medicine (FM) physicians are bound to providing healthcare services at a variety of clinical and community settings. They should be equipped to competently handle health emergencies in a multitude of professional procedures. Medical education on patients often...

Open access Research Article 10.9734/JAMPS/2017/32234

Comparative Analysis of Antihistamines and Nonsteroidal Anti-inflammatory Drugs (NSAIDs): Properties, Structure and Prediction of New Potential Drugs

Ronald Bartzatt · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: To determine the molecular properties of common antihistamines and non-steroidal anti-inflammatory agents (NSAIDs). To identify interrelationships among these two groups of drugs utilizing pattern recognition methods and statistical analysis. Study Design: After determinati...

Open access Research Article 10.9734/JAMPS/2017/32695

In utero Exposure to Oxcarbazepine Causes Congenital Anomalies in Albino Rat Fetuses

Hamida Hamdi, Abd El Wahab El Ghareeb, Asmaa M. Kandil, Osama M. Ahmed & Rania Yahia · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: Oxcarbazepine (OXC) is a newer antiepileptic agent that has recently become increasingly used either as monotherapy or as an adjunct to other AEDs in adults, adolescents, and children with partial epilepsy. Our aim was to define the the potential risks of the anti-epileptic...

Open access Research Article 10.9734/JAMPS/2017/32345

Formulation of Natural Polymeric Nanoparticles to Overcome Barriers for the Treatment of Osteoporosis

Jayanthi . & Shymala Bhaskaran · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aims: The present paper focuses on natural polymeric nanoparticles (NPs), described in the literature as the most effective natural polymer that have been introduced in the last decades, We have recently developed an innovative approach to this aim: a new osteotropic biomaterial...

Open access Research Article 10.9734/JAMPS/2017/32428

In-vitro Antibacterial Activity and Phytochemical Screening of Psidium guajava on Some Enteric Bacterial Isolates of Public Health Importance

M. Ali, A. Yahaya, A. U. Zage & Z. M. Yusuf · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Aim: The study was conducted to investigate the antibacterial activity of Psidium guajava and its major antibacterial constituents (Phytochemicals). Materials and Methods: The aqueous and ethanol extracts from the leaves and stem bark of the plant was tested using well diffusion...

Open access Research Article 10.9734/JAMPS/2017/31126

Evaluation of CNS Depressant, Antidiarrheal and Antipyretic Activities of Ethanolic Leaf Extract of Calophyllum inophyllum L. on Swiss Albino Mice

Seuly Akter, Md. Saddam Hossain, Md. Rubel Mia & Md. Shahid Sarwar · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

Objective: The main objective of the present study was to evaluate the CNS depressant, antidiarrheal and antipyretic activities of ethanolic leaf extract of Calophyllum inophyllum L. Methods: In the present study CNS depressant activity of C. inophyllum was carried out using hole...

Open access Research Article 10.9734/JAMPS/2017/29994

Biochemical Effects of Telfairia occidentalis Leaf Extracts against Copper-induced Oxidative Stress and Histopathological Abnormalities

C. U. Ogunka-Nnoka, R. Amagbe, B. A. Amadi & P. U. Amadi · Journal of Advances in Medical and Pharmaceutical Sciences · 2017

This study was carried out to investigate the protective effect of oral administration of T. occidentalis against copper induced oxidative stress. Forty two adult male Wistar rats were divided equally into six groups. Group 1 were orally gavaged with standard animal feed only, gr...

Open access Research Article 10.9734/JAMPS/2017/31295