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All published articles 889

The Practice of Antibiotic Prophylaxis for Caesarean Delivery among Obtetricians and Trainee Obstetricians in Nigeria

A. E. Ogbe, A. S. Anzaku, I. G. Ogbu & B. O. Okwaraoha · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: Antibiotic prophylaxis is a recognized measure for preventing post-operative infection after Caesarean delivery and it is expedient that Obstetricians be aware and practice recommended regimen. This study aimed at ascertaining the knowledge and practice of antibiotic prophy...

Open access Research Article 10.9734/JAMPS/2016/30084

Synthesis of Unstable Vaterite Polymorph of Hollow Calcium Carbonate Nanoparticles and Encapsulation of the Anticancer Drug Cisplatin

S. P. Dunuweera & R. M. G. Rajapakse · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Cisplatin is the first generation platinum coordination complex-based anticancer drug developed to treat many different types of cancers. However, cisplatin is associated with numerous side effects. Most of these side effects could be minimized if cisplatin can be encapsulated in...

Open access Research Article 10.9734/JAMPS/2016/29784

Effects of Aqueous and Ethanolic Extracts of Entandrophragma angolense, Cola nitida and Gomphrena celosioides against Doxorubicin-induced Cardiotoxicity in Rats

Bamba Abou, F. Yapi Houphouet, Bahi Gnogbo Alexis, Djyh Bernard Nazaire, Djoupoh Agnon Prisca & Gnahoue Goueh · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: The present study was undertaken with an aim of evaluating the capacity of the aqueous and ethanolic extracts of Entandrophragma angolense, Cola nitida and Gomphrena celosioides to protect the heart of rats. Study Design: Cardioprotective properties of plant extracts in viv...

Open access Research Article 10.9734/JAMPS/2016/29269

Nutritive Composition and Antimicrobial Activity of Moringa stenopetala (Baker f.) Cufod

H. L. Raghavendra, T. R. Prashith Kekuda, B. N. Vijayananda, Dereje Duressa & Tifsehit Solomon · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: The present study was carried out to determine nutritive composition and to screen antimicrobial activity of leaf extract of Moringa stenopetala (Baker f.) Cufod. Place and Duration of the Study: The study was performed at Wollega University, Ethiopia, BGK Life Technologies...

Open access Research Article 10.9734/JAMPS/2016/29987

Induction of Heme Oxygenase-1 Improves Glucose Tolerance and Enhances Insulin Sensitivity in Obese Diabetic Rats

Adel H. Saad, Hanaa M. Ibrahim, Walaa H. Nazmy & Azza Hussein · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: Obesity is a worldwide problem. It is considered to be a major risk factor for many systemic diseases like type 2 diabetes mellitus (T2D), cardiovascular, renal and orthopedic diseases. Recent evidence has underscored the emerging role of the heme oxygenase system in many d...

Open access Research Article 10.9734/JAMPS/2016/29700

Nutritional Factors Associated with Breast Cancer in Gaza Strip - Palestine: A Hospital Based Study

Jehad H. El-Hissi, Dayana M. El-Batrokh, Ihab M. Al-Masri, Mazen A. El-Sakka & Adham I. Ahmed · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: To reveal the relationship between nutritional factors and dietary behavior and the occurrence of breast cancer in Gaza Strip. Materials and Methods: A retrospective case-control study that consisted of 150 participants, conducted in Al-shifa hospital at Gaza Strip. A seven-...

Open access Research Article 10.9734/JAMPS/2016/24778

Current and Future Strategies for AD Therapy

Agbo John, Omale O. Francis, Hassan D. Mhya & Awodele Olufunsho · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Alzheimer’s disease is an insidious disease of the brain. It is a degenerative and intractable neurological disorder that causes deterioration of memory, judgment, and reasoning in the elderly. About 46.8 million people worldwide are suffering from AD; prevalence is expected to a...

Open access Research Article 10.9734/JAMPS/2016/28271

Development of a Novel, Rapid and Validated HPTLC Protocol for the Quantitative Estimation of Marrubiin from the Extract of Marrubium vulgare Linn

A. Nanda & V. Mittal · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: To develop a novel, simple, precise and rapid HPTLC protocol for the analysis of marrubiin (a furan labdane diterpene) in herbal extracts and formulations. Methodology: The marrubiin can be quantified by performing the HPTLC on silica gel F254 plates using toluene: ethyl ace...

