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All published articles 889

Trimethylamine N-Oxide: A Dual-function Compound at the Intersection of Gut Microbiota Metabolism and Systemic Disease

Ali Danish Alvi, Ye Zhao, Zaid Iqbal, Muhammad Abubakar, Mirza Zeeshan Afzal & Arslan Habib · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Trimethylamine N-oxide (TMAO) is a dietary metabolite at the intersection of microbiota metabolism and host response. Chronically elevated TMAO has been associated with negative outcomes in cardiovascular, renal, and neurological disease and, at physiological levels, appears to s...

Open access Research Article 10.9734/jamps/2025/v27i11825

Ameliorative Effects of Ethanolic Extract of Vernonia amygdalina Leaves on Testicular Damage in Alloxan-Induced Diabetic Male Wistar Rats

Ezenwatu E. N. & Nweke O. E. · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aim: To evaluate the ameliorative effects of ethanolic extract of Vernonia amygdalina leaves on testicular damage in alloxan-induced diabetic male wistar rats. Methodology: Thirty adult male Wistar rats were randomly divided into six groups (A–F, n = 5). Group A served as control...

Open access Research Article 10.9734/jamps/2025/v27i11824

Balancing the Therapeutic and Adverse Effects of Oral Prednisone/Prednisolone: A Systematic Review

Samuel James Offor, Victory Edet Iyanam, Ekpeno Mbet Akpanowo & Uduak Ugonma Ndubuisi-Nnaji · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Prednisone and prednisolone are synthetic analogues of the natural steroid hormones produced by the adrenal cortex. They have anti-inflammatory, and immunosuppressant effects. Prednisone is biologically inert and in order to become active, it is converted to prednisolone in the l...

Open access Research Article 10.9734/jamps/2025/v27i10822

Computational Evaluation of Indole Alkaloids from Rauwolfia vomitoria as Potential Anticancer Agents: Molecular Docking and ADME Profiling

Nzube F. Ekpunobi, Sandra C. Okoye, Eddison I. Oghonyon, Chidimma R. Chukwunwejim, Merylann A. Ochieng, Oluwatosin T. Idowu, Sabbath Usen-Obong, Matthew O. Olushola & Agu, K.C · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Cancer continues to pose a major global health challenge, particularly in low- and middle-income countries, where treatment costs and accessibility remain limiting. Natural products such as Rauwolfia vomitoria have shown significant promise as alternative sources of b...

Open access Research Article 10.9734/jamps/2025/v27i10823

The Concept of Cell Generation to Patient-Specific Therapy: A Review of Induced Pluripotent Stem Cell Applications

Darren Toritseju Amiwero & Christian Esidogho Amiwero · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Induced pluripotent stem cells (iPSCs), are derived from the reprogramming of adult somatic cells and have become essential in biomedical research. Their pluripotency nature allows these cells to be converted into specific cell types for therapeutic applications. This article rev...

Open access Research Article 10.9734/jamps/2025/v27i10821

Comprehensive Physicochemical Characterization and GC-MS Profiling of Neelibhringadi Kera Tailam: A Traditional Ayurvedic Oil Formulation for Hair Growth

Maneesha KS, Reeshma CR, Anagha Mariya & Sibi Narayanan · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Introduction: Neelibhringadi Kera Tailam is a traditional Ayurvedic herbal oil formulated for promoting hair health, addressing issues such as hair loss, premature greying, scalp irritation, and infections. This study evaluates its composition, preparation, organoleptic, physicoc...

Open access Research Article 10.9734/jamps/2025/v27i10820

Ethnopharmacological Study of Plants Used against Malaria by Traditional Healers in the District of Dikodougou, North Côte d'Ivoire

Koffi Akissi Jeanne, Tano Konan Dominique, Kangah Orphée Michelle Alerte, RASMANE Kaddi Na Ahou, Akissi Zachée Louis Evariste & Yavo William · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Traditional medicine (TM) has been a cornerstone of healthcare in many cultures, particularly in Africa. TM has played an integral role in managing diseases such as malaria. In Côte d'Ivoire, limited access to medical facilities brought indigenous communities to use on herbal med...

Open access Research Article 10.9734/jamps/2025/v27i10819

Phytochemical Screening and Evaluation of the Antimicrobial Activity of Hydroethanolic Extract from the Leaves of Anogeissus leiocarpa (DC.) Guill. & Perr. (Combretaceae)

Sarr A, Dieng SIM, Mbaye AI, Dieng A, Dieng ML, Diatta K, Diatta W, Fadaïro MAD & Fall AD · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: For centuries, traditional medicine has been a source of reliable, acceptable and affordable healthcare for African populations. Despite the development of modern medicine in subsequent years, this tradition has spread widely from one country to another and from gener...

