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All published articles 889

In vitro Analysis of the Interaction between Ketorolac Tromethamine and Bovine Serum Albumin Using Fluorescence Spectroscopy

Kanij Nahar Deepa, Md. Zakir Sultan, Md. Shah Amran & Shaila Kabir · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objectives: To evaluate the in vitro mutual interaction of ketorolac tromethamine with bovine serum albumin (BSA) using fluorescence spectroscopy under different conditions. Materials and Methods: Different concentrations of ketorolac were mixed with 20 µM bovine serum albumin so...

Open access Research Article 10.9734/JAMPS/2016/29006

Molecular Insights into the Role of Inflammation and Oxidative Stress in Epilepsy

Shah Nigar, Faheem Hyder Pottoo, Nahida Tabassum, Santosh Kumar Verma & Md. Noushad Javed · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Epilepsy is a chronic neurological disorder manifested as unpredictable, unprovoked recurrent seizures that affect a variety of mental and physical functions. Despite the use of current anti-epileptic drugs (AEDs) about 30% of patients remain refractory, while 30-40% have associa...

Open access Research Article 10.9734/JAMPS/2016/24441

Comprehensive Patients’ Self-reported Causes of Non-compliance to Antihypertensive Medications in Maiduguri, Nigeria

John David Ohieku & Jabir Said Suleiman · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Many strategies have been employed to improve compliances to antihypertensive medications but these efforts are not translated into good compliances with several patients leading to high cases of morbidity and mortality. The study probes into the medication compliance...

Open access Research Article 10.9734/JAMPS/2016/28484

Comparison of Two Standardizations Used in Antibiotic Susceptibility Testing in Helicobacter pylori

Simone Ulrich Picoli, Bruna Rafaella Becker, Luiz Edmundo Mazzoleni, Erli Neuhauss & João Carlos Prolla · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Helicobacter pylori is a bacterium that is widespread in the world's population and constitutes a risk factor for the development of gastric cancer. One possible cause of treatment failure is antimicrobial resistance, indicating the importance of susceptibility testing. Aims: The...

Open access Research Article 10.9734/JAMPS/2016/28658

Proactive Nursing Care is the Key to Successful Day Case Laparoscopic Cholecystectomy at a Rural Hospital

Aemelia Melloy, Ria De Rouw & Arkadiusz Peter Wysocki · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: Day case laparoscopic cholecystectomy is achievable but in most hospitals it is not routine. We describe our experience with day case laparoscopic cholecystectomy in a rural Queensland hospital. Methods: Retrospective analysis of consecutive adult patients with uncomplicated...

Open access Research Article 10.9734/JAMPS/2016/29117

Chemical Evaluation, Free Radical Scavenging Activities and Antimicrobial Evaluation of the Methanolic Extracts of Corn Silk (Zea mays)

Stella A. Emmanuel, Olutayo Olajide, Salisu Abubakar, Saheed O. Akiode & Godwin Etuk-Udo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Corn silk is thought to possess medicinal properties according to Nigerian folklore. This study was undertaken to appraise its phytochemical constituents and anti-microbial activities. Data obtained revealed that alkaloids, flavonoids, tannins, saponins, steroids, glycosides and...

Open access Research Article 10.9734/JAMPS/2016/28530

The Impact of Age in Prosthesis-patient Mismatch on Long-term Survival after Aortic Valve Replacement: in-vitro versus in-vivo Values

Alexander Manché, Aaron A. Casha & Liberato Camilleri · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: We studied the effect of age on survival in the setting of prosthesis-patient mismatch (PPM). Study Design: Retrospective single surgeon practice. Place and Duration of Study: Cardiothoracic department, Mater Dei Hospital Malta, between January 1995 and December 2014. Method...

Open access Research Article 10.9734/JAMPS/2016/28381

Urinary Tract Infections in Adult Women: Review

Sundus Fadhil Hantoosh, Ibtisam Jasim Sodani & Dheaa Sh. Zageer · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Urinary tract infections occur more frequently in women than in men. Escherichia coli and Staphylococcus saprophyticus are the most common causatives of urinary tract infections in women. The severity of urinary tract infection is determined   by the innate defense mechanisms of...

