Skip to content

All published articles 889

Extended Spectrum Beta-Lactamases in Clinical Isolates of Escherichia coli and Klebsiella pneumoniae from University of Uyo Teaching Hospital, Uyo-Nigeria

Innocent Azekhueme, Anietie E. Moses & Samuel D. Abbey · Journal of Advances in Medical and Pharmaceutical Sciences · 2015

Aims: This study was aimed to investigate the prevalence of ESBL-producing Escherichia coli and Klebsiella pneumoniae in clinical samples from University of Uyo Teaching Hospital (UUTH), Uyo-Nigeria, and determine their antimicrobial susceptibility profile. Study Design: This stu...

Open access Research Article 10.9734/JAMPS/2015/15384

Evaluation of Right Ventricular Diastolic Function in Patients with Chronic Obstructive Pulmonary Disease Using Pulsed Doppler Tissue Imaging

Aylin Ozsancak Ugurlu, Asli I Atar, Ilyas Atar, Oyku Gulmez, Serife Savas Bozbas, Haldun Muderrisoglu & Fusun Oner Eyuboglu · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Objective: To evaluate the global and segmental diastolic function of the right ventricle using pulsed tissue Doppler imaging (TDI) in patients with clinically stable chronic obstructive pulmonary disease (COPD) without pulmonary hypertension (PHT). Methods: Twenty stable patient...

Open access Research Article 10.9734/JAMPS/2015/14459

Antiretroviral Therapy Contribution to Patients Health in New Juaben Municipality

Frederick Owusu & Kwame Asare Gyasi-Agyei · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Our study focused on identifying factors underlining the deteriorating health condition of people living with HIV/AIDS (PLWHA) in the New Juaben Municipality. After a review of the relevant literature, the following hypotheses were developed: the attitude of PLWHA to antiretrovir...

Open access Research Article 10.9734/JAMPS/2015/13809

Isolation and Structural Characterization of the Most Active Antidiabetic Fraction of Corchorus olitorius Seed Extract

Maxwell Osaronowen Egua, E. U. Etuk, S. O. Bello & S. W. Hassan · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Aims: This study was carried out as a step  further  in our investigation of the antidiabetic properties of ethanolic seed extract of Corchorus olitorius (ewedu) in the bid to Isolate and Structurally Elucidate the Most Active Antidiabetic Fraction of Corchorus olitorius Seed Ext...

Open access Research Article 10.9734/JAMPS/2015/14855

Self-Medication with Antibiotics amongst Civil Servants in Uyo, Southern Nigeria

Eshiet Unyime Israel, Essien Grace Emmanuel, Effiong Grace Sylvester & Ekwueme Chukuma · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Background: Self-medication with antibiotics constitute a major form of irrational use of medicines and can cause significant adverse effects such as resistant microorganisms, treatment failure, drug toxicity, increase in treatment costs, prolong hospitalization period and increa...

Open access Research Article 10.9734/JAMPS/2015/15147

Diagnosis of Bilateral Type-A Radix Para-Molaris on Mandibular First Molars: A Case Report

Sathish Abraham, Neha Jaju, Priya Yawalikar & Rajan J. Mangrolia · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Successful endodontic treatment of a molar tooth having an additional root whether it is radix para/ento molaris; begins with proper diagnosis. Hence careful examination and assessment of intra oral peri-apical radiographs should be done prior to attempting access opening. These...

Open access Research Article 10.9734/JAMPS/2015/14756

Anti-inflammatory Activities of the Leaf Chloroform Extract of Palisota hirsuta

Madubuike G. Kelechi & Asuzu I. Uzoma · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Objective: To investigate the anti-inflammatory activity of the chloroform leaf extract of Palisota hirsuta (CLEPH). Methods: CLEPH was evaluated for anti-inflammatory activity using standard experimental models of inflammation namely: Croton oil-induced mouse ear edema, carragee...

Open access Research Article 10.9734/JAMPS/2015/13813

Age Related Serum Antimullerian Hormone Concentrations among Infertile Versus Fertile Women

Chelsi Goodman, María Bustillo, Arielle Port & Carolyn B. Coulam · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Aims: Antimullerian hormone (AMH) has been accepted as a marker for the size of the ovarian follicle pool. To interrupt the results of this investigation, age-specific concentrations are needed. The purpose of this study is to compare antimullerian hormone (AMH) concentrations am...