Open access Research Article 10.9734/jamps/2025/v27i10818

Retrospective Evaluation of Surgical Indications and Complication Etiologies

Nur -Un-Naher Nazme, Mst. Shorifa Rani & Tasnim Mahmud · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Urgent abdominal Re-exploration (UARs), the life-saving & obligatory operations, are performed for the treatment of number of complications that occurs after gynecological & obstetrical surgeries. Objective: The objective of the study was to evaluate the indic...

Open access Research Article 10.9734/jamps/2025/v27i9817

Ameliorative Effects of Mentha Piperita Methanolic Extract on Lead Acetate Incuced Femoral Alterations in Adult Male Wistar Rats

Doris Kosarachi Ogbuokiri, Ezeokafor Emmanuel Nonso, Felix Emeka Menkiti, Okeke Perpetua Onyinyechi, Ifemenam K. E., Egbunike C. G., Ifebi K. O., Ezeagu Darlington Kenechukwu & Nwozor Adaeze Divine · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Mentha piperita L. (Pepper mint) a medicinally important plant that is well-known and widely cultivated for its use in flavor, fragrance, medicinal and pharmaceutical application. The medicinal parts of pepper mint are the essential oil composed of menthol and menthone together w...

Open access Research Article 10.9734/jamps/2025/v27i9815

Preparation and Dietary Evaluation of Fortified Yoghurt with Snail Shells

Mou Ghosal & Avery Sengupta · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

The study aimed to develop fortified yoghurt made with snail shell powder, a natural and non-toxic compound rich in calcium carbonate (approximately 95% inorganic minerals) and other essential minerals, such as manganese, iron, copper, zinc, and sodium, to increase its nutritiona...

Open access Research Article 10.9734/jamps/2025/v27i9816

Validation of the Non-Mydriatic and Mydriatic Remidio (FOP) Camera with Artificial Intelligence in Screening Diabetic Retinopathy at Northern-Tanzania (2023-2024)

Ally Magero, William Makupa & Maria Kissanga · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Aims: This study aimed to evaluate the validity of non-mydriatic fundoscopy using a Remidio FOP Camera with Artificial intelligence to screen for Diabetic Retinopathy in Northern Tanzania, 2023-2024. Study Design: This study employed a community-based cross-sectional design. Plac...

Open access Research Article 10.9734/jamps/2025/v27i9814

Riboceine Mitigates Isoniazid-induced Hepatic Disturbances in Wistar Rats

Kennedy I. Amagon, Dorcas N. Gowon & Noel N. Wannang · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Isoniazid is an efficacious first line antitubercular drug, though elevations in liver enzymes have been reported. This study evaluated the role of riboceine in modulating isoniazid-induced organ injury in rats. Thirty-five Wistar albino rats of either sex were randomly divided i...

Open access Research Article 10.9734/jamps/2025/v27i9813

Body Mass Index (BMI) in Association with Diabetes, Hypertension, Comorbidity among Patients in the Buea Health District, Cameroon

Mondoa Sally Efeti, Nsagh Dickson Shey & Emmanuel Yenshu Vubo · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: The rising burden of hypertension and diabetes in sub-Saharan Africa has intensified the risk of chronic kidney disease (CKD), with body mass index (BMI) playing a critical role in metabolic health. However, limited evidence exists on the sociodemographic and clinical...

Open access Research Article 10.9734/jamps/2025/v27i9812

Tamarindus indica Leaf Extract as a Natural Analgesic, Anti-inflammatory, and CNS Depressant: Experimental Evidence in Mice

KHADIZA KHANAM, A. H. M. MOSTOFA KAMAL, MOSTAFIZUR RAHMAN, Shammi Akhter, SIMIN SHABNAM LOPA, MD. ATIKUL ISLAM, Md. Sarwar Jahan & NURUNNAHAR · Journal of Advances in Medical and Pharmaceutical Sciences · 2025

Background: Leaves of Tamarindus indica have long been used in traditional medicine for managing pain, inflammation, and nervous system disorders. This study aimed to scientifically assess these properties using experimental models in mice. Methods: The aqueous leaf extract of T....

Open access Research Article 10.9734/jamps/2025/v27i8811