Open access Research Article 10.9734/JAMPS/2016/28241

Beyond Drugs in Eliminating Malaria Scourge in Nigeria; Scaling-up Vector Control Strategies

B. O. Ogbonna, C. E. Ejim, G. N. Ele, I. G. Ohiaeri, L. N. Ezenekwe, C. N. Nwako & O. N. Ilonzo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Integrated vector control management strategy plays a pivotal role and occupies a vantage position today in World Health Organizations (WHO) road map to malaria elimination and Nigeria has the highest malaria burden in Sub-Saharan Africa. So much attention and huge financial and...

Open access Research Article 10.9734/JAMPS/2016/28057

Factors Affecting Radioprotective Efficacy of Ocimum sanctum (Tulsi) Extract in Mice

Mrinalini Tiwari, Rajan Murugan, Rajkumar Tulsawani, Vikram Gota, Rajiv K. Sarin, P. Uma Devi, Rajnedra P. Tripathi, Thangaraj Parimelazhagan, Bilikere S. Dwarakanath & Paban K. Agrawala · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Oscimum sanctum (Tulsi) is well reported for its medicinal values in Ayurveda. Although several chemical radioprotectors have shown excellent protection under in vitro conditions, lack of acceptable efficacy under in vivo conditions and/or undesirable toxicity has lim...

Open access Research Article 10.9734/JAMPS/2016/28152

Development of Combined Genetic and Imaging Approaches for Differentiation of Cutaneous Malignant Melanoma and Benign Melanocytic Nevi

S. Abdalla & N. Al-Aama · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

The morbidity and mortality rate is reduced by premature and exact diagnosis of melanoma, which is the deadliest type of skin cancer. Timely identification of melanoma needs extremely complex and subjective test and laboratory samples. It is not insignificant even for experienced...

Open access Research Article 10.9734/JAMPS/2016/28336

Evaluation of the Benefits, Quality of Services and Challenges to the Nigerian National Health Insurance Scheme among Enrollees in a Tertiary Teaching Hospital in Southeast Nigeria

G. N. Ele, U. Ochu, V. U. Odili, R. C. Okechukwu & B. O. Ogbonna · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objective: Access to quality healthcare has been a prerogative of the middle and high socioeconomic class leading to the introduction of health insurance in developing countries to share the burden, reduce cost, and step up health care financing and coverage. This study assessed...

Open access Research Article 10.9734/JAMPS/2016/28320

Comparative Studies on the Effects of Zidovudine, Nevirapine, Lamivudine and Bioclean II on Female HIV/AIDS Cases in Nigeria

I. N. Ibeh, M. A. Okungbowa, N. I. Ibeh & B. I. Adejumo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Definite cure for HIV/AIDS is not yet documented and over 40 million people in the world are believed to be infected with the virus. The present study evaluates the effects of Zidovudine + Lamivudine + Nevirapine (HAART) and Bioclean II on female HIV/AIDS cases in Nigeria. Candid...

Open access Research Article 10.9734/JAMPS/2016/16569

Adverse Haematological Changes in Plasmodium Infected Mice Following Treatment with Azadirachta indica (Neem) Leaf Extract

Itemobong S. Ekaidem & Henry D. Akpan · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Azadirachta indica (neem) is an effective natural remedy for malaria treatment in some tropical regions of Africa. This study investigated the impact of Azadirachta indica leaf-extract on some haematological indices of Plasmodium berghei-berghei infected mice. Materal...

Open access Research Article 10.9734/JAMPS/2016/28089

Anxiolytic Effect of Aqueous Root Extract of Citrus aurantium in Wistar Albino Rats

Muhammad Bawa Yusuf, Balaraba Bello & I. J. Jaafaru · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Anxiety is a very common mental disorder among neurological disorders. Citrus aurantium decoction has been used to treat anxiety- like behaviour, by traditional medicine practitioners in Nasarawa State, Nigeria. The aim of this study was to evaluate the effect of aqueous root ext...

Open access Research Article 10.9734/JAMPS/2016/27022