Gisella E. Alfonsino, Andrea Santagati, Livia Basile, Ettore Novellino, Corey Gaul, Carley Squires, Michael Braden, John M. Gerdes, Silvia Pérez Silanes, Salvatore Guccione & Keith K. Parker·Journal of Advances in Medical and Pharmaceutical Sciences·2015
Clinical depression encompasses a complex neurobiology involving multiple interacting systems. This intricate pathophysiology is, in part, correlated with dysfunction in serotonin (5HT) neurochemistry. The 5HT1a receptor (R) and SERT (serotonin transporter) components of this net...
Open access
Research Article10.9734/JAMPS/2015/18917
Aim: The association between insulin resistance and hirsutism in women is well studied. However there is no previous data about association between insulin resistance and male body hair density. Thus, the aim of the present study is to evaluate association between insulin resist...
Open access
Research Article10.9734/JAMPS/2015/19450
Background: Peripheral venous catheterization is a common medical procedure among hospitalized patients. Its use is fraught with potential complications including thrombophlebitis and blood stream infections. This necessitates provision of appropriate local protocols, meticulous...
Open access
Research Article10.9734/JAMPS/2015/19223
Aims: To identify isosteres and bioisosteres suitable for substitution on the molecular scaffold of meclofenamic acid and tolfenamic acid. The compounds will be studied to determine drug-likeness and other properties. Study Design: Isosteres and bioisosteres were selected and emp...
Open access
Research Article10.9734/JAMPS/2015/18954
Aim: Eruptive seborrhoeic keratoses are characterized by rapid onset of multiple seborrhoeic keratoses. They can be associated with internal malignancies, inflammatory dermatoses and drug reactions. Our aim was to present a case with eruptive seborrhoeic keratoses appeared during...
Open access
Research Article10.9734/JAMPS/2015/18850
Aim: The present study was carried out to investigate the possible toxic effects of the leaf aqueous extract from Eremomastax speciosa and also to evaluate the acceptable safety level of this extract in Wistar rats. Place and Duration of Study: Department of Animal Biology and Ph...
Open access
Research Article10.9734/JAMPS/2015/18361
In view of increased resistance of Plasmodium falciparum to almost all conventional antimalarial drugs, it has become necessary to search for new classes of molecules from traditional medicinal plants. Indeed, the best antimalarial drugs for which there are fewer cases of resista...
Open access
Research Article10.9734/JAMPS/2015/18138
Aims: To determine the prevalence of multidrug resistant (MDR) and Extended Spectrum β-lactamase producing (ESBL) E. coli in neonates, their mothers and healthcare workers (HCWs) in the neonatal wards of the University of Uyo Teaching Hospital (UUTH), Uyo-Nigeria. Study Design: I...
Open access
Research Article10.9734/JAMPS/2015/18742
Background: Pre-eclampsia is a common medical complication of pregnancy associated with increased maternal and perinatal mortality and morbidity. Its etiology is unknown, although several evidences indicate that deficiency of various nutritional elements might play important role...
Open access
Research Article10.9734/JAMPS/2015/18500
Chrysophyllum albidum (Sapotaceae), commonly called white star apple is a very useful medicinal plant common in the tropical and sub-tropical regions of the world. This review is an update assemblage on the traditional, phytochemical and ethno-pharmacological studies carried out...
Open access
Research Article10.9734/JAMPS/2015/18641
Although there are a considerable number of pain assessment scales, only some of them can be used for practical intentions. The Faces Pain Scale is used for children 4 to 6-7 years old, while the Visual Analog Scale (VAS) is used for children above this age. A study from December...
Open access
Research Article10.9734/JAMPS/2015/18533
Aims: The study was aimed at determining the lethal dose of the fruit of Tetrapleura tetraptera and ascertains the wound healing effect of its acetone fraction. Place and Duration of Study: The department of clinical pharmacy, faculty of pharmacy, University of Uyo, Nigeria, betw...
Open access
Research Article10.9734/JAMPS/2015/15776
The safety of Archachatina maginata haemolymph on biochemical and hematological indices of albino rats was investigated. Twelve white albino rats were grouped into 3 (A-C) of 4 animals each. Group A rats serve as control groups and received no treatment, while groups B and C rece...
Open access
Research Article10.9734/JAMPS/2015/16393
Aims: The hydromethanolic extract of D. dumetorum was evaluated for antinociceptive and antioxidant activities to validate its uses in traditional medicine for these purposes. Methods: The antioxidant activity of D. dumetorum was done in vitro using 2, 2-diphenyl-1-picrylhydrazyl...
Open access
Research Article10.9734/JAMPS/2015/18117
Plant-based medicinal products have been acknowledged since ancient times and several medicinal plants and their products have been used to control diabetes in the traditional medicinal systems of many cultures worldwide. Several synthetic oral hypoglycemic agents are the primary...
Open access
Research Article10.9734/JAMPS/2015/15873