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All published articles 889

Preliminary Investigation of the Subchronic Hypolipidemic Actions of Hibiscus sabdariffa in Rats

Patrick Emeka Aba, Amarachi Ossai & Ernest Chukwuamachago Nweze · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Hibiscus sabdariffa is a popular medicinal plant that is claimed to have hypotensive and hypocholesterolemic actions in animals. The present preliminary study was conducted to assess the subchronic hypolipidemic actions of H. sabdariffa calyx in normal rats when administered as a...

Open access Research Article 10.9734/JAMPS/2016/23186

Isolated Jejunal Transection at Two Place in Blunt Trauma Abdomen – A Rare Case

Dinesh Kumar Barolia, Varu Lal Damor, Shameem Ahmad, Deepak Sethi, Devendra Atal & Balveer Singh · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Blunt trauma abdomen leads to varieties of injury to the intraperitoneal organ. Isolated small bowel injury is rare entity in blunt trauma abdomen. Complete transection of jejunum at two places is also a rare presentation in blunt trauma abdomen. Most of the reported cases of sma...

Open access Research Article 10.9734/JAMPS/2016/24707

Multidrug Resistant Salmonella enterica Strains in South Western Nigeria: Prevalence and Susceptibility to Ceftriaxone

P. A. Idowu, O. T. Jemiseye & T. S. Agidigbi · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: To investigate the prevalence and susceptibility pattern Salmonella enterica strains to ceftriaxone in southwestern Nigeria. Place and Duration of Study: Faculty of Pharmacy, University of Ibadan, Nigeria from November 2012-May 2013. Methodology: Isolates of Salmonella ente...

Open access Research Article 10.9734/JAMPS/2016/23533

Hemodialysis-associated Oxidative Stress: Comparison of Helixone® and Polysulfone® Dialyzer

Mourad Errasfa, Fatima Zahra Batta, Kaoutar Alaoui Sekkouri, Chakib Maaroufi, Mohamed Arrayhani & Tarik Sqalli Houssaini · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Patients at end stage renal failure require hemodialysis, a process that contributes to oxidative stress, where the quality of hemodialysis membrane plays a key role. Aim of the Study: We sought to investigate the effect of two different hemodialysis membranes (Helixo...

Open access Research Article 10.9734/JAMPS/2016/24141

Micronucleus as a Non-invasive Biomarker – A Review

Manpreet Singh Dev, Sonal Grover, Jatinder Batra, Rohan Talathi, Manoj Jaiswal & Roopa S. Patil · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Oral Cancer has a remarkably high incidence worldwide and a significant decrease in its mortality and morbidity rates has been established if it is diagnosed in early stages. There has been always a strong need to develop new, objective, non-invasive methods for its early detecti...

Open access Research Article 10.9734/JAMPS/2016/24136

Cardiotoxic Assessment of Radiographic Developer Effluent in Wistar Rats

A. C. Ugwu, U. Dimkpa, D. Fotso, A. N. Eteudo, S. O. Maduka, N. N. Njoku-Oji, L. C. Anikeh & R. C. Uchefuna · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: To demonstrate the histopathological changes in cardiac tissues of Wistar rats following exposure to developer effluent. Study Design: A case control study. Place and Duration of Study: Department of Radiography, Nnamdi Azikiwe University, Nnewi Campus, Anambra State, Niger...

Open access Research Article 10.9734/JAMPS/2016/23330

Four Compounds Suppressing Growth of Mycobacterium tuberculosis

Ronald Bartzatt, Preeti Sule, Woojung Kim & Jeffrey D. Cirillo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: To demonstrate the efficacy of several small molecular weight compounds having hydrazide groups, for inhibiting the growth of Mycobacterium tuberculosis. To show these same compounds have favorable drug-likeness properties.  Study Design: To synthesize tuberculostats and te...