Open access Research Article 10.9734/JAMPS/2015/13883

Effect of Various Preservatives on Pectin Base of Ofloxacin Vaginal GEL

Ekaete Akpabio, Grace Essien, Timma Uwah & Clement Jackson · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

The effect of various preservatives such as Methyl paraben, Propyl paraben, benzoic acid and Methyl paraben, Propyl paraben (1:10) on a pectin – base ofloxacin vaginal gel was tested. Five batches of pectin-based ofloxacin vaginal gel were assessed by antibiotic sensitive test, d...

Open access Research Article 10.9734/JAMPS/2015/14211

The Effect of Silymarin on Serum Concentration of Soluble Apoptosis Markers in β-Thalassemia Major Patients Receiving Desferrioxamine

Nafiseh Esmaeil, Marjan Gharagozloo, Behjat Moayedi, Milad Mirmoghtadaei & Mahdi Ghatreh Samani · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Background: Despite appropriate chelation therapy with desferrioxamine, iron deposition in visceral organs causes tissue damage in thalassemia major patients. Excess iron can generate reactive oxygen species (ROS) that may lead to cell death and apoptosis. Therefore, antioxidants...

Open access Research Article 10.9734/JAMPS/2015/12818

Is Cystoid Macular Edema More Frequent In Vitrectomized Internal Limiting Membrane-Peeled Eyes Undergoing Phacoemulsification?

Heidi Laviers, Ian Dooley & Hadi Zambarakji · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Purpose/Aim of study: We postulate that the timing of phacoemulsification relative to pars plana vitrectomy, internal limiting membrane peel (before, during or after) and gas is an important risk factor for cystoid macular edema. Materials and Methods: We report a retrospective s...

Open access Research Article 10.9734/JAMPS/2015/12865

Analysis of O6-Methylguanine in Cancer Patient Blood during Administration of Cyclophosphamide Using Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry

Yahdiana Harahap, Rizka Andalusia, Yesa Crystalia, Shinta Ayu Nurfaradilla & Harmita . · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Aims: To determine O6-Methylguanine in Cancer Patient Blood during Administration of Cyclophosphamide using Ultra High Performance Liquid Chromatography-Tandem Mass Spectrometry. Place and Duration of Study: Dharmais Cancer Hospital and Bioavailability/Bioequivalence Laboratory,...

Open access Research Article 10.9734/JAMPS/2015/12953

Comparative Evaluation of the Quality Control Parameters and Hypoglycemic Drug Effect of Some Brands of Glibenclamide Tablet

S. O. Awofisayo, J. A. Nnamdi & A. J. Uwah · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Drug release profile and bioavailability indices have been well correlated with the quality of drug products. A comparative evaluation of the quality control parameters and hypoglycaemic drug performance check of some brands of glibenclamide tablets was studied. The physicochemic...

Open access Research Article 10.9734/JAMPS/2015/11206

Antioxidant and Hepatoprotective Activity of Methanolic Extract of Cassia sieberiana Leaves in Carbon Tetrachloride-induced Hepatotoxicity in Rats

Gideon K. Madubuike, Samuel O. Onoja & Maxwell I. Ezeja · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Aims: The study was aimed at evaluating the hepatoprotective and antioxidant activity of the methanolic extract of C. sieberiana leaves. Study Design: Hepatoprotective, in vitro and in vivo antioxidant activity. Place and Duration of Study: Department of Veterinary Physiology, Ph...

Open access Research Article 10.9734/JAMPS/2015/13443

Anti-sickling and Antibacterial Activities of Some Extracts from Gardenia ternifolia subsp. Jovis-tonantis (Welw.) Verdc. (Rubiaceae) and Uapaca heudelotii Baill. (Phyllanthaceae)

K. N. Ngbolua, D. S. T. Tshibangu, P. T. Mpiana, S. O. Mihigo, B. K. Mavakala, M. C. Ashande & L. C. Muanyishay · Journal of Advances in Medical and Pharmaceutical Sciences · 2014

Aims: To evaluate the antisickling and antibacterial activities of Gardenia ternifolia and Uapaca heudelotii. Study Design: Evaluation of the antisickling and antibacterial activities of anthocyanins and organic acids extracted from Gardenia ternifolia and Uapaca heudelotii In vi...

Open access Research Article 10.9734/JAMPS/2015/13427