Open access Research Article 10.9734/JAMPS/2016/29840

Trypanostatic Effect of Millet-garlic Blended Diet on Rats Infected with T. b. brucei

M. H. Garba, A. Y. Kabir, A. Abubakar, A. Abdul Qadir, Y. Garba, F. M. Madaki, L. M. Hafsa & S. Abubakar · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: The nutraceutic effect of millet-garlic blend against trypanosomiasis in Trypanosoma brucei brucei challenged rats was investigated in this study. Experimental Design: The experimental rats were grouped into A, B, C, D, E, F, G, H, I, and J in a complete randomised clinical...

Open access Research Article 10.9734/JAMPS/2016/26318

Evaluation of the Effectiveness of Telfairia occidentalis Leave Extracts in the Amelioration of Carbon Tetrachloride Induced Liver Injuries and Oxidative Damage in Rats

Abiodun Olusoji Owoade, Abiodun Bukunmi Aborisade, Adewale Adetutu & Olubukola Sinbad Olurunnisola · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: The study was aimed to investigate the efficacy of Telfairia occidentalis (T. occidentalis) extracts in the attenuation of CCl4-mediated oxidative stress. Place and Duration of Study: Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomosho, Nigeria,...

Open access Research Article 10.9734/JAMPS/2016/29199

Effects of a Hydro-ethanolic Extract of Scoparia dulcis on Systemic Inflammation and Cachexia in an Allergic Asthma Model

Jones Ofori-Amoah, George Asumeng Koffuor, Felix Amissah, George Owusu, Aaron Opoku Antwi & Verner Ndudiri Orish · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Chronic allergic lung diseases, such as allergic asthma, are often marked by increased systemic inflammatory responses and cachexia co-morbidities. Objectives: The study aimed at evaluating the systemic anti-inflammatory and anti-cachectic properties of a hydro-ethano...

Open access Research Article 10.9734/JAMPS/2016/29032

Oxytocin Hormone Administration Attenuates Cardiac Oxidative Injury and Inflammation in Hypercholesterolemic Rats

Walaa `Hassan Nazmy, Hanaa M. Ibrahim, Adel Hussein Saad & Alaa El Din R. Abdel Rheim · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: Oxytocin (OT) hormone has been recently recognized as a cardiovascular hormone with diverse regulatory roles. The present study examined the potential protective effect of exogenous OT administration on hypercholesterolemia-induced injury in rat heart and possible mechanism...

Open access Research Article 10.9734/JAMPS/2016/28932

Effects of Acetylsalicylic Acid and Salicylic Acid on the Growth of HeLa Cervical Cancer Cells Line

Ibrahim Mohammed, Mohammed Ozovehe Musa & Abdu Umar · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Introduction: Cervical cancer is the fourth most common cancer affecting women in the world, 527,000 new cases were reported and over 250,000 deaths were reported each year. The major risk factor of cervical cancer is infection with HPV. The aim of our research is to determine th...

Open access Research Article 10.9734/JAMPS/2016/29034

Prescribing Errors in Nigeria’s Healthcare System; Exploration towards Promoting Rational Prescribing for Improved Patient Care

O. Ogbonna Brian · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Rational prescribing is vital to achieving rational drug use but limited studies exist on the prescription practices, causes, and types of prescription error in developing countries. Prescription error is one of the leading causes of morbidity and mortality globally. However, due...

Open access Research Article 10.9734/JAMPS/2016/26864

Iatrogenic Baclofen Neurotoxicity in End Stage Renal Disease: A Case Report and Review of Literature

Navaneedha Lingam Mahalingam & Rizna Abdul Cader · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Baclofen is a centrally acting antispasmodic agent that is commonly prescribed to patients suffering from spinal cord problems. Nearly 85% of baclofen is excreted by the kidneys whereas the remaining 15% is metabolized by the liver. In patients with renal insufficiency, baclofen...

Open access Research Article 10.9734/JAMPS/2016/29261