Open access Research Article 10.9734/JAMPS/2016/24351

Cysteine Protease Inhibitors from Calotropis procera with Antiplasmodial Potential in Mice

Abdullahi Abdulkadir, Ismail Alhaji Umar, Sani Ibrahim, Elewechi Onyike & Adamu Yusuf Kabiru · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Inhibitory activity of crude extract of cysteine protease inhibitors from Calotropis procera against Plasmodium berghei infected mice was investigated. Various extracts obtained from the leaves, roots, flowers, latex and stem bark of Calotropis procera using different extraction...

Open access Research Article 10.9734/JAMPS/2016/22866

Prevalence and Clinicoradiological Profiles of Respiratory Dysfunction in Patients with Medullary Infarction: Retrospective Case Study and Review of Literature

Masahiro Sawada, Takanori Takazawa, Ken Miura, Tetsuhito Kiyozuka & Ken Ikeda · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Respiratory dysfunction occurs in stroke patients. Little is known about the prevalence, clinical features and lesion topography in patients with dyspnea due to medullary infarction (MI). We aimed to evaluate the frequency and the clinicoradiological profile in dyspni...

Open access Research Article 10.9734/JAMPS/2016/24206

Acute Toxicity and Hypoglycemic Activity of Aqueous Fruit Pulp Extract of Adansonia digitata L. (Afpead) on Alloxan Induced Diabetic Rats

I. U. Muhammad, I. K. Jarumi, A. J. Alhassan, A. M. Wudil & M. A. Dangambo · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Oral LD50 and hypoglycemic activity of aqueous fruit pulp extract of Adansonia digitata L. (AFPEAD) were investigated in this research. A total of fourty eight (48) rats were used, twelve (12) of the rats were used for oral LD50 determination, and were grouped into four (4) group...

Open access Research Article 10.9734/JAMPS/2016/23862

Influence of Active and Passive Smoking on the Urinary Concentration of 1 Hydroxyl Pyrene, Oxidative Stress and Renal Activity in Male Subjects

H. K. Okafor, S. E. Omogo & Y. A. Omoniyi · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Objective: The purpose of the study was to investigate the influence of active and passive smoking on the urinary concentration of 1 hydroxyl pyrene, oxidative stress and renal activity in male subjects. Methods: Urine samples each of forty active and passive smokers including fo...

Open access Research Article 10.9734/JAMPS/2016/23966

A Straightforward and Receptive UV Spectrophotometric Method for the Determination of Ibandronate Sodium in Pharmaceutical Formulations and Bulk Drugs

Lubna Azmi, Ila Shukla, Shyam Sundar Gupta, Paramdeep Bagga & Ch. V. Rao · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aims: A uncomplicated and outlay efficient spectrophotometric method is developed for the determination of Ibandronate sodium in unadulterated form and in pharmaceutical formulations. Place and Duration of Study: Department of Pharmacognosy and Ethnopharmacology Division (Pilot p...

Open access Research Article 10.9734/JAMPS/2016/20079

Knowledge, Attitude and Practice about Household Poisoning in Saudi Arabia

Samia S. Barghash, Azza El. Tlt & Huda A. Al-Jemily · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Background: Food poisoning, household poisoning, and cosmetic poisoning are becoming a very important health problem both worldwide and locally at the level of the Kingdom of Saudi Arabia (KSA). The aims of this study was to assess knowledge, attitude and practice about the stora...

Open access Research Article 10.9734/JAMPS/2016/23115

Antibacterial Efficacy of Ageratum conyzoides on Salmonella Species Isolated from Suspected Typhoid Fever Patients in Akure Metropolis, Nigeria

O. E. Ajayi, S. I. Awala, F. N. Okogbue, A. G. Ogunleye & B. F. Olaleye · Journal of Advances in Medical and Pharmaceutical Sciences · 2016

Aim: The study aimed at assessing the antibacterial efficacy of Ageratum conyzoides on Salmonella species isolated from suspected typhoid fever patients in Akure metropolis, Nigeria. Study Design: The study evaluated the prospective use of Ageratum conyzoides as an alternative to...

Open access Research Article 10.9734/JAMPS/2016